×
About 11,424 results
Atopic dermatitis/Eczema | DermNet NZ
https://www.dermnetnz.org/topics/atopic-dermatitis/

Jun 24th, 2019 - Atopic dermatitis is a chronic, itchy skin condition that is very common in children but may occur at any age. It is also known as eczema and atopic eczema and was formerly known as Besnier prurigo. It is the most common form of dermatitis. Atopic dermatitis usually occurs in people who have an 'atopic tendency'. This means they may develop any or all of three closely linked conditions; atop...

Eczema - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK538209/
Nemeth, V. et. al.

Jun 3rd, 2019 - Eczema, also known as atopic dermatitis, is the most common form of dermatitis. Genetic as well as environmental factors are thought to play a part in the pathogenesis. Eczema is most commonly seen in children but can be seen in adults. People with the disease tend to have dry, itchy skin that is prone to infection. Eczema is commonly known as the "itch that rashes" due to dry skin that lea...

The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing...
https://doi.org/10.1542/peds.2019-0281

Mar 17th, 2019 - This clinical report updates and replaces a 2008 clinical report from the American Academy of Pediatrics, which addressed the roles of maternal and early infant diet on the prevention of atopic disease, including atopic dermatitis, asthma, and food allergy. As with the previous report, the available data still limit the ability to draw firm conclusions about various aspects of atopy prevention ...

Children with atopic dermatitis may have unacknowledged contact allergies contributing ...
https://doi.org/10.1111/jdv.14737
Journal of the European Academy of Dermatology and Venereology : JEADV; Simonsen AB, Johansen JD et. al.

Dec 9th, 2017 - Whether children with atopic dermatitis have an altered risk of contact allergy than children without atopic dermatitis is frequently debated and studies have been conflicting. Theoretically, the impaired skin barrier in atopic dermatitis (AD) facilitates the penetration of potential allergens and several authors have highlighted the risk of underestimating and overlooking contact allergy in ch...

Melatonin Supplementation for Children With Atopic Dermatitis and Sleep Disturbance: A ...
https://doi.org/10.1001/jamapediatrics.2015.3092
JAMA Pediatrics; Chang YS, Lin MH et. al.

Nov 16th, 2015 - Sleep disturbance is common in children with atopic dermatitis (AD), but effective clinical management for this problem is lacking. Reduced levels of nocturnal melatonin were found to be associated with sleep disturbance and increased disease severity in children with AD. Melatonin also has sleep-inducing and anti-inflammatory properties and therefore might be useful for the management of AD. T...

Safety and efficacy of pimecrolimus in atopic dermatitis: a 5-year randomized trial.
https://doi.org/10.1542/peds.2014-1990
Pediatrics Sigurgeirsson B, Boznanski A et. al.

Mar 24th, 2015 - Atopic dermatitis (AD) primarily affects infants and young children. Although topical corticosteroids (TCSs) are often prescribed, noncorticosteroid treatments are needed because compliance with TCSs is poor due to concerns about their side effects. In this longest and largest intervention study ever conducted in infants with mild-to-moderate AD, pimecrolimus 1% cream (PIM) was compared with TC...

Vitamin D supplementation modulates the immune system and improves atopic dermatitis in...
https://doi.org/10.1159/000371350
International Archives of Allergy and Immunology; Di Filippo P, Scaparrotta A et. al.

Mar 20th, 2015 - Vitamin D seems to influence the evolution of atopic dermatitis (AD) in children. We tested the vitamin D serum levels of 39 children with AD (AD group t0) and of 20 nonallergic healthy controls (C group). AD severity was evaluated using the AD scoring system (SCORAD index). Cytokine serum levels (IL-2, IL-4, IL-6, IFN-γ, TNF-α) and atopy biomarkers were also measured. The patients were then tr...

Association Between Malignancy and Topical Use of Pimecrolimus.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465068
JAMA Dermatology; Margolis DJ, Abuabara K et. al.

Feb 18th, 2015 - A black box warning describes a potential risk of malignancy associated with topical use of pimecrolimus to treat atopic dermatitis due to its similarity to oral calcineurin inhibitors used in solid-organ transplantation and spontaneous reporting of malignancies, including lymphomas and cutaneous malignancies. To evaluate the risk of malignancy in a postmarketing study of children exposed to pi...

Atopic dermatitis: skin-directed management.
https://doi.org/10.1542/peds.2014-2812
Pediatrics Tollefson MM, Bruckner AL et. al.

Nov 25th, 2014 - Atopic dermatitis is a common inflammatory skin condition characterized by relapsing eczematous lesions in a typical distribution. It can be frustrating for pediatric patients, parents, and health care providers alike. The pediatrician will treat the majority of children with atopic dermatitis as many patients will not have access to a pediatric medical subspecialist, such as a pediatric dermat...

Randomized trial of vitamin D supplementation for winter-related atopic dermatitis in c...
https://doi.org/10.1016/j.jaci.2014.08.002
The Journal of Allergy and Clinical Immunology; Camargo CA, Ganmaa D et. al.

Oct 5th, 2014 - Epidemiologic and preclinical data, and a small randomized trial in Boston, suggest that vitamin D supplementation may improve winter-related atopic dermatitis (AD). To determine the effect of vitamin D supplementation on winter-related AD. We performed a randomized, double-blind, placebo-controlled trial of Mongolian children with winter-related AD (clinicaltrials.gov identifier: NCT00879424)....

