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About 14,534 results

ALLMedicine Malignant Melanoma Center

Research & Reviews  6,891 results

Primary malignant melanoma of the esophagus with multiple lymph node metastases: A case...
https://doi.org/10.1097/MD.0000000000018573
Medicine Iwasaki K, Ota Y et. al.

Jun 1st, 2020 - Primary malignant melanoma of the esophagus (PMME) is a very rare malignancy accounting for only 0.1% to 0.2% of all malignant esophageal lesions. Presently, there are no standard strategies or clear guidelines for PMME treatment. Herein, we repor...

Ocular side effects of target therapy and immunotherapy in patients with cutaneous mali...
https://doi.org/10.1177/1120672120930688
European Journal of Ophthalmology; Eikenberry J, Harris A et. al.

May 30th, 2020 - To examine the nature and frequency of ocular side effects due to systemic target therapy with BRAF and MEK inhibitors as well as immunotherapy with cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) monoclonal antibodies...

RAC1 as a Therapeutic Target in Malignant Melanoma.
https://doi.org/10.1016/j.trecan.2020.02.021
Trends in Cancer; Cannon AC, Uribe-Alvarez C et. al.

May 27th, 2020 - Small GTPases of the RAS and RHO families are related signaling proteins that, when activated by growth factors or by mutation, drive oncogenic processes. While activating mutations in KRAS, NRAS, and HRAS genes have long been recognized and occur...

Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant me...
https://doi.org/10.1186/s13046-020-01599-7
Journal of Experimental & Clinical Cancer Research : CR; Luan W, Ding Y et. al.

May 27th, 2020 - Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecular mechanism of LINC00520 in malignan...

The association between smoking and risk of skin cancer: a meta-analysis of cohort stud...
https://doi.org/10.1007/s10552-020-01319-8
Cancer Causes & Control : CCC; Arafa A, Mostafa A et. al.

May 26th, 2020 - The association between smoking and the risk of skin cancers has been studied without reaching consistent findings. This study aims to assess this association through an updated meta-analysis of cohort studies. We retrieved cohort studies that inv...

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Guidelines  15 results

An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunother...
https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0362-6
Sullivan, R.

May 29th, 2018 - Cancer immunotherapy has been firmly established as a standard of care for patients with advanced and metastatic melanoma. Therapeutic outcomes in clinical trials have resulted in the approval of 11 new drugs and/or combination regimens for patien.

Behavioral Counseling to Prevent Skin Cancer
https://jamanetwork.com/journals/jama/fullarticle/2675556
David C. Grossman

May 19th, 2018 - Skin cancer is the most common type of cancer in the United States. Although invasive melanoma accounts for only 2% of all skin cancer cases, it is responsible for 80% of skin cancer deaths.

Skin Cancer Prevention: Behavioral Counseling
https://www.uspreventiveservicestaskforce.org/Page/Document/UpdateSummaryFinal/skin-cancer-counseling2
US Preventive Services Task Force

Mar 30th, 2018 - The USPSTF recommends counseling young adults, adolescents, children, and parents of young children about minimizing exposure to ultraviolet (UV) radiation for persons aged 6 months to 24 years with fair skin types to reduce their risk of skin can.

Sentinel Lymph Node Biopsy for Melanoma
http://ascopubs.org/doi/full/10.1200/JCO.2017.75.7724
Sandra L. Wong

Jan 31st, 2018 - To update the American Society of Clinical Oncology (ASCO)-Society of Surgical Oncology (SSO) guideline for sentinel lymph node (SLN) biopsy in melanoma.

SEOM clinical guideline for the management of malignant melanoma (2017).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785602
Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico; Berrocal A, Arance A et. al.

Nov 8th, 2017 - All melanoma suspected patients must be confirmed histologically and resected. Sentinel node biopsy must be done when tumor is over 1 mm or if less with high-risk factors. Adjuvant therapy with interferon could be offered for patients with high-ri...

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Drugs  7 results see all →

Clinicaltrials.gov  7,221 results

Primary malignant melanoma of the esophagus with multiple lymph node metastases: A case...
https://doi.org/10.1097/MD.0000000000018573
Medicine Iwasaki K, Ota Y et. al.

