ALLMedicine™ Liposarcoma Center
Research & Reviews 796 results
Advances in Anatomic Pathology; Kilpatrick SE
Jul 31st, 2021 - Among all sarcoma types, liposarcoma is the most common sarcoma that develops "dedifferentiation." Since its initial description by Dr Harry Evans, the spectrum of what is now acceptably included under the rubric of "dedifferentiated liposarcoma" ...
Pathology, Research and Practice; Kuczkiewicz-Siemion O, Wiśniewski P et. al.
Jul 30th, 2021 - Dedifferentiated liposarcoma (DDLPS) is characterized by non-lipogenic sarcoma fields coexisting with adipocyte-rich well-differentiated areas. Amplification of the 12q13-15 region includes the MDM2 and DDIT3 genes. MDM2 amplification is considere...
BMJ Case Reports; Fra MC, Brenna M et. al.
Jul 25th, 2021 - A male patient, aged over 75 years, was referred to the emergency room for pain in his right hypochondrium. This pain, which persisted for approximately 3 days, radiated to his right flank and right iliac quadrant and worsened after meals. The pat...
BMJ Case Reports; Sanchez-Sancho P, Selva-O'Callaghan A et. al.
Jul 23rd, 2021 - This case report concerns a 63-year-old man affected by metastatic undifferentiated liposarcoma. After receiving pembrolizumab as a second-line treatment in a clinical trial, the patient experienced an immune-mediated myocarditis, myositis and mya...
BMJ Case Reports; Singh BK, Pol MM et. al.
Jul 22nd, 2021 - A 52-year-old man presented with a recurrent right side breast lump. He had undergone excision of a lump on the right breast followed by adjuvant chemoradiotherapy 1 year ago for a diagnosis of pleomorphic liposarcoma. Imaging revealed a 47×36 mm ...
Drugs 9 results see all →
Clinicaltrials.gov 25 results
Mar 4th, 2020 - PRIMARY OBJECTIVES: I. To assess the pathologic response of nivolumab monotherapy and nivolumab and ipilimumab combination therapy administered in the neoadjuvant setting with and without radiation in patients with treatment-naive primary or local...
Feb 19th, 2020 - PRIMARY OBJECTIVE: I. To determine the recommended phase 2 dose (RP2D) of radiation and eribulin mesylate (eribulin) when used in combination for the preoperative treatment of retroperitoneal liposarcoma. SECONDARY OBJECTIVES: I. To assess the fea...
Nov 21st, 2018 - Liposarcomas are the most common type of soft tissue sarcomas (STS). Among liposarcomas, well-differentiated liposarcoma (WDLPS)/dedifferentiated liposarcoma (DDLPS) are the most frequent types. WDLPS are composed mostly of mature fat whereas DDLP...
Nov 1st, 2018 - In the Phase 2 portion of the study, 57 patients were randomized to selinexor (60 mg) or placebo at a 1:1 allocation ratio. In the Phase 3 portion of the study, approximately 222 patients will be randomized to selinexor (60 mg) or placebo with a 2...
Oct 19th, 2018 - This study will investigate the safety and tolerability of MAGE-A4ᶜ¹º³²T cell therapy in subjects who have the appropriate HLA-A2 tissue marker and whose urinary bladder, melanoma, head and neck, ovarian, non-small cell lung, esophageal, gastric, ...
News 41 results
Nov 17th, 2020 - De-intensification of preoperative radiation therapy is both effective and oncologically safe in patients with myxoid liposarcoma, an extremely rare type of soft tissue sarcoma (STS). The lower doses of radiotherapy were also associated with far l...
William D. Tap, MD
Sep 17th, 2019 - In this issue of The Sarcoma Journal , we highlight research and developments presented at the 2019 ASCO annual meeting. Despite the rarity of sarcoma, it was not lost among the thousands of abstracts, posters, and talks presented during the four-.
Dickan A, Gootee J et. al.
Sep 9th, 2019 - Background: Myxoid liposarcomas (MLS) are intermediate to high grade liposarcomas, which are the most common type of soft tissue sarcoma. Although MLS most frequently develops in the legs, it can arise in any of the body’s soft tissue adipose.
Lee HG, Aurit S et. al.
Sep 9th, 2019 - Background: Pleomorphic liposarcomas is an aggressive, high grade subtype of soft tissue sarcoma representing < 15% of liposarcomas. It most commonly arises in the retroperitoneum and proximal upper extremities.
Nguyen K, Gootee J et. al.
Sep 5th, 2019 - Background: Liposarcoma is the most common malignant soft tissue sarcoma (STS). Surgical resection is the most utilized therapeutic option.