Application of moisturizer to neonates prevents development of atopic dermatitis.
https://doi.org/10.1016/j.jaci.2014.07.060
The Journal of Allergy and Clinical Immunology; Horimukai K, Morita K et. al.

Oct 5th, 2014 - Recent studies have suggested that epidermal barrier dysfunction contributes to the development of atopic dermatitis (AD) and other allergic diseases. We performed a prospective, randomized controlled trial to investigate whether protecting the skin barrier with a moisturizer during the neonatal period prevents development of AD and allergic sensitization. An emulsion-type moisturizer was appli...

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180007
The Journal of Allergy and Clinical Immunology; Simpson EL, Chalmers JR et. al.

Oct 5th, 2014 - Atopic dermatitis (atopic eczema) is a chronic inflammatory skin disease that has reached epidemic proportions in children worldwide and is increasing in prevalence. Because of the significant socioeconomic effect of atopic dermatitis and its effect on the quality of life of children and families, there have been decades of research focused on disease prevention, with limited success. Recent ad...

Guidelines of care for the management of atopic dermatitis: section 3. Management and t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410179
Journal of the American Academy of Dermatology; Sidbury R, Davis DM et. al.

May 12th, 2014 - Atopic dermatitis is a chronic, pruritic inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important clinical questions that arise in atopic dermatitis management and care, providing recommendations based on the available evidence. In this third of 4 sections, treatment of atopic dermatitis with phototherapy and systemic immunomodulators...

The proactive wet-wrap method with diluted corticosteroids versus emollients in childre...
https://doi.org/10.1016/j.jaad.2014.01.898
Journal of the American Academy of Dermatology; Janmohamed SR, Oranje AP et. al.

Apr 4th, 2014 - Wet-wrap treatment (WWT) has been advocated as a relatively effective treatment in children with severe atopic dermatitis (AD). WWT often serves as crisis intervention for AD. We sought to evaluate the use of WWT with diluted corticosteroids in comparison with emollient in children with severe AD during 4 weeks in a proactive schedule during which the frequency of corticosteroid applications wa...

Increased food diversity in the first year of life is inversely associated with allergi...
https://doi.org/10.1016/j.jaci.2013.12.1044
The Journal of Allergy and Clinical Immunology; Roduit C, Frei R et. al.

Feb 10th, 2014 - The role of dietary factors in the development of allergies is a topic of debate, especially the potential associations between infant feeding practices and allergic diseases. Previously, we reported that increased food diversity introduced during the first year of life reduced the risk of atopic dermatitis. In this study we investigated the association between the introduction of food during t...

Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with na...
https://doi.org/10.1016/S0140-6736(19)31881-1
Lancet (London, England); Bachert C, Han JK et. al.

Sep 23rd, 2019 - Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) generally have a high symptom burden and poor health-related quality of life, often requiring recurring systemic corticosteroid use and repeated sinus surgery. Dupilumab is a fully human monoclonal antibody that inhibits signalling of interleukin (IL)-4 and IL-13, key drivers of type 2 inflammation, and has been approved for use in...

Infections in Dupilumab Clinical Trials in Atopic Dermatitis: A Comprehensive Pooled An...
https://doi.org/10.1007/s40257-019-00445-7
American Journal of Clinical Dermatology; Eichenfield LF, Bieber T et. al.

May 8th, 2019 - Patients with moderate-to-severe atopic dermatitis (AD) have increased infection risk, including skin infections and systemic infections. Immunomodulators (e.g., anti-tumor necrosis factors, anti-interleukin [anti-IL]-23, anti-IL-17, Janus kinase inhibitors) increase risk of infections. Dupilumab (a monoclonal antibody blocking the shared receptor component for IL-4 and IL-13) is approved for i...

Probiotic Supplementation for Prevention of Atopic Dermatitis in Infants and Children: ...
https://doi.org/10.1007/s40257-018-0404-3
American Journal of Clinical Dermatology; Li L, Han Z et. al.

Nov 22nd, 2018 - Probiotic supplementation in early life may be effective in preventing atopic dermatitis (AD); however, results regarding efficacy have been controversial. The aim of our study was to investigate the effect of probiotic supplementation on the risk of AD. We systematically searched PubMed, EBSCO, Embase and Web of Science databases up to 8 March 2018 for potentially relevant studies regarding pr...

Extent and consequences of inadequate disease control among adults with a history of mo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813133
The Journal of Dermatology; Wei W, Anderson P et. al.

Nov 13th, 2017 - Since control of atopic dermatitis (AD) remains challenging but has not been adequately characterized, the objective of this study was to characterize disease control among patients with a history of moderate to severe AD. Data were from the 2014 Adelphi US AD Disease Specific Programme, a cross-sectional survey of physicians (n = 202) and their patients with history of moderate to severe AD (n...

Effect of Oral Administration of a Mixture of Probiotic Strains on SCORAD Index and Use...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833582
JAMA Dermatology; Navarro-López V, Ramírez-Boscá A et. al.

Nov 8th, 2017 - Oral intake of new probiotic formulations may improve the course of atopic dermatitis (AD) in a young population. To determine whether a mixture of oral probiotics is safe and effective in the treatment of AD symptoms and to evaluate its influence on the use of topical steroids in a young population. A 12-week randomized, double-blind, placebo-controlled intervention trial, from March to June 2...