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About 183 results

ALLMedicine™ Spitz Nevus Center

Research & Reviews  62 results

Immunophenotype of tumor-infiltrating lymphocytes in atypical Spitzoid tumors according...
https://doi.org/10.1016/j.anndiagpath.2022.151985
Annals of Diagnostic Pathology; Moysset I, Fuster-Anglada C et. al.

Jun 17th, 2022 - The aims of the study were to investigate and compare the immunophenotype of tumor-infiltrating lymphocytes (TILs) and PD-L1 expression in a series of benign, intermediate and malignant Spitzoid lesions showing marked inflammatory lymphoid compone...

PRAME immunohistochemistry of spitzoid neoplasms.
https://doi.org/10.1111/cup.14245
Journal of Cutaneous Pathology; Koh SS, Lau SK et. al.

May 1st, 2022 - Spitzoid melanocytic neoplasms are well known to be diagnostically challenging. Immunohistochemistry (IHC) and molecular approaches have been used as ancillary diagnostic tests. Herein, we investigate the use of PRAME IHC for the assessment of spi...

"Concomitant" Cutaneous and Nodal Spitz Nevus/Tumor: A New Scenario for an Old Problem.
https://doi.org/10.1097/DAD.0000000000002148
The American Journal of Dermatopathology; Ferrara G, Lattanzi V et. al.

Feb 17th, 2022 - Spitz tumors are notoriously characterized by a high propensity to nodal involvement with a morphologically malignant (intraparenchymal) pattern but with little or no tendency toward further spread. We describe a case of spindle cell Spitz neoplas...

Light Brown and Pink Macule on the Upper Arm
https://www.mdedge.com/dermatology/article/251526/dermatopathology/light-brown-and-pink-macule-upper-arm
Richard Bindernagel, DO, Lisa Fronek, DO et. al.

Feb 7th, 2022 - The Diagnosis: Desmoplastic Spitz Nevus Desmoplastic Spitz nevus is a rare variant of Spitz nevus that commonly presents as a red to brown papule on the head, neck, or extremities. It is pertinent to review the histologic features of this neoplasm.

Spitz nevus with EHBP1-ALK fusion and distinctive membranous localization of ALK.
https://doi.org/10.1111/cup.14209
Journal of Cutaneous Pathology; Bahrani E, Kunder CA et. al.

Feb 4th, 2022 - ALK rearrangements define a histopathologically distinctive yet diverse subset of Spitz tumors characterized by fusiform to epithelioid melanocytes with frequent fascicular growth and ALK overexpression. Molecularly, these tumors are characterized...

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News  11 results

Light Brown and Pink Macule on the Upper Arm
https://www.mdedge.com/dermatology/article/251526/dermatopathology/light-brown-and-pink-macule-upper-arm
Richard Bindernagel, DO, Lisa Fronek, DO et. al.

Feb 7th, 2022 - The Diagnosis: Desmoplastic Spitz Nevus Desmoplastic Spitz nevus is a rare variant of Spitz nevus that commonly presents as a red to brown papule on the head, neck, or extremities. It is pertinent to review the histologic features of this neoplasm.

A female toddler presents with an itchy yellow nodule
https://www.mdedge.com/pediatrics/article/246672/dermatology/female-toddler-presents-itchy-yellow-nodule
MDedge Pediatrics; Lawrence Eichenfield, MD, Elana Kleinman

Oct 1st, 2021 - Juvenile xanthogranuloma (JXG) is a benign disorder presenting as firm, yellow-red skin papules or nodules, usually in infancy or early childhood. It derives its name based on its yellowish color and the histologic finding of lipid-filled histiocy.

Expert Offers Tips for Sorting Out Pink Lesions on Dermoscopy
https://www.medscape.com/viewarticle/945115

Feb 2nd, 2021 - Even in the most experienced hands, dermoscopy poses a challenge when the usual pigment clues are lacking to help distinguish melanoma from amelanotic melanoma and pigmented basal cell carcinoma (BCC) from nonpigmented BCC. Dr Jennifer Stein "For ...

Expert offers tips for sorting out pink lesions on dermoscopy
https://www.mdedge.com/dermatology/article/235239/melanoma/expert-offers-tips-sorting-out-pink-lesions-dermoscopy
Doug Brunk

Jan 29th, 2021 - Even in the most experienced hands, dermoscopy poses a challenge when the usual pigment clues are lacking to help distinguish melanoma from amelanotic melanoma and pigmented basal cell carcinoma (BCC) from nonpigmented BCC. Copyright Dr.

Solitary Papule on the Leg
https://www.mdedge.com/dermatology/article/207957/dermatopathology/solitary-papule-leg
Qiong Wu, MD, Daniel C. Skipper, DO et. al.

Sep 11th, 2019 - The Diagnosis: Epithelioid Histiocytoma Epithelioid histiocytoma (EH), also known as epithelioid cell histiocytoma or epithelioid fibrous histiocytoma, is a rare benign fibrohistiocytic tumor first described in 1989. 1 Epithelioid histiocytoma comm.

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