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About 5,450 results

ALLMedicine™ Angioedema Center

Research & Reviews  1,387 results

Addressing the individualized needs in hereditary angioedema: managed care strategies t...
https://doi.org/10.37765/ajmc.2022.88822
The American Journal of Managed Care; Malesker M

Jan 19th, 2022 - Hereditary angioedema (HAE) is a serious, potentially fatal disease of recurrent swelling of various subcutaneous and submucosal tissues throughout the body. Swelling is mediated by uncontrolled regulation of bradykinin, making it pathologically d...

Bizarre Cutaneous Ulcers due to Self-Administered Intravenous Dexketoprofen Trometamol.
https://doi.org/10.1177/15347346221074158
The International Journal of Lower Extremity Wounds; Akdogan N, Elcin G et. al.

Jan 18th, 2022 - Systemic non-steroidal anti-inflammatory drug use may result in various cutaneous complications including maculopapular rash, fixed drug eruption, urticaria, and angioedema most frequently. However extensive cutaneous ulcers in relation to intrave...

Updating the CoFAR Grading Scale for Systemic Allergic Reactions in Food Allergy.
https://doi.org/10.1016/j.jaci.2021.12.789
The Journal of Allergy and Clinical Immunology; Chinthrajah RS, Jones SM et. al.

Jan 14th, 2022 - Immunotherapy is promising as an efficacious treatment for food allergy. Other food allergy treatments are also under development. However, adverse allergic events (AE) during treatment, as well as during oral food challenges (OFC) are common and ...

Management of pregnancy in hereditary angioedema in a resource constrained setting: Our...
https://doi.org/10.1016/j.imbio.2022.152175
Immunobiology Jindal AK, Barman P et. al.

Jan 12th, 2022 - Hereditary angioedema (HAE) is a rare genetic disorder distinguished clinically by recurrent episodes of non-pruritic swelling. Although pregnancy has been considered a trigger, it may have variable effect on frequency of attacks of HAE. C1-inhibi...

The international WAO/EAACI guideline for the management of hereditary angioedema - the...
https://doi.org/10.1111/all.15214
Allergy Maurer M, Magerl M et. al.

Jan 11th, 2022 - Hereditary Angioedema (HAE) is a rare and disabling disease for which early diagnosis and effective therapy are critical. This revision and update of the global WAO/EAACI guideline on the diagnosis and management of HAE provides up-to-date guidanc...

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Guidelines  4 results

The international WAO/EAACI guideline for the management of hereditary angioedema-The 2...
https://doi.org/10.1111/all.13384
Allergy Maurer M, Magerl M et. al.

Jan 11th, 2018 - Hereditary Angioedema (HAE) is a rare and disabling disease. Early diagnosis and appropriate therapy are essential. This update and revision of the global guideline for HAE provides up-to-date consensus recommendations for the management of HAE. I...

A consensus parameter for the evaluation and management of angioedema in the emergency ...
https://doi.org/10.1111/acem.12341
Academic Emergency Medicine : Official Journal of the Soc... Moellman JJ, Bernstein JA et. al.

Apr 16th, 2014 - Despite its relatively common occurrence and life-threatening potential, the management of angioedema in the emergency department (ED) is lacking in terms of a structured approach. It is paramount to distinguish the different etiologies of angioed...

A focused parameter update: hereditary angioedema, acquired C1 inhibitor deficiency, an...
https://doi.org/10.1016/j.jaci.2013.03.034
The Journal of Allergy and Clinical Immunology; Zuraw BL, Bernstein JA et. al.

Jun 4th, 2013 - These parameters were developed by the Joint Task Force on Practice Parameters (JTFPP), representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the American College of Allergy, Asthma & Immunology (ACAAI); and the Joint Council ...

International consensus and practical guidelines on the gynecologic and obstetric manag...
https://doi.org/10.1016/j.jaci.2011.11.025
The Journal of Allergy and Clinical Immunology; Caballero T, Farkas H et. al.

