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About 72,878 results

ALLMedicine™ Squamous Cell Carcinoma Center

Research & Reviews  25,822 results

When cisplatin won’t do, try carboplatin in head and neck cancer
https://www.mdedge.com/hematology-oncology/article/258480/head-neck/thyroid-cancers/when-cisplatin-wont-do-try-carboplatin
Jim Kling

Oct 6th, 2022 - Among patients with locally advanced head and neck squamous cell carcinoma who are ineligible to receive cisplatin, carboplatin-based chemoradiotherapy (CRT) may be a better option than cetuximab-based chemoradiotherapy, according to a new cohort.

Role of sentinel lymph node biopsy for oral squamous cell carcinoma: Current evidence a...
https://doi.org/10.1002/hed.27207
Head & Neck; Jang SS, Davis ME et. al.

Oct 5th, 2022 - Sentinel lymph node biopsy (SLNB) has been used across oncological specialties for prognostication, staging, and identification of occult nodal metastasis. Recent studies demonstrated the potential clinical utility of SLNB in oral cavity squamous ...

G2 and S phase-expressed-1 induces chromosomal instability in esophageal squamous cell ...
https://doi.org/10.1002/mc.23470
Molecular Carcinogenesis; Zhang M, Wang X et. al.

Oct 5th, 2022 - New diagnostic and therapeutic strategies are urgently needed to improve the prognosis of patients with esophageal squamous cell carcinoma (ESCC), which has high morbidity and mortality. Bioinformatics analysis revealed that cell cycle regulation ...

Clinical Implications and Management of Non-ALCL Breast Implant Capsular Pathology.
https://doi.org/10.1097/PRS.0000000000009780
Plastic and Reconstructive Surgery; Vorstenbosch J, Chu JJ et. al.

Oct 5th, 2022 - The breast implant capsule is a dynamic structure that forms following the implantation of a device. Although normally benign, increased awareness of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) highlights that disease may a...

Squamous Cell Carcinoma of Skin Cancer Margin Classification From Digital Histopatholog...
https://doi.org/10.1177/10732748221132528
Cancer Control : Journal of the Moffitt Cancer Center; Wako BD, Dese K et. al.

Oct 5th, 2022 - Now a days, squamous cell carcinoma (SCC) margin assessment is done by examining histopathology images and inspection of whole slide images (WSI) using a conventional microscope. This is time-consuming, tedious, and depends on experts' experience ...

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Guidelines  37 results

ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT...
https://doi.org/10.1016/j.prro.2022.01.015
Practical Radiation Oncology; Damico N, Meyer J et. al.

Jun 19th, 2022 - Previous anal cancer guidelines delineate target volumes similarly for all patients with squamous cell carcinoma of the anal canal and/or perianal skin (SCCA), regardless of disease stage. The purpose of this guideline is to provide customized rad...

Clinical features, molecular characteristics and surgical management of primary penile ...
https://doi.org/10.1097/CMR.0000000000000788
Melanoma Research; Cakir OO, Pozzi E et. al.

Nov 30th, 2021 - Penile mucosal melanoma is an aggressive and rare genital malignancy. The aim of the present study was to review the management and outcomes of a homogenous cohort of patients with histologically confirmed penile mucosal melanoma, at a single spec...

Poor tumor differentiation is an independent adverse prognostic variable in patients wi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495291
Cancer Medicine; Lee LY, Lin CY et. al.

Sep 18th, 2021 - We sought to compare the prognostic impact of tumor differentiation with respect to adverse risk factors (RFs) identified by the National Comprehensive Cancer Network (NCCN) guidelines--including extranodal extension (ENE), positive/close margins,...

ACR Appropriateness Criteria® Staging and Follow-up of Vulvar Cancer.
https://doi.org/10.1016/j.jacr.2021.02.016
Journal of the American College of Radiology : JACR; , Lakhman Y et. al.

May 8th, 2021 - Vulvar cancer is an uncommon gynecologic tumor and one of several human papillomavirus-associated malignancies. Squamous cell carcinoma is the most prevalent histologic subtype of vulvar cancer, accounting for the majority of cases. Imaging plays ...

Summary of the updated 2020 guidelines for cutaneous squamous cell carcinoma.
https://doi.org/10.1111/ced.14587
Clinical and Experimental Dermatology; Woo WA, Suarez M-Falero B et. al.

