ALLMedicine™ Lymphomatoid Papulosis Center

Dec 20th, 2022 - The Study Drug: Brentuximab vedotin is an antibody that is designed to find a certain protein (called CD30) on cancer cells and bind to it. It is designed to then enter the cell and release a molecule that may kill the cancer cells. Study Drug Adm...

Nov 29th, 2022 - COVID-19 infection and vaccination may be associated with a wide variety of cutaneous and immune manifestations. Here, we describe two patients who presented with monoclonal cutaneous T-cell infiltrates that showed cytologic and immunophenotypic f...

Aug 24th, 2022 - Long-Term Monitoring Patients with a waxing and waning course of Mucha-Habermann disease require follow-up monitoring and additional treatment depending on the severity of the disease. The exact etiology of pityriasis lichenoides has yet to be elu...

Aug 9th, 2022 - Anaplastic large cell lymphoma (ALCL) can be classified genetically based on rearrangements (R) of the ALK , TP63 , and/or DUSP22 genes. ALK- R defines a specific entity, ALK-positive ALCL, while DUSP22- R and TP63- R define subgroups of ALK-negat...

Jul 31st, 2022 - Lymphomatoid papulosis (LYP), the most common primary cutaneous CD30-positive lymphoproliferative disorder, is heralded by multiple papular and nodular lesions at anatomically discontiguous cutaneous sites. The histologic patterns are protean. An ...

Dec 20th, 2022 - The Study Drug: Brentuximab vedotin is an antibody that is designed to find a certain protein (called CD30) on cancer cells and bind to it. It is designed to then enter the cell and release a molecule that may kill the cancer cells. Study Drug Adm...

Jul 16th, 2020 - This is an open label, Phase Ib/IIa study designed to evaluate the biologic activity of AFM13 in patients with relapsed or refractory CD30-positive lymphomas with cutaneous involvement. Primary cutaneous CD30-positive lymphoproliferative disorders...

Jun 29th, 2022 - The Diagnosis: Lymphomatoid Papulosis At the time of the initial visit, a punch biopsy was performed on the posterior shoulder girdle. Histopathology revealed mild epidermal spongiosis and acanthosis with associated parakeratosis and a dermal lymp.

Jun 14th, 2021 - The Diagnosis: Degos Disease The pathophysiology of Degos disease (malignant atrophic papulosis) is unknown. 1 Histopathology demonstrates a wedge-shaped area of dermal necrosis with edema and mucin deposition extending from the papillary dermis to.

May 24th, 2021 - To the Editor: Lymphomatoid papulosis (LyP) is a chronic, recurring, self-healing, primary cutaneous lymphoproliferative disorder. This disease affects patients of all ages but most commonly presents in the fifth decade with a slight male predomin.

May 11th, 2021 - The Diagnosis: Primary Cutaneous Anaplastic Large Cell Lymphoma Microscopic analysis showed a dense proliferation of mononuclear cells filling and expanding the dermis with focal epidermotropism (Figure 1). Immunohistochemistry demonstrated strong.

Jun 22nd, 2020 - To the Editor: Mycosis fungoides (MF) is the most common type of primary cutaneous lymphoma, occurring in approximately 4 of 1 million individuals per year in the United States. 1 It classically occurs in patch, plaque, and tumor stages with lesion.