Dec 27th, 2011 - There are a limited number of publications on the management of gynecologic/obstetric events in female patients with hereditary angioedema caused by C1 inhibitor deficiency (HAE-C1-INH). We sought to elaborate guidelines for optimizing the managem...

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Drugs  534 results see all →

Clinicaltrials.gov  50 results

Long-term Safety and Efficacy of CSL312 (Garadacimab) in the Prophylactic Treatment of Hereditary Angioedema Attacks
https://clinicaltrials.gov/ct2/show/NCT04739059

Jan 11th, 2022 - This phase 3b study will evaluate long-term safety and efficacy of CSL312 (also known as garadacimab) when administered subcutaneously (SC)

A Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II
https://clinicaltrials.gov/ct2/show/NCT04130191

Jan 4th, 2022 - The main aim of this study is to compare the number of HAE attacks occuring in persons using lanadelumab with the number of HAE attacks before lanadelumab treatment was started. Data from participants who start the study after 1 March 2021, will b...

STOP CSUA: phySical acTivity, mOod and sleeP in Chronic Spontaneous Urticaria and Angioedema
https://clinicaltrials.gov/ct2/show/NCT05169645

Dec 27th, 2021 - Chronic spontaneous urticaria and angioedema (CSUA) is a disease of the skin characterised by hives, swellings or both that last longer than 6 weeks (1). A quarter of patients with this disease report impaired quality of life (2). Furthermore, ind...

Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema
https://clinicaltrials.gov/ct2/show/NCT04618211

Dec 10th, 2021 - In Part I of the study, patients in non-attack state receive the assigned active single dose of PHA-022121 at the study center to assess pharmacokinetics (the way the body absorbs, distributes, and gets rid of the drug) and safety. In Part II of t...

Expanded Access for the Prevention of Acute Attacks of Hereditary Angioedema (HAE) in Pediatric Participants Aged 2 to Less Than (<) 12 Years
https://clinicaltrials.gov/ct2/show/NCT04583007

Oct 22nd, 2021 - This expanded access program enables the pediatric participants with a high unmet medical need to continue receiving lanadelumab during the interim period between completion of the SHP643-301 (NCT04070326 [SPRING study]) and Food and Drug Administ...

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News  198 results

COVID Shots Seem Safe for Hospital Staff With Allergy Risk
https://www.medscape.com/viewarticle/962290

Nov 4th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. An analysis of self-reported allergy risk and post-COVID-19 vaccination incidents — such as hives and angioedema — among the employees of a large ...

FDA Gives Thumbs Up to ANCA-Associated Vasculitis Drug
https://www.medpagetoday.com/rheumatology/generalrheumatology/94924

Oct 8th, 2021 - The FDA approved the oral complement 5a receptor inhibitor avacopan (Tavneos) for the treatment of severe, active antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, drugmaker ChemoCentryx announced on Friday. The drug will be recomm...

Momelotinib Trial Seeks to Address Myelofibrosis Symptoms
https://www.onclive.com/view/momelotinib-trial-seeks-to-address-myelofibrosis-symptoms

Oct 6th, 2021 - Momelotinib, an orally administered novel agent, is being evaluated in a phase 3 trial in patients with symptomatic and anemic myelofibrosis (MF), a population that experts say is in need of new options. The MOMENTUM trial (NCT04173494) will rando...

Expert Recommendations on the Diagnosis and Management of Long COVID
https://www.medscape.com/viewarticle/960243

Oct 5th, 2021 - It is estimated that one million people in the UK are currently living with long COVID, and with the total number of UK COVID-19 cases nearing 8 million, the further implications of long COVID for patients and healthcare services is uncertain. As ...

Quick Quiz Question 1
https://www.mdedge.com/gihepnews/article/246949/mixed-topics/quick-quiz-question-1

Oct 1st, 2021 - Correct answer: A. Rationale This patient has scromboid poisoning, which occurs when histidine is converted to histamine by bacterial enzymes in improperly refrigerated fish.

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Patient Education  7 results see all →