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About 1,053 results

ALLMedicine™ Yaws Center

Research & Reviews  161 results

A combined effort of 11 laboratories in the WHO African region to improve quality of Bu...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668193
PLoS Neglected Tropical Diseases; Marion E, Hycenth N et. al.

Nov 5th, 2022 - Buruli ulcer is one of the 20 neglected tropical diseases in the world. This necrotizing hypodermitis is a chronic debilitating disease caused by an environmental Mycobacterium ulcerans. At least 33 countries with tropical, subtropical and tempera...

Mathematical modelling Treponema infection in free-ranging Olive baboons (Papio anubis)...
https://doi.org/10.1016/j.epidem.2022.100638
Epidemics Hawkins D, Kusi R et. al.

Oct 26th, 2022 - Yaws is a chronic infection caused by the bacterium Treponema pallidum susp. pertenue (TPE) that was thought to be an exclusive human pathogen but was recently found and confirmed in nonhuman primates. In this paper, we develop the first compartme...

Skin wounds in a rural setting of Côte d'Ivoire: Population-based assessment of the bur...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9560139
PLoS Neglected Tropical Diseases; Toppino S, N'Krumah RTAS et. al.

Oct 14th, 2022 - Data on the burden and clinical epidemiology of skin wounds in rural sub-Saharan Africa is scant. The scale of the problem including preventable progression to chronic wounds, disability and systemic complications is largely unaddressed. We conduc...

Improved rapid diagnostic tests to detect syphilis and yaws: a systematic review and me...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9685714
Sexually Transmitted Infections; Zhang Y, Goh SM et. al.

Oct 1st, 2022 - Current rapid tests for syphilis and yaws can detect treponemal and non-treponemal antibodies. We aimed to critically appraise the literature for rapid diagnostic tests (RDTs) which can better distinguish an active infection of syphilis or yaws. W...

Digital Toolkit for Skin Diseases in LMICs
https://clinicaltrials.gov/ct2/show/NCT05300399

Sep 27th, 2022 - Background: The prevalence of skin diseases is extremely high in sub-Saharan Africa, among which are skin neglected tropical diseases (skin NTDs) that could lead to life-long disabilities and deformities if not diagnosed and treated early. To achi...

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Drugs  243 results see all →

Clinicaltrials.gov  10 results

Digital Toolkit for Skin Diseases in LMICs
https://clinicaltrials.gov/ct2/show/NCT05300399

Sep 27th, 2022 - Background: The prevalence of skin diseases is extremely high in sub-Saharan Africa, among which are skin neglected tropical diseases (skin NTDs) that could lead to life-long disabilities and deformities if not diagnosed and treated early. To achi...

Evaluation of a LAMP Assay for T. Pallidum. Pertenue
https://clinicaltrials.gov/ct2/show/NCT04753788

Apr 12th, 2022 - This is a diagnostic evaluation comparing the performance of real-time PCR performed at a national reference laboratory and a LAMP assay performed at a regional hospital for the diagnosis of yaws

Evaluation of an Intensive 3-round MDA Strategy Towards Yaws Eradication
https://clinicaltrials.gov/ct2/show/NCT03490123

Jun 23rd, 2021 - In 2013 WHO piloted the yaws eradication MDA strategy in several countries, including PNG. A study carried out on Lihir Island has shown that 1-round MDA with single-dose oral AZI reduced the prevalence of yaws by 90% at 12-months. However, this d...

Azithromycin - Ivermectin Mass Drug Administration for Skin Disease
https://clinicaltrials.gov/ct2/show/NCT02775617

Sep 17th, 2019 - This is an open-label prospective community intervention trial to assess the impact of community mass treatment with azithromycin for yaws and ivermectin for scabies, on non-yaws bacterial skin infections. Communities will be randomised to receive...

Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )
https://clinicaltrials.gov/ct2/show/NCT03676140

Feb 28th, 2019 - Recent studies have shown that single-dose combination therapy with three antifilarial drugs (Ivermectin [IVE] + DEC + ALB) called IDA is superior to current regimens used in LF elimination and may help accelerate LF elimination. WHO guidelines ha...

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News  7 results

Three Rounds of Antibiotic Therapy Superior to Targeted Treatment for Reducing Yaws Cases
https://www.medscape.com/viewarticle/966116

Jan 6th, 2022 - (Reuters Health) - As a strategy for halting the spread of yaws, mass administration of three rounds of azithromycin at six-month intervals was four times more effective than a single round followed by two rounds of targeted treatment, according t...

What Neglected Tropical Diseases Teach Us About Stigma
https://www.mdedge.com/dermatology/article/209336/infectious-diseases/what-neglected-tropical-diseases-teach-us-about?channel=234
Aileen Y. Chang, MD, Maria T. Ochoa, MD

Oct 3rd, 2019 - Neglected tropical diseases (NTDs) are a group of 20 diseases that typically are chronic and cause long-term disability, which negatively impacts work productivity, child survival, and school performance and attendance with adverse effect on futur.

What Neglected Tropical Diseases Teach Us About Stigma
https://www.mdedge.com/dermatology/article/209336/infectious-diseases/what-neglected-tropical-diseases-teach-us-about
Aileen Y. Chang, MD, Maria T. Ochoa, MD

Oct 3rd, 2019 - Neglected tropical diseases (NTDs) are a group of 20 diseases that typically are chronic and cause long-term disability, which negatively impacts work productivity, child survival, and school performance and attendance with adverse effect on futur.

ID Break: Clean Hands, Fewer Abx; $11 Million HIV Cure?; MenB Vax for Kids
https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/71157

Feb 14th, 2018 - It's official: influenza-associated hospitalizations are significantly higher this flu season than when the CDC started its current tracking system in 2010. The portion of pneumonia and influenza-associated deaths has passed the 10% threshold. Che...

Single Dose of Azithromycin Effective for Latent Yaws
https://www.medscape.com/viewarticle/888290

Nov 11th, 2017 - NEW YORK (Reuters Health) – A single dose of azithromycin, known to cure active yaws, also effectively treat latent yaws, researchers say. Dr. Oriol Mitja of the University of Barcelona, Spain, told Reuters Health, "Yaws is a neglected tropical sk...

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