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About 393 results

ALLMedicine™ Spitz Nevus Center

Research & Reviews  191 results

Spitz nevus with a novel TFG-NTRK2 fusion: The first case report of NTRK2-rearranged Sp...
https://doi.org/10.1111/cup.14062
Journal of Cutaneous Pathology; Goto K, Pissaloux D et. al.

May 12th, 2021 - Fusions of ALK, ROS1, NTRK1, NTRK3, RET, MET, MERTK, FGFR1, ERBB4, LCK, BRAF, MAP3K8, MAP3K3, and PRKDC and mutation of HRAS have so far been discovered as the genetic alterations associated with the pathogenesis of Spitz neoplasms. This report pr...

Giant lung metastasis of NRAS-mutant melanoma in a 24-year-old patient with a history o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586673
Diagnostic Pathology; Vachtenheim J, Kodet R et. al.

Oct 26th, 2020 - Spitzoid melanocytic lesions represent a heterogeneous group of proliferations with ambiguous and overlapping terminology. The exact distinction of a Spitz nevus from a Spitzoid melanoma can be very difficult or, in some cases, impossible. Among t...

ALK-positive compound Spitz nevus with extensive perineural and intraneural neurotropism.
https://doi.org/10.1111/cup.13890
Journal of Cutaneous Pathology REFERENCES; Brown RA, Wang JY et. al.

Oct 9th, 2020 - Historically recognized by their characteristic histopathologic features, Spitz neoplasms are now known to be molecularly defined by mutually exclusive recurrent abnormalities that cause activation of the MAPK pathway. Spitz neoplasms with ALK rea...

Clinical and histopathological features of pagetoid Spitz nevi of the thigh.
https://doi.org/10.1111/cup.13854
Journal of Cutaneous Pathology REFERENCES; Chung J, Yuan ZM et. al.

Aug 23rd, 2020 - Pagetoid Spitz nevus is a rare subtype of Spitz nevus usually found on the lower extremities, particularly on the thigh of women. As a rare and under-recognized entity that can be misdiagnosed as melanoma, further characterization of clinical and ...

Verrucous Spitz Nevus.
https://doi.org/10.1016/j.jpeds.2020.07.035
The Journal of Pediatrics; Valdivielso-Ramos M, Roldan D et. al.

Jul 14th, 2020 - Verrucous Spitz Nevus.|2020|Valdivielso-Ramos M,Roldan D,Alonso S,|

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Clinicaltrials.gov  193 results

Spitz nevus with a novel TFG-NTRK2 fusion: The first case report of NTRK2-rearranged Sp...
https://doi.org/10.1111/cup.14062
Journal of Cutaneous Pathology; Goto K, Pissaloux D et. al.

May 12th, 2021 - Fusions of ALK, ROS1, NTRK1, NTRK3, RET, MET, MERTK, FGFR1, ERBB4, LCK, BRAF, MAP3K8, MAP3K3, and PRKDC and mutation of HRAS have so far been discovered as the genetic alterations associated with the pathogenesis of Spitz neoplasms. This report pr...

Expert Offers Tips for Sorting Out Pink Lesions on Dermoscopy
https://www.medscape.com/viewarticle/945115

Feb 1st, 2021 - Even in the most experienced hands, dermoscopy poses a challenge when the usual pigment clues are lacking to help distinguish melanoma from amelanotic melanoma and pigmented basal cell carcinoma (BCC) from nonpigmented BCC. Dr Jennifer Stein "For ...

Giant lung metastasis of NRAS-mutant melanoma in a 24-year-old patient with a history o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7586673
Diagnostic Pathology; Vachtenheim J, Kodet R et. al.

Oct 26th, 2020 - Spitzoid melanocytic lesions represent a heterogeneous group of proliferations with ambiguous and overlapping terminology. The exact distinction of a Spitz nevus from a Spitzoid melanoma can be very difficult or, in some cases, impossible. Among t...

ALK-positive compound Spitz nevus with extensive perineural and intraneural neurotropism.
https://doi.org/10.1111/cup.13890
Journal of Cutaneous Pathology REFERENCES; Brown RA, Wang JY et. al.

Oct 9th, 2020 - Historically recognized by their characteristic histopathologic features, Spitz neoplasms are now known to be molecularly defined by mutually exclusive recurrent abnormalities that cause activation of the MAPK pathway. Spitz neoplasms with ALK rea...

Clinical and histopathological features of pagetoid Spitz nevi of the thigh.
https://doi.org/10.1111/cup.13854
Journal of Cutaneous Pathology REFERENCES; Chung J, Yuan ZM et. al.

Aug 23rd, 2020 - Pagetoid Spitz nevus is a rare subtype of Spitz nevus usually found on the lower extremities, particularly on the thigh of women. As a rare and under-recognized entity that can be misdiagnosed as melanoma, further characterization of clinical and ...

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News  9 results

Expert Offers Tips for Sorting Out Pink Lesions on Dermoscopy
https://www.medscape.com/viewarticle/945115

Feb 1st, 2021 - Even in the most experienced hands, dermoscopy poses a challenge when the usual pigment clues are lacking to help distinguish melanoma from amelanotic melanoma and pigmented basal cell carcinoma (BCC) from nonpigmented BCC. Dr Jennifer Stein "For ...

Wart's That Lesion?
https://www.mdedge.com/clinicianreviews/article/118656/dermatology/warts-lesion/page/0/1

Dec 1st, 2016 - DISCUSSION The pathology report showed both epithelioid and spindle cells with scattered apoptotic cells seen at the dermoepidermal junction, with no atypia. The margins were clear.

Spitz Nevi Difficult to Categorize, Manage
https://www.mdedge.com/dermatology/article/10020/melanoma/spitz-nevi-difficult-categorize-manage
Sherry Boschert

SAN FRANCISCO — Follow-up on 219 patients with Spitz nevi found that 7 (3%) developed malignant melanoma, and in each case the original biopsy showed an atypical or desmoplastic Spitz nevus. The patients who developed melanoma also were older (age.

Spitz Nevus and Atypical Spitzoid Neoplasm
https://www.mdedge.com/dermatology/article/57311/melanoma/spitz-nevus-and-atypical-spitzoid-neoplasm

Maria Miteva, MD, and Rossitza Lazova, MD Spitz nevus (SN) and Spitzoid malignant melanoma (SMM) represent benign and malignant counterparts at both ends of the spectrum of Spitzoid lesions. Atypical Spitzoid neoplasm (ASN) is a poorly defined and.

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