ALLMedicine™ Gangrene Center

May 19th, 2022 - To evaluate the efficacy of early necrotizing soft-tissue infections of the genitalia (NSTIG) component separation, primary wound closure (CSC). We hypothesized that early CSC would be safe, decrease the need for split-thickness skin grafting (STS...

May 16th, 2022 - The prevalence of peripheral artery disease (PAD) is estimated to be over 200 million. Critical limb ischemia (CLI) is considered the most advanced stage of PAD, occurring in about 10% of PAD patients. CLI patients typically present with ischemic ...

May 16th, 2022 - Dermatomyositis is a rare idiopathic inflammatory disease with diverse presentations that can have varying degrees of cutaneous and systemic involvement. This phenotypic heterogeneity makes DM a therapeutic challenge. Some therapeutic drugs, such ...

May 12th, 2022 - Raynaud phenomenon, with and without scleroderma, is a common vasospastic condition that manifests with extremity pain and skin discoloration. When conservative management fails, complications such as ischemia, ulceration, and gangrene may warrant...

May 10th, 2022 - Digital gangrene in a woman with scleroderma.|2022|Chatterjee S,|etiology,complications,

Jun 5th, 2019 - Chronic limb-threatening ischemia (CLTI) is associated with mortality, amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are focused on definition, evaluation, and management of CLTI with the goals of improving evide...

May 16th, 2022 - The prevalence of peripheral artery disease (PAD) is estimated to be over 200 million. Critical limb ischemia (CLI) is considered the most advanced stage of PAD, occurring in about 10% of PAD patients. CLI patients typically present with ischemic ...

Apr 22nd, 2022 - Study design: The entrance criteria specify adult diabetic patients (18-65 years) with chronic (>6 weeks) non-healing wounds(>2cm2) identified by study clinicians and counselled by aid of a Participant Information sheet (PIS). Having considered th...

Nov 15th, 2021 - Twenty-five CLI patients with ischemic forefoot rest pain, non-healing forefoot ulceration, or dry forefoot gangrene will be recruited. They will have already undergone standard of care evaluation, including hemodynamic testing and duplex ultrasou...

Oct 8th, 2021 - Diabetic foot ulcers (DFU) are one of the complications of diabetes mellitus resulting from multiple causes such as neuropathy, ischemia, and infection that contribute to morbidity and amputation. The prevalence of DFU has been estimated to be 3 t...

Sep 29th, 2021 - Impaired muscle strength has been reported in subjects with type 1 and type 2 diabetes as a late complication of severe diabetic peripheral neuropathy (DPN). However, reduction of muscle strength has been shown to occur earlier in the course of di...

Jan 5th, 2022 - Despite delays in screening and care during the COVID-19 pandemic, there wasn't a spike in diabetes-related foot amputations, a Canadian study found. In an analysis of nearly 1.5 million adults with diabetes living in Ontario, rates for nearly all...

Dec 8th, 2021 - (For more Reuters Special Reports, click on) RARITAN, New Jersey, Dec 8 (Reuters) - Gathered for an emergency meeting, the Johnson & Johnson drug safety team painted an alarming scene: People taking the company’s new blockbuster diabetes drug were...

Oct 5th, 2021 - Bone marrow derived autologous cell therapy (ACT) has been shown to significantly reduce the rate of major amputation at 5 years in people with diabetes who developed critical limb-threatening ischemia (CLTI). In a study of 130 patients, 64% of 42...

Jun 10th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. As the highly transmissible Delta coronavirus variant continues to devastate India and spread to other nations, health experts are reiterating the...

Apr 30th, 2021 - FDA expanded the indication for dapagliflozin (Farxiga) into chronic kidney disease (CKD). The drug, which first entered the market for type 2 diabetes in 2014, was approved to reduce the risk of kidney function decline, kidney failure, cardiovasc...