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About 753 results

ALLMedicine™ Oral Leukoplakia Center

Research & Reviews  275 results

Importance of the vaporization margin during CO2 laser treatment of oral leukoplakia, a...
https://doi.org/10.1111/odi.14345
Oral Diseases; Vilar-Villanueva M, Somoza-Martín JM et. al.

Aug 10th, 2022 - The main purpose of this study was to assess the response of oral leukoplakia to CO2 laser vaporization treatment, as well as determining possible factors that may affect recurrence of lesions. A retrospective study was conducted, in which the med...

Influence of PD-1/PD-L1 on immune micro-environment in oral leukoplakia and oral squamo...
https://doi.org/10.1111/odi.14332
Oral Diseases; Xu SB, Wang MY et. al.

Aug 4th, 2022 - To evaluate the relation between the expression of PD-1, PD-L1, CD3, CD8, Foxp3 and clinicopathological features as well as survival outcome in patients with oral leukoplakia (OLK) and oral squamous cell carcinomas (OSCC), and to study the effect ...

SNAI2 promotes the malignant transformation of oral leukoplakia by modulating p-EMT.
https://doi.org/10.1111/odi.14321
Oral Diseases; Shang Q, Peng J et. al.

Jul 28th, 2022 - Snail family transcriptional repressor 2 (SNAI2) is a key regulator of partial epithelial-mesenchymal transition (p-EMT), and is associated with tumorigenesis. Whether SNAI2 promotes oral leukoplakia (OLK) malignant transformation by modulating p-...

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
https://clinicaltrials.gov/ct2/show/NCT05237960

Jul 11th, 2022 - PRIMARY OBJECTIVE: I. To determine the histological response to extended release metformin hydrochloride (metformin) intervention in the target lesion. SECONDARY OBJECTIVES: I. Clinical response to metformin intervention in the target lesion. II. ...

Oral leukoplakia diagnosis and treatment in Europe and Australia: Oral Medicine Practit...
https://doi.org/10.1111/odi.14301
Oral Diseases; Pentenero M, Sutera S et. al.

Jul 7th, 2022 - The management of oral potentially malignant disorders (OPMD) including oral leukoplakia (OL) is not currently structured according to agreed guidelines. The current report presents survey data gathered from Oral Medicine Practitioners (OMPs) in E...

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Clinicaltrials.gov  21 results

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
https://clinicaltrials.gov/ct2/show/NCT05237960

Jul 11th, 2022 - PRIMARY OBJECTIVE: I. To determine the histological response to extended release metformin hydrochloride (metformin) intervention in the target lesion. SECONDARY OBJECTIVES: I. Clinical response to metformin intervention in the target lesion. II. ...

Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
https://clinicaltrials.gov/ct2/show/NCT01659606

Apr 29th, 2022 - Dyskeratosis congenita (DC) is an inherited multisystem disorder, which classically presents with a clinical triad of skin pigment abnormalities, nail dystrophy, and oral leukoplakia. DC is part of a spectrum of telomere biology disorders, which i...

Oral Cancer Screening for Early Detection of Premalignant Disorders (PMOD)
https://clinicaltrials.gov/ct2/show/NCT05296941

Mar 25th, 2022 - In Sweden, about 1,200 cases of cancer of the oral cavity, lips and throat are diagnosed each year. This is significantly higher than the global age-standardized incidence of 6.1 per 100,000 inhabitants, including all ages and genders. Oral cancer...

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia
https://clinicaltrials.gov/ct2/show/NCT00099021

Feb 11th, 2022 - PRIMARY OBJECTIVES: I. Determine whether pioglitazone (pioglitazone hydrochloride) reverses leukoplakia in patients with hyperplastic or dysplastic oral cavity or oropharyngeal leukoplakia. SECONDARY OBJECTIVES: I. Determine the safety and tolerab...

Oral Potentially Malignant Disorders: Comparison Between Surgical Treatment and Wait and See Approach
https://clinicaltrials.gov/ct2/show/NCT04858100

Apr 26th, 2021 - Different treatments have been proposed for the management of oral leukoplakia (OL) in order to prevent oral squamous cell carcinoma onset. However, there is still no consensus on the most effective approach for the patients affected by such oral ...

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News  5 results

Tylosis in a Patient With Howel-Evans Syndrome: Management With Acitretin
https://www.mdedge.com/dermatology/article/231119/mixed-topics/tylosis-patient-howel-evans-syndrome-management-acitretin
Sabra M. Abner, MD, Audra Isaac, MD et. al.

Nov 4th, 2020 - To the Editor: Tylosis with esophageal cancer was first described by Howel-Evans et al1 in 1958 in a family from Liverpool, England. The disease is inherited in an autosomal-dominant fashion with a mutation in the tylosis with esophageal cancer ge.

Management Strategies for Oral Potentially Malignant Disorders
https://www.medscape.com/viewarticle/893975

Mar 16th, 2018 - Oral Potentially Malignant Disorders Oral potentially malignant disorders (OPMDs) include oral leukoplakia (OL), oral erythroplakia, oral submucous fibrosis, oral lichen planus, proliferative verrucous leukoplakia, and actinic keratosis. Once an O...

Who’s Responsible for Oral Lesions?
https://www.mdedge.com/clinicianreviews/article/77398/oncology/whos-responsible-oral-lesions
David M. Lang, JD, PA-C

Aug 30th, 2013 - Cases reprinted with permission from Medical Malpractice Verdicts, Settlements and Experts, Lewis Laska, Editor, (800) 298-6288. A 47-year-old man in Michigan went to his internist with complaints of oral discomfort and white patches on his tongue.

AACR: Less Cancer With NSAIDs But More Cardiovascular Deaths
https://www.medpagetoday.com/hematologyoncology/othercancers/902

Apr 18th, 2005 - Action Points This preliminary study suggests that NSAIDs reduce the risk of oral cancer. However, advise patients who inquire about these findings that this may place them at increased risk of death from heart disease. Advise smokers that smoking...

Black hairy tongue
https://www.mdedge.com/ccjm/article/94866/dermatology/black-hairy-tongue
Sergio Vañó-Galván, MD, Pedro Jaén, PhD

A 71-year-old man presents for evaluation of an asymptomatic black discoloration of the tongue that he noticed several days earlier. The tongue does not itch or hurt, and the patient is otherwise well, although he is concerned about potential mali.

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