ALLMedicine™ Cylindroma Center

Nov 12th, 2020 - Brooke-Spiegler Syndrome (BSS) is a very rare autosomal dominant hereditary disease which arises from heterozygous mutations in the CYLD gene. Patients with BSS are predisposed to multiple skin appendage tumors such as cylindromas, which are benig...

Oct 14th, 2020 - Spiradenocarcinoma (SC) is a very rare malignant skin adnexal tumor with sweat gland differentiation that develops from a pre-existing spiradenoma, cylindroma, or hybrid tumor called spiradenocylindroma, or arises de novo. We present two exception...

Sep 6th, 2020 - Mutations in the tumor suppressor CYLD, known to be causative of cylindromas, were recently described in a subset of high-risk (hr) HPV-positive head and neck squamous cell carcinomas (HNSCC). Pathologic and genetic characterization of these CYLD-...

Jul 12th, 2020 - Cylindroma, an uncommon presentation on 18F-DCFPyL PET/CT.|2020|Koene BPF,Bodar YJL,Meijer D,Jaspars EH,Vis AN,|

May 28th, 2020 - Rare reports of anal carcinoma (AC) describe histologic resemblance to cutaneous cylindroma, but mutations in the tumor suppressor CYLD, the gene responsible for familial and sporadic cylindromas, have not been systematically investigated in AC. H...

Nov 12th, 2020 - Brooke-Spiegler Syndrome (BSS) is a very rare autosomal dominant hereditary disease which arises from heterozygous mutations in the CYLD gene. Patients with BSS are predisposed to multiple skin appendage tumors such as cylindromas, which are benig...

Oct 14th, 2020 - Spiradenocarcinoma (SC) is a very rare malignant skin adnexal tumor with sweat gland differentiation that develops from a pre-existing spiradenoma, cylindroma, or hybrid tumor called spiradenocylindroma, or arises de novo. We present two exception...

Sep 6th, 2020 - Mutations in the tumor suppressor CYLD, known to be causative of cylindromas, were recently described in a subset of high-risk (hr) HPV-positive head and neck squamous cell carcinomas (HNSCC). Pathologic and genetic characterization of these CYLD-...

Jul 12th, 2020 - Cylindroma, an uncommon presentation on 18F-DCFPyL PET/CT.|2020|Koene BPF,Bodar YJL,Meijer D,Jaspars EH,Vis AN,|

May 28th, 2020 - Rare reports of anal carcinoma (AC) describe histologic resemblance to cutaneous cylindroma, but mutations in the tumor suppressor CYLD, the gene responsible for familial and sporadic cylindromas, have not been systematically investigated in AC. H...

Apr 8th, 2015 - Cylindromas are composed of basaloid islands interconnected in a jigsaw puzzle configuration (Figure 5B). 4 Similar to spiradenomas, they also are composed of 2 cell populations.

Jan 19th, 2015 - The Diagnosis: Dermal Cylindroma Microsopic evaluation of a tangential biopsy revealed findings of a dermal process consisting of well-circumscribed islands of pale and darker blue cells with little cytoplasm outlined by a hyaline basement membran.

Jan 11th, 2011 - ORLANDO - Surgical excision is the preferred approach for treating a patient who presents with a cylindroma or with the more extensive familial cylindromatosis, Dr. Leonard Slazinski said.