Jun 1st, 2020 - Primary malignant melanoma of the esophagus (PMME) is a very rare malignancy accounting for only 0.1% to 0.2% of all malignant esophageal lesions. Presently, there are no standard strategies or clear guidelines for PMME treatment. Herein, we repor...

Ocular side effects of target therapy and immunotherapy in patients with cutaneous mali...
https://doi.org/10.1177/1120672120930688
European Journal of Ophthalmology; Eikenberry J, Harris A et. al.

May 30th, 2020 - To examine the nature and frequency of ocular side effects due to systemic target therapy with BRAF and MEK inhibitors as well as immunotherapy with cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) monoclonal antibodies...

RAC1 as a Therapeutic Target in Malignant Melanoma.
https://doi.org/10.1016/j.trecan.2020.02.021
Trends in Cancer; Cannon AC, Uribe-Alvarez C et. al.

May 27th, 2020 - Small GTPases of the RAS and RHO families are related signaling proteins that, when activated by growth factors or by mutation, drive oncogenic processes. While activating mutations in KRAS, NRAS, and HRAS genes have long been recognized and occur...

Long non-coding RNA LINC00520 promotes the proliferation and metastasis of malignant me...
https://doi.org/10.1186/s13046-020-01599-7
Journal of Experimental & Clinical Cancer Research : CR; Luan W, Ding Y et. al.

May 27th, 2020 - Long intergenic non-protein coding RNA 520 (LINC00520), a novel identified lncRNA, has been shown to modulate the malignant phenotype of tumor cells in some malignant tumors. However, the exact role and molecular mechanism of LINC00520 in malignan...

The association between smoking and risk of skin cancer: a meta-analysis of cohort stud...
https://doi.org/10.1007/s10552-020-01319-8
Cancer Causes & Control : CCC; Arafa A, Mostafa A et. al.

May 26th, 2020 - The association between smoking and the risk of skin cancers has been studied without reaching consistent findings. This study aims to assess this association through an updated meta-analysis of cohort studies. We retrieved cohort studies that inv...

see more →

News  399 results

Fast Five Quiz: How Much Do You Know About Melanomas?
https://www.medscape.com/viewarticle/882100

Feb 17th, 2020 - Malignant melanoma is a neoplasm of melanocytes or a neoplasm of the cells that develop from melanocytes. Melanocytes are derived from the neural crest; consequently, although they usually occur on the skin, melanomas can arise in other locations ...

Fast Five Quiz: Melanoma Treatment
https://www.medscape.com/viewarticle/919200

Jan 23rd, 2020 - In the past 50 years, the incidence of malignant melanoma, a potentially lethal skin cancer, has increased dramatically around the world, faster than any other type of cancer. Melanoma is most frequently seen in geriatric populations, but it is al...

Urethral Involvement Key in Vulvar Melanoma Recurrence
https://www.medscape.com/viewarticle/920404

Oct 24th, 2019 - Urethral involvement has been singled out for the first time as a key factor in the risk for recurrence in women with vulvar malignant melanoma, an observational study indicates. That and tumor depth are the key features that predict time to death...

Sniffing Out Malignant Melanoma: A Case of Canine Olfactory Detection
https://www.mdedge.com/dermatology/article/207845/melanoma/sniffing-out-malignant-melanoma-case-canine-olfactory-detection?channel=44
Radhika Srivastava, BA, Jason J. John, BS et. al.

Sep 10th, 2019 - To the Editor: A 43-year-old woman presented with a mole on the central back that had been present since childhood and had changed and grown over the last few years. The patient reported that her 2-year-old rescue dog frequently sniffed the mole a.

Melanoma of Unknown Primary Presenting as a Parotid Gland Mass
https://www.mdedge.com/fedprac/avaho/article/207548/melanoma/melanoma-unknown-primary-presenting-parotid-gland-mass?channel=53
Kerrigan K, Khansur E et. al.

Sep 4th, 2019 - Background: Malignant melanoma is an aggressive malignancy that can present as a poorly differentiated neoplasm. Loss of S100 and melanA antigenicity can make pathologic identification difficult, especially in those patients who lack a cutaneous p.

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Patient Education  1 results see all →