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About 108 results

ALLMedicine™ Toxicology Center

Research & Reviews  40 results

Systems Modeling to Quantify Safety Risks in Early Drug Development: Using Bifurcation ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8137611
The AAPS Journal; Pin C, Collins T et. al.

May 22nd, 2021 - Quantitative Systems Toxicology (QST) models, recapitulating pharmacokinetics and mechanism of action together with the organic response at multiple levels of biological organization, can provide predictions on the magnitude of injury and recovery...

Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology...
https://doi.org/10.1124/jpet.120.000167
The Journal of Pharmacology and Experimental Therapeutics; Gyimesi M, Rauscher AÁ et. al.

Jan 21st, 2021 - Blebbistatin, para-nitroblebbistatin (NBleb), and para-aminoblebbistatin (AmBleb) are highly useful tool compounds as they selectively inhibit the ATPase activity of myosin-2 family proteins. Despite the medical importance of the myosin-2 family a...

The Toxicology Investigators Consortium Case Registry-the 2019 Annual Report.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7554287
Journal of Medical Toxicology : Official Journal of the A... Spyres MB, Farrugia LA et. al.

Oct 3rd, 2020 - The Toxicology Investigators Consortium (ToxIC) Registry was established by the American College of Medical Toxicology (ACMT) in 2010. The Registry collects data from participating sites with the agreement that all bedside medical toxicology consu...

Transitioning to Virtual: ACMT's 2020 Annual Scientific Meeting.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444446
Journal of Medical Toxicology : Official Journal of the A... Kopec KT, Stolbach A

Aug 26th, 2020 - The American College of Medical Toxicology (ACMT) 2020 Annual Scientific Meeting (ASM) was scheduled to be held in New York City, March 12-15, 2020, and had the largest conference registration in the history of ACMT's ASM. In the week prior to the...

Quantitative Systems Toxicology Modeling Predicts that Reduced Biliary Efflux Contribut...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7854848
Clinical Pharmacology and Therapeutics; Beaudoin JJ, Brock WJ et. al.

Aug 5th, 2020 - Patients with autosomal dominant polycystic kidney disease (ADPKD) exhibit enhanced susceptibility to tolvaptan hepatotoxicity relative to other patient populations. In a rodent model of ADPKD, the expression and function of the biliary efflux tra...

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Guidelines  1 results

ACMT Position Statement: Hospital Privileges for Physicians Practicing Medical Toxicology.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440314
Journal of Medical Toxicology : Official Journal of the A... American College Of Medical Toxicology

Aug 17th, 2016 - ACMT Position Statement: Hospital Privileges for Physicians Practicing Medical Toxicology.|2016|American College Of Medical Toxicology ,|standards,standards,standards,standards,standards,

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Drugs  2 results see all →