About 4,880 results

ALLMedicine™ Cleft Palate Center

Research & Reviews  1,831 results

Hearing, Speech, Language, and Communicative Participation in Patients With Apert Syndr...
The Journal of Craniofacial Surgery; Kilcoyne S, Luscombe C et. al.

Jul 27th, 2021 - Apert syndrome (AS) is caused by the heterozygous presence of 1 of 2 specific missense mutations of the fibroblast growth factor receptor 2 (FGFR2) gene. The 2 adjacent substitutions, designated p.Ser252Trp (S252W) and p.Pro253Arg (P253R), account...

Family based and case-control designs reveal an association of TFAP2A in nonsyndromic c...
Molecular Genetics & Genomic Medicine; Nguyen DM, Suzuki S et. al.

Jul 27th, 2021 - Dozens of causative genes and their mechanisms of nonsyndromic cleft lip with or without cleft palate (NSCL/P) were revealed through genome-wide association and linkage studies. Results were, however, not always replicated in different populations...

In-frame deletion of SPECC1L microtubule association domain results in gain-of-function...
Human Molecular Genetics; Goering JP, Wenger LW et. al.

Jul 25th, 2021 - Patients with autosomal dominant SPECC1L variants show syndromic malformations, including hypertelorism, cleft palate and omphalocele. These SPECC1L variants largely cluster in the second coiled-coil domain (CCD2), which facilitates association wi...

Maxillary Arch Dimensions in 6-Year-Old Cleft Children in Northern Finland: A Cross-Sec...
International Journal of Environmental Research and Publi... Corcoran M, Karki S et. al.

Jul 25th, 2021 - The aim was to cross-sectionally examine the maxillary arch dimensions in 6-year-old children with cleft lip and/or palate and to compare them with the initial cleft sizes among patients with cleft palate. The study included 89 patients with cleft...

Paper-thin roof: submucosal cleft palate with rhinolalia aperta.
Postgraduate Medical Journal; Tuang GJ, Zainal Abidin ZA

Jul 23rd, 2021 - Paper-thin roof: submucosal cleft palate with rhinolalia aperta.|2021|Tuang GJ,Zainal Abidin ZA,|

see more →

Guidelines  1 results

Clinical practice guidelines for the diagnosis and management of otitis media with effu...
Auris, Nasus, Larynx; Ito M, Takahashi H et. al.

May 6th, 2017 - To (1) indicate the definition, the disease state, methods of diagnosis, and testing for otitis media with effusion (OME) in childhood (<12 years); and (2) recommend methods of treatment in accordance with the evidence-based consensus reached by t...

see more →

Drugs  37 results see all →

Clinicaltrials.gov  27 results

Otologic and Rhinologic Outcomes in Children With Clef Palate

Mar 10th, 2020 - OBJECTIVE: To compare otologic and rhinologic outcomes in patients with cleft palate according to surgical protocols and type of cleft. DESIGN: Monocentric retrospective and prospective analysis of medical reports. PATIENTS, PARTICIPANTS: All cons...

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

Jan 13th, 2020 - 22q11.2 deletion syndrome is a disorder caused by the deletion of a small piece of chromosome 22. Most people with this disorder are missing a sequence of about 3 million DNA building blocks on chromosome 22 within each cell. This disorder affects...

Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)

Jul 23rd, 2019 - EPG has been used to treat apraxia of speech (AOS) as well as other speech production disorders (i.e., articulation disorders & cleft palate). SPT is one of the most systematically studied treatment approaches for AOS. Both treatment approaches ar...

Middle Ear Pressure Disregulation in Cleft Palate Patients

Feb 18th, 2019 - Otitis media with effusion (OME) is recognized as nearly universal in the population of infants and children with cleft palate (CP) and is often associated with long-standing conductive and, perhaps, sensorineural hearing losses. Most evidence sug...

Evaluation of Trigeminal Nerve Blockade

Oct 30th, 2018 - Cleft palate is a common congenital anomaly for which surgical repair is indicated during early childhood. The surgical repair of cleft palate is very painful, and generally requires high doses of opioids for adequate pain control, placing childre...

see more →

News  43 results

New Data on Birth Defects With Antidepressant Use in Pregnancy

Aug 18th, 2020 - Use of venlafaxine (Effexor), a serotonin-norepinephrine reuptake inhibitor (SNRI), is associated with more birth defects than any other antidepressant taken in the first months of pregnancy, new research suggests. Jennita Reefhuis, PhD "Our study...

New Data on Antiepileptic Drugs and Birth Defects

Sep 25th, 2019 - This transcript has been edited for clarity. Dear colleagues, I am Christoph Diener from the faculty of medicine at the University of Duisburg-Essen in Germany, here to discuss some highlights from the recent literature. I have five papers to shar...

Safety of ondansetron for nausea and vomiting of pregnancy

Aug 14th, 2019 - To date, although the data are conflicting, they are consistent with either a small increased risk for selected cardiac defects and perhaps cleft palate, or no increased risk at all. However, with recent data indicating that nearly one-quarter of.

Nonchromosomal Birth Defects Linked With Childhood Cancers

Apr 16th, 2018 - CHICAGO — In a retrospective analysis of registry data on more than 10 million live births, the risk for childhood cancers was 2.6-fold higher in children born with nonchromosomal abnormalities than in children born without any defects. In additio...

Risk of Oral Clefts with Topiramate May Be Dose-Dependent

Dec 30th, 2017 - Action Points The risk of oral clefts (cleft lip or palate) at birth was almost threefold higher among infants born to women exposed to topiramate compared with an unexposed group, with greater risk among women taking higher higher doses of the dr...

see more →

Patient Education  13 results see all →