Mar 18th, 2021 - Summary of the updated 2020 guidelines for cutaneous squamous cell carcinoma.|2021|Woo WA,Suarez M-Falero B,Keohane SG,|pathology,therapy,pathology,therapy,

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Drugs  60 results see all →

Clinicaltrials.gov  1,859 results

Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer
https://clinicaltrials.gov/ct2/show/NCT04915183

Sep 30th, 2022 - Study Description: Individuals undergoing cisplatin-based chemoradiation therapy are at risk for developing significant, permanent hearing loss. The cholesterol-lowering drug atorvastatin has the potential to reduce the incidence and severity of h...

A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradio...
https://clinicaltrials.gov/ct2/show/NCT04543617

Sep 30th, 2022 - The purpose of this study is to evaluate the efficacy and safety of tiragolumab plus atezolizumab compared with placebo in participants with unresectable esophageal squamous cell carcinoma (or those who are unable or unwilling to undergo surgery) ...

Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell Carcinoma
https://clinicaltrials.gov/ct2/show/NCT03803774

Sep 30th, 2022 - PRIMARY OBJECTIVE: I. Determine the toxicities and maximum tolerated dose (MTD) of birinapant concurrent with intensity modulated re-irradiation therapy (IMRRT). SECONDARY OBJECTIVES: I. Determine the objective response rate of patients with locor...

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Added to Radiation or Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent H...
https://clinicaltrials.gov/ct2/show/NCT04671667

Sep 30th, 2022 - PRIMARY OBJECTIVES: I. To evaluate overall survival (OS) of adjuvant reirradiation plus concurrent pembrolizumab followed by pembrolizumab to complete 12 months total of pembrolizumab to adjuvant reirradiation plus concurrent platinum chemotherapy...

Study of Magrolimab Combination Therapy in Participants With Head and Neck Squamous Cell Carcinoma
https://clinicaltrials.gov/ct2/show/NCT04854499

Sep 30th, 2022 - The study consists of Safety Run-in and Phase 2 Cohorts. The primary objectives of the safety run-in cohorts of this study are to evaluate the safety, tolerability, and recommended Phase 2 dose (RP2D) of magrolimab in combination with pembrolizuma...

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News  1,355 results

When cisplatin won’t do, try carboplatin in head and neck cancer
https://www.mdedge.com/hematology-oncology/article/258480/head-neck/thyroid-cancers/when-cisplatin-wont-do-try-carboplatin
Jim Kling

Oct 6th, 2022 - Among patients with locally advanced head and neck squamous cell carcinoma who are ineligible to receive cisplatin, carboplatin-based chemoradiotherapy (CRT) may be a better option than cetuximab-based chemoradiotherapy, according to a new cohort.

Image-Guided Superficial Radiation as First-line in Skin Cancer?
https://www.medscape.com/viewarticle/981722

Sep 30th, 2022 - The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaway Absolute lesion control rate with image-guided superficial radiation therapy (IGSRT) for early-stage non-melanoma skin ca...

Fast growing hand lesion
https://www.mdedge.com/familymedicine/article/258275/dermatology/fast-growing-hand-lesion
MDedge Family Medicine;

Sep 28th, 2022 - A scoop shave biopsy at the lower edge of the lesion revealed that this was a well-differentiated squamous cell carcinoma. Squamous cell carcinoma is the second most common cancer in the United States and the most common skin cancer in Black peopl.

Neoadjuvant immunotherapy shows promise for resectable CSCC
https://www.mdedge.com/hematology-oncology/article/258241/head-neck/thyroid-cancers/neoadjuvant-immunotherapy-shows-promise
Jim Kling

Sep 27th, 2022 - Neoadjuvant immunotherapy for stage II-IV cutaneous squamous cell carcinoma (CSCC) led to a strong pathological complete response rate, according to results from a stage 2 clinical trial. CSCC hasn’t received much attention from pharmaceutical com.

Neoadjuvant Immunotherapy Shows Promise for Resectable CSCC
https://www.medscape.com/viewarticle/981530

Sep 27th, 2022 - Neoadjuvant immunotherapy for stage II-IV cutaneous squamous cell carcinoma (CSCC) led to a strong pathological complete response rate, according to results from a stage 2 clinical trial. CSCC hasn't received much attention from pharmaceutical com...

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Patient Education  18 results see all →