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About 14,834 results

ALLMedicine™ Malignant Melanoma Center

Research & Reviews  7,147 results

Melanoma Arising From a Pre-existing Neurofibroma in a Patient With No Prior Diagnosis ...
https://doi.org/10.1097/DAD.0000000000001888
The American Journal of Dermatopathology; Nasir W, Howard T et. al.

Jan 19th, 2021 - The pathophysiology of melanoma involves malignant transformation of melanocytes. These can arise de novo or result from malignant transformation of a pre-existing nevus. This case report presents a patient with a new pigmented lesion, arising fro...

Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: treatment of melanoma and immun...
https://doi.org/10.1002/eji.202048747
European Journal of Immunology; Willsmore ZN, Coumbe BGT et. al.

Jan 15th, 2021 - Cytotoxic T-lymphocyte associated protein-4 (CTLA-4) and the Programmed Death Receptor 1 (PD-1) are immune checkpoint molecules that are well-established targets of antibody immunotherapies for the management of malignant melanoma. The monoclonal ...

Immune signature as predictive marker for response to checkpoint inhibitor immunotherap...
https://doi.org/10.1002/cam4.3710
Cancer Medicine REFERENCES; Krebs FK, Trzeciak ER et. al.

Jan 15th, 2021 - Malignant melanoma is an immunogenic skin cancer with an increasing global incidence. Advanced stages of melanoma have poor prognoses. Currently, there are no reliable parameters to predict a patient's response to immune checkpoint inhibitor (ICI)...

High TRAF3IP3 level predicts poor prognosis of patients with gliomas.
https://doi.org/10.1016/j.wneu.2021.01.006
World Neurosurgery; Yang G, Tang S et. al.

Jan 14th, 2021 - Tumor necrosis factor receptor-related factor 3 (TRAF3) interacting protein 3 (TRAF3IP3) is involved in the development of immune tissues and the immune response of the body. Down-regulated expression of TRAF3IP3 in malignant melanoma can inhibit ...

Immunotherapy-related pneumonitis and bacterial pneumonia after the successful treatmen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793440
Medicine Ma Q, Yang L et. al.

Jan 12th, 2021 - Pembrolizumab, a monoclonal antibody targeting programmed cell death-1 (PD-1), is approved as a therapy for unresectable or metastatic melanoma. Immunotherapy-associated pneumonitis is an uncommon event. A 73-year-old man was admitted to our hospi...

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Guidelines  15 results

An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunother...
https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0362-6
Sullivan, R.

May 29th, 2018 - Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and/or combination regimens for patien.

Behavioral Counseling to Prevent Skin Cancer
https://jamanetwork.com/journals/jama/fullarticle/2675556
David C. Grossman

May 19th, 2018 - Skin cancer is the most common type of cancer in the United States. Although invasive melanoma accounts for only 2% of all skin cancer cases, it is responsible for 80% of skin cancer deaths.

Skin Cancer Prevention: Behavioral Counseling
https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/skin-cancer-counseling2
US Preventive Services Task Force

Mar 30th, 2018 - The USPSTF recommends counseling young adults, adolescents, children, and parents of young children about minimizing exposure to ultraviolet (UV) radiation for persons aged 6 months to 24 years with fair skin types to reduce their risk of skin can.

Sentinel Lymph Node Biopsy for Melanoma
http://ascopubs.org/doi/full/10.1200/JCO.2017.75.7724
Sandra L. Wong

Jan 31st, 2018 - To update the American Society of Clinical Oncology (ASCO)-Society of Surgical Oncology (SSO) guideline for sentinel lymph node (SLN) biopsy in melanoma.

SEOM clinical guideline for the management of malignant melanoma (2017).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785602
Clinical & Translational Oncology : Official Publication ... Berrocal A, Arance A et. al.

Nov 8th, 2017 - All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon could be offered for patients with high-ri...

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Drugs  7 results see all →

Clinicaltrials.gov  7,371 results

Melanoma Arising From a Pre-existing Neurofibroma in a Patient With No Prior Diagnosis ...
https://doi.org/10.1097/DAD.0000000000001888
The American Journal of Dermatopathology; Nasir W, Howard T et. al.

