ALLMedicine™ Lentigo Maligna Melanoma Center

Jan 16th, 2022 - In their article in the Journal of Investigative Dermatology, Conway et al. (2021) show the significance of the CpG island methylator phenotype (CIMP) subclass in early-stage invasive primary melanomas, particularly in the lentigo maligna melanoma...

Dec 8th, 2021 - Practice Essentials A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin (see the image below), can arise in ...

Dec 8th, 2021 - A melanoma is a tumor produced by the malignant transformation of melanocytes. Melanocytes are derived from the neural crest; consequently, melanomas, although they usually occur on the skin (see the image below), can arise in other locations wher...

Oct 8th, 2021 - Heat shock proteins can protect against stress-associated cellular challenges, but they can also protect some tumors from human immune system monitoring. Heat shock protein 105 (HSP105/110) is a high molecular weight protein whose expression has b...

Sep 11th, 2021 - Lentigo maligna (LM) is a melanocytic neoplasm found on chronically sun-exposed areas of the body, particularly the head and neck. It commonly occurs in the elderly and has been referred to as a "senile freckle." It has also been termed "Hutchinso...

Oct 23rd, 2019 - Lentigo maligna (LM) is a subtype of melanoma in situ that usually occurs in sun-damaged skin and is characterised by an atypical proliferation of melanocytes within the basal epidermis. If left untreated, LM can develop into invasive melanoma, te...

Sep 25th, 2019 - Mohs micrographic surgery was associated with improved survival compared with traditional excision in early invasive melanoma, a retrospective study indicated. Among more than 70,000 stage I patients in a national database, univariable analysis sh...

Mar 7th, 2019 - The FP suspected that this was a skin cancer with ulceration and pigmentation. The differential diagnosis included pigmented basal cell carcinoma, melanoma, and squamous cell carcinoma.

Feb 28th, 2019 - The FP was concerned that this could be melanoma. He used his dermatoscope and saw suspicious patterns that included polygonal lines and circle-within-circle patterns.

Jun 2nd, 2015 - The four major types of melanoma, classified according to growth pattern, are: Superficial spreading melanoma. Constitutes approximately 70% of melanomas; usually flat but may become irregular and elevated in later stages; the lesions average 2 cm...

Jan 14th, 2011 - ORLANDO - Standard surgical margins often are inadequate for lentigo maligna; instead, perimeter excision techniques or Mohs surgery is preferable because these approaches consistently provide high cure rates, according to Dr. Basil S.