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About 615 results

ALLMedicine™ Oral Leukoplakia Center

Research & Reviews  233 results

Oral leukoplakia; a clinicopathological study and malignant transformation.
https://doi.org/10.1111/odi.14123
Oral Diseases; Tovaru S, Costache M et. al.

Jan 5th, 2022 - To assess the clinicopathological characteristics of a cohort of patients with oral leukoplakia managed in a Romanian dental hospital and to evaluate the risk of malignant transformation. We conducted a hospital based retrospective study using the...

Biallelic TERT variant leads to Hoyeraal-Hreidarsson syndrome with additional dyskerato...
https://doi.org/10.1002/ajmg.a.62602
American Journal of Medical Genetics. Part A; Çepni E, Satkın NB et. al.

Dec 11th, 2021 - Short telomere syndromes constitute a heterogeneous group of clinical conditions characterized by short telomeres and impaired telomerase activity due to pathogenic variants in the essential telomerase components. Dyskeratosis congenita (DC) is a ...

Association Between X-Ray Repair Cross-Complementing Group 1 Arg399Gln Polymorphism and...
https://doi.org/10.1089/gtmb.2021.0105
Genetic Testing and Molecular Biomarkers; Wang J, Zhu C et. al.

Dec 11th, 2021 - Aims: Previous studies have have reported inconsistent results regarding the association of the XRCC1 polymorphism Arg399Gln with oral leukoplakia (OLK) risk. This study was designed to assess the existing evidence of this association using a meta...

A standalone approach to utilize telomere length measurement as a surveillance tool in ...
https://doi.org/10.1002/1878-0261.13133
Molecular Oncology; Pal J, Rajput Y et. al.

Nov 3rd, 2021 - Oral squamous cell carcinoma (OSCC) is often preceded by a white patch on a surface of the mouth, called oral leukoplakia (OL). As accelerated telomere length (TL) shortening in dividing epithelial cells may lead to oncogenic transformation, telom...

Associations between clinical and histopathological characteristics in oral leukoplakia.
https://doi.org/10.1111/odi.14038
Oral Diseases; Evren I, Brouns ER et. al.

Oct 4th, 2021 - To identify possible associations between patients' demographics and habits and the clinical aspects and histopathological characteristics of oral leukoplakia (OL) at patients' first visit. A total of 140 consecutive patients with OL at a single i...

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Clinicaltrials.gov  7 results

Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach
https://clinicaltrials.gov/ct2/show/NCT04858100

Apr 26th, 2021 - Different treatments have been proposed for the management of oral leukoplakia (OL) in order to prevent oral squamous cell carcinoma onset. However, there is still no consensus on the most effective approach for the patients affected by such oral ...

A Randomized Study of Sulindac in Oral Premalignant Lesions
https://clinicaltrials.gov/ct2/show/NCT00299195

Nov 19th, 2020 - Oral precancerous lesions (OPL) represent a valuable model for clinical trials for tobacco related cancers. However, due to the relatively low prevalence of this condition in the United States, subject accrual to such trials is slow. Conversely, i...

8-Hydroxy-2-Deoxyguanosine ,Total Antioxidant Capacity in Oral Premalignant and Malignant Lesions
https://clinicaltrials.gov/ct2/show/NCT03830710

Feb 20th, 2019 - Detection of molecular markers in saliva is superior to their detection in serum and other body fluids due to the fact of being an easy non-invasive tool requiring no training for its collection. Consequently, the aim of our work was to investigat...

Aspirin Mouthwash in Treating Patients With Oral Leukoplakia
https://clinicaltrials.gov/ct2/show/NCT01238185

Aug 12th, 2013 - OBJECTIVES: To determine if oral topical acetylsalicylic acid mouthwash achieves modulation of COX-1, COX-2, and prostaglandin in oral dysplasia tissues in patients with oral leukoplakia. To determine if this drug achieves alteration of histopatho...

Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia
https://clinicaltrials.gov/ct2/show/NCT00101335

Jul 11th, 2013 - OBJECTIVES: Primary Compare the clinical efficacy of celecoxib vs placebo, in terms of inducing regression of oral leukoplakia lesions, in patients with hyperplastic or dysplastic oral leukoplakia. Secondary Determine the effect of this drug in mo...

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News  6 results

Clinical Trials in Progress
https://www.onclive.com/view/clinical-trials-in-progress

Dec 5th, 2020 - The Trials in Progress section is intended to stimulate discussion about ongoing clinical trials and to promote collaboration across the oncology community. Each month, OBTN will present summaries of ongoing research in a broad range of cancer typ...

Tylosis in a Patient With Howel-Evans Syndrome: Management With Acitretin
https://www.mdedge.com/dermatology/article/231119/mixed-topics/tylosis-patient-howel-evans-syndrome-management-acitretin
Sabra M. Abner, MD, Audra Isaac, MD et. al.

Nov 4th, 2020 - To the Editor: Tylosis with esophageal cancer was first described by Howel-Evans et al1 in 1958 in a family from Liverpool, England. The disease is inherited in an autosomal-dominant fashion with a mutation in the tylosis with esophageal cancer ge.

Management Strategies for Oral Potentially Malignant Disorders
https://www.medscape.com/viewarticle/893975

Mar 16th, 2018 - Oral Potentially Malignant Disorders Oral potentially malignant disorders (OPMDs) include oral leukoplakia (OL), oral erythroplakia, oral submucous fibrosis, oral lichen planus, proliferative verrucous leukoplakia, and actinic keratosis. Once an O...

Who’s Responsible for Oral Lesions?
https://www.mdedge.com/clinicianreviews/article/77398/oncology/whos-responsible-oral-lesions
David M. Lang, JD, PA-C

Aug 30th, 2013 - Cases reprinted with permission from Medical Malpractice Verdicts, Settlements and Experts, Lewis Laska, Editor, (800) 298-6288. A 47-year-old man in Michigan went to his internist with complaints of oral discomfort and white patches on his tongue.

AACR: Less Cancer With NSAIDs But More Cardiovascular Deaths
https://www.medpagetoday.com/hematologyoncology/othercancers/902

Apr 18th, 2005 - Action Points This preliminary study suggests that NSAIDs reduce the risk of oral cancer. However, advise patients who inquire about these findings that this may place them at increased risk of death from heart disease. Advise smokers that smoking...

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