Jan 19th, 2021 - The pathophysiology of melanoma involves malignant transformation of melanocytes. These can arise de novo or result from malignant transformation of a pre-existing nevus. This case report presents a patient with a new pigmented lesion, arising fro...

Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: treatment of melanoma and immun...
https://doi.org/10.1002/eji.202048747
European Journal of Immunology; Willsmore ZN, Coumbe BGT et. al.

Jan 15th, 2021 - Cytotoxic T-lymphocyte associated protein-4 (CTLA-4) and the Programmed Death Receptor 1 (PD-1) are immune checkpoint molecules that are well-established targets of antibody immunotherapies for the management of malignant melanoma. The monoclonal ...

Immune signature as predictive marker for response to checkpoint inhibitor immunotherap...
https://doi.org/10.1002/cam4.3710
Cancer Medicine REFERENCES; Krebs FK, Trzeciak ER et. al.

Jan 15th, 2021 - Malignant melanoma is an immunogenic skin cancer with an increasing global incidence. Advanced stages of melanoma have poor prognoses. Currently, there are no reliable parameters to predict a patient's response to immune checkpoint inhibitor (ICI)...

High TRAF3IP3 level predicts poor prognosis of patients with gliomas.
https://doi.org/10.1016/j.wneu.2021.01.006
World Neurosurgery; Yang G, Tang S et. al.

Jan 14th, 2021 - Tumor necrosis factor receptor-related factor 3 (TRAF3) interacting protein 3 (TRAF3IP3) is involved in the development of immune tissues and the immune response of the body. Down-regulated expression of TRAF3IP3 in malignant melanoma can inhibit ...

Immunotherapy-related pneumonitis and bacterial pneumonia after the successful treatmen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7793440
Medicine Ma Q, Yang L et. al.

Jan 12th, 2021 - Pembrolizumab, a monoclonal antibody targeting programmed cell death-1 (PD-1), is approved as a therapy for unresectable or metastatic melanoma. Immunotherapy-associated pneumonitis is an uncommon event. A 73-year-old man was admitted to our hospi...

see more →

News  293 results

ICI for Cancer Ups Cardiac Event Risk: Danish Data
https://www.medscape.com/viewarticle/943003

Dec 20th, 2020 - Immune checkpoint inhibitors (ICIs) increase the risk of cardiac events, including fatal heart attack and stroke, in patients with cancer, an analysis of Danish national registry data suggests. About 10% of 743 registry participants with lung canc...

Quiz: Test Your Knowledge on Cancer Referrals for Children and Young Adults
https://www.medscape.com/viewarticle/939423_5

Oct 21st, 2020 - A person with suspected malignant melanoma should be referred for an appointment within 2 weeks using a suspected cancer pathway if they have a suspicious pigmented skin lesion with a weighted 7-point checklist score of: Your Peers Chose: 5 or mor...

Fast Five Quiz: Malignant Melanoma
https://reference.staging.medscape.com/viewarticle/936083_1

Aug 20th, 2020 - A melanoma is a tumor produced by the malignant transformation of melanocytes and is most commonly cutaneous. Although melanoma accounts for a very small percentage of all skin cancers, it is responsible for the most skin cancer-related deaths. Th...

Fast Five Quiz: Malignant Melanoma
https://reference.medscape.com/viewarticle/936083_4

Aug 20th, 2020 - Four major clinicopathologic subtypes of primary cutaneous melanoma have been identified, although newer classifications of melanoma include location on chronically sun-exposed vs intermittently or non–sun-exposed skin and incorporate the presence...

Fast Five Quiz: Malignant Melanoma
https://reference.medscape.com/viewarticle/936083_6

Aug 20th, 2020 - Current guidelines from the AAD on the evaluation and management of primary cutaneous melanoma include: Evidence strongly indicates that Breslow thickness, ulceration, and dermal mitotic rate are important predictors of patient outcome in primary ...

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Patient Education  1 results see all →