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About 9,429 results

ALLMedicine™ Cutaneous Melanoma Center

Research & Reviews  4,561 results

Novel Prognostic Models Predicting the Cancer-Specific Survival in Patients with Cutane...
https://doi.org/10.1245/s10434-020-09556-6
Annals of Surgical Oncology; Li W, Xu X et. al.

Jan 12th, 2021 - In cutaneous melanoma (CM), the present methods of lymph node (LN) staging have not sufficiently utilized the prognostic information of metastatic LNs. In this study, we aimed to construct prognostic nomograms based on the number of positive LNs (...

Detrimental activation of AhR pathway in cancer: an overview of therapeutic strategies.
https://doi.org/10.1016/j.coi.2020.12.003
Current Opinion in Immunology; Leclerc D, Staats Pires AC et. al.

Jan 11th, 2021 - Sustained transcriptional activation of the aryl hydrocarbon receptor (AhR) promotes tumour growth and impairs the immune defence, at least for cutaneous melanoma and glioma. AhR ligands are produced by the tumour microenvironment (TME) and by the...

Differences in cutaneous melanoma survival between the 7th and 8th edition of the Ameri...
https://doi.org/10.1016/j.ejca.2020.11.036
European Journal of Cancer (Oxford, England : 1990); Barreiro-Capurro A, Andrés-Lencina JJ et. al.

Jan 8th, 2021 - The 8th edition of the AJCC manual for melanoma includes many changes leading to major substage migrations, which could lead to important clinical reassessments. To evaluate the differences and prognostic value of the 8th AJCC classification in co...

The Rapid Rise in Cutaneous Melanoma Diagnoses.
https://doi.org/10.1056/NEJMsb2019760
The New England Journal of Medicine; Welch HG, Mazer BL et. al.

Jan 6th, 2021 - The Rapid Rise in Cutaneous Melanoma Diagnoses.|2021|Welch HG,Mazer BL,Adamson AS,|

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Guidelines  27 results

Cutaneous Melanoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology
https://jnccn.org/view/journals/jnccn/17/4/article-p367.xml

Mar 31st, 2019 - For adjuvant treatment of melanoma in patients rendered free of disease by surgery, traditional systemic therapy approaches have proven to be ineffective. Adjuvant interferon alfa (IFN alfa), particularly high-dose IFN alfa, has been widely used i...

Guidelines of care for the management of primary cutaneous melanoma.
https://doi.org/10.1016/j.jaad.2018.08.055
Journal of the American Academy of Dermatology; Swetter SM, Tsao H et. al.

Nov 5th, 2018 - The incidence of primary cutaneous melanoma continues to increase each year. Melanoma accounts for the majority of skin cancer-related deaths, but treatment is usually curative following early detection of disease. In this American Academy of Derm...

An update on the Society for Immunotherapy of Cancer consensus statement on tumor immun...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977556
Journal for Immunotherapy of Cancer; Sullivan RJ, Atkins MB et. al.

May 31st, 2018 - Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and/or combination regimens for patien...

An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunother...
https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0362-6
Sullivan, R.

May 29th, 2018 - Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and/or combination regimens for patien.

New NCCN Guidelines for Uveal Melanoma and Treatment of Recurrent or Progressive Distan...
https://doi.org/10.6004/jnccn.2018.0042
Journal of the National Comprehensive Cancer Network : JNCCN; Barker CA, Salama AK

May 22nd, 2018 - The NCCN Guidelines Panel for Melanoma debuted new guidelines for uveal melanoma at the NCCN 23rd Annual Conference. Although uveal melanoma and cutaneous melanoma share the same name, they do have different characteristics and treatments. The NCC...

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Drugs  1 results see all →

Clinicaltrials.gov  4,699 results

Novel Prognostic Models Predicting the Cancer-Specific Survival in Patients with Cutane...
https://doi.org/10.1245/s10434-020-09556-6
Annals of Surgical Oncology; Li W, Xu X et. al.

Jan 12th, 2021 - In cutaneous melanoma (CM), the present methods of lymph node (LN) staging have not sufficiently utilized the prognostic information of metastatic LNs. In this study, we aimed to construct prognostic nomograms based on the number of positive LNs (...

Detrimental activation of AhR pathway in cancer: an overview of therapeutic strategies.
https://doi.org/10.1016/j.coi.2020.12.003
Current Opinion in Immunology; Leclerc D, Staats Pires AC et. al.

Jan 11th, 2021 - Sustained transcriptional activation of the aryl hydrocarbon receptor (AhR) promotes tumour growth and impairs the immune defence, at least for cutaneous melanoma and glioma. AhR ligands are produced by the tumour microenvironment (TME) and by the...

Differences in cutaneous melanoma survival between the 7th and 8th edition of the Ameri...
https://doi.org/10.1016/j.ejca.2020.11.036
European Journal of Cancer (Oxford, England : 1990); Barreiro-Capurro A, Andrés-Lencina JJ et. al.

Jan 8th, 2021 - The 8th edition of the AJCC manual for melanoma includes many changes leading to major substage migrations, which could lead to important clinical reassessments. To evaluate the differences and prognostic value of the 8th AJCC classification in co...

The Rapid Rise in Cutaneous Melanoma Diagnoses.
https://doi.org/10.1056/NEJMsb2019760
The New England Journal of Medicine; Welch HG, Mazer BL et. al.

Jan 6th, 2021 - The Rapid Rise in Cutaneous Melanoma Diagnoses.|2021|Welch HG,Mazer BL,Adamson AS,|

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News  141 results

Mohs Surgery May Not Boost Survival Over Standard Excision of Melanomas on Trunk, Extremities
https://www.medscape.com/viewarticle/940003

Oct 29th, 2020 - NEW YORK (Reuters Health) - Compared with wide local excision (WLE), Mohs micrographic surgery (MMS) does not appear to increase overall survival in patients with trunk or extremity melanomas, according to a retrospective study. "In contrast to ou...

Melanoma Patients Still at Higher Risk for New Malignancy After Successful Systemic Immunotherapy
https://www.medscape.com/viewarticle/938007

Sep 24th, 2020 - NEW YORK (Reuters Health) - Patients successfully treated for metastatic melanoma with immune-checkpoint inhibitors remain at increased risk for developing new primary cutaneous melanoma, according to a new study. "The 5-year risk was nearly 5%," ...

Melanoma Patients Still at Higher Risk for New Malignancy After Successful Systemic Immunotherapy
https://www.staging.medscape.com/viewarticle/938007

Sep 24th, 2020 - NEW YORK (Reuters Health) - Patients successfully treated for metastatic melanoma with immune-checkpoint inhibitors remain at increased risk for developing new primary cutaneous melanoma, according to a new study. "The 5-year risk was nearly 5%," ...

Melanoma Experts Say 'No' to Routine Gene Profile Testing
https://www.medscape.com/viewarticle/936364

Aug 25th, 2020 - An international panel of 49 melanoma specialists has come out against routine gene expression profile (GEP) testing for cutaneous melanoma, pending solid proof of clinical benefit. "The currently published evidence is insufficient to establish th...

Fast Five Quiz: Malignant Melanoma
https://reference.medscape.com/viewarticle/936083_4

Aug 20th, 2020 - Four major clinicopathologic subtypes of primary cutaneous melanoma have been identified, although newer classifications of melanoma include location on chronically sun-exposed vs intermittently or non–sun-exposed skin and incorporate the presence...

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