About 213 results

ALLMedicine™ Dysplastic Nevus Center

Research & Reviews  61 results

Combined utility of p16 and BRAF V600E in the evaluation of spitzoid tumors: Superiorit...
Journal of Cutaneous Pathology; McAfee JL, Scarborough R et. al.

Oct 20th, 2022 - Spitzoid melanocytic neoplasms are diagnostically challenging; criteria for malignancy continue to evolve. The ability to predict chromosomal abnormalities with immunohistochemistry (IHC) could help select cases requiring chromosomal evaluation. F...

Dysplastic Nevus Part II: Dysplastic Nevi: Molecular/Genetic Profiles and Management.
Journal of the American Academy of Dermatology; Spaccarelli N, Drozdowski R et. al.

Oct 18th, 2022 - Dermatologists frequently see patients with clinically atypical nevi (CAN) and dermatopathologists interpret histologically dysplastic nevi (HDN) on a near-daily basis, but there is great variability in the definition and management of such lesion...

Differences in Nomenclature Usage and Preference Among Dermatopathologists for "Dysplas...
Journal of Cutaneous Pathology; Green AR, Moshiri A et. al.

Oct 15th, 2022 - Ongoing controversy exists regarding terminology used to describe atypical melanocytic nevi. Efforts to standardize nomenclature, including the 1992 NIH consensus conference, have been largely unsuccessful. Significant advances have revealed an in...

Dysplastic Nevus Part I:Historical Perspective, Classification, and Epidemiology.
Journal of the American Academy of Dermatology; Drozdowski R, Spaccarelli N et. al.

Aug 30th, 2022 - Since the late 1970's, the diagnosis and management of dysplastic nevi have been areas fraught with controversy in the fields of dermatology and dermatopathology. Diagnostic uncertainty and lack of standardized nomenclature continue to propagate c...

Dysplastic melanocytic nevus: Are molecular findings the key to the diagnosis?
Annals of Diagnostic Pathology; Xavier-Junior JCC, Ocanha-Xavier JP

Jul 16th, 2022 - The primary differential diagnosis of melanoma is dysplastic nevus. Until now, the final diagnosis is based on histological findings. With modern techniques, pathologists receive very early melanocytic lesions, which do not fit all malignant crite...

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Clinicaltrials.gov  2 results

A Prospective Natural History Study in Uveal Melanoma

Jun 30th, 2022 - Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, accounting for 85% to 95% of ocular melanoma cases. However, UM represents only about 3% to 5% of all melanomas in the United States (US). UM most commonly arises fro...

Tretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus Syndrome

Jan 2nd, 2019 - OBJECTIVES: I. Compare the efficacy (clinical and histologic evidence of regression) of topical tretinoin with or without systemic fenretinide in patients with dysplastic nevi with personal or family history of cutaneous melanoma. OUTLINE: This is...

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News  22 results

Melanoma: An FP’s guide to diagnosis and management
MDedge Family Medicine; Wendi Wohltmann, MD, FAAD, Jessica Servey, MD, MHPE, FAAFP

Jul 20th, 2021 - CASE A 48-year-old man comes to your clinic with a dark nevus on his right upper arm that appeared 2 months earlier. He says that the lesion has continued to grow and has bled (he thought because he initially picked at it).

Imaging a Helpful Sidekick in Detecting Melanomas

Mar 17th, 2021 - Regular skin surveillance using total body imaging was helpful for picking up malignant melanomas in high-risk people, researchers reported. In an Australian study of 593 adults, a structured surveillance program involving total-body photography (...

Dysplastic Nevi: Monitoring and Management

Oct 25th, 2018 - Dysplastic Nevi Since their original characterization by Clark and colleagues in 1978,[1] dysplastic nevi have posed a management dilemma, given their position in the gray area between benign melanocytic nevi and malignant melanoma. Even their his...

Dysplastic Nevi: Monitoring and Management

Oct 25th, 2018 - Dysplastic Nevi Since their original characterization by Clark and colleagues in 1978,[1] dysplastic nevi have posed a management dilemma, given their position in the gray area between benign melanocytic nevi and malignant melanoma. Even their his...

Re-excision unnecessary in moderately dysplastic nevi with positive margins
M. Alexander Otto

Sep 27th, 2018 - ORLANDO – Re-excisions are not needed when clinically excised moderately dysplastic nevi have positive histologic margins, based on results of a retrospective study of 438 patients who were treated at nine academic medical centers in the United St.

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