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About 120,056 results

ALLMedicine Melanoma Center

Research & Reviews  55,145 results

Reflectance confocal microscopy terminology glossary for melanocytic skin lesions: A sy...
https://doi.org/10.1016/j.jaad.2020.05.097
Journal of the American Academy of Dermatology; Navarrete-Dechent C, Liopyris K et. al.

May 26th, 2020 - There is lack of uniformity in the reflectance confocal microscopy (RCM) terminology for melanocytic lesions. To review published RCM terms for melanocytic lesions and identify redundant, synonymous terms. Systematic review of original research ar...

The EORTC-DeCOG nomogram adequately predicts outcomes of patients with sentinel node-po...
https://doi.org/10.1016/j.ejca.2020.04.022
European Journal of Cancer (Oxford, England : 1990); Verver D, Rekkas A et. al.

May 26th, 2020 - Based on recent advances in the management of patients with sentinel node (SN)-positive melanoma, we aimed to develop prediction models for recurrence, distant metastasis (DM) and overall mortality (OM). The derivation cohort consisted of 1080 pat...

In-depth plasma proteomics reveals increase in circulating PD-1 during anti-PD-1 immuno...
https://doi.org/10.1136/jitc-2019-000204
Journal for Immunotherapy of Cancer; Babačić H, Lehtiö J et. al.

May 26th, 2020 - Immune checkpoint inhibitors (ICIs) have significantly improved the outcome in metastatic cutaneous melanoma (CM). However, therapy response is limited to subgroups of patients and clinically useful predictive biomarkers are lacking. To discover t...

RHPN1-AS1 promotes cell proliferation and migration via miR-665/Akt3 in ovarian cancer.
https://doi.org/10.1038/s41417-020-0180-0
Cancer Gene Therapy; Zhao J, Yang T et. al.

May 26th, 2020 - Recent efforts have revealed that long non-coding RNAs exert crucial roles in cancer initiation and progression. RHPN1-AS1 is a 2030 bp transcript from human chromosome 8q24, and involved in tumorigenesis in uveal melanoma and non-small cell lung ...

The association between smoking and risk of skin cancer: a meta-analysis of cohort stud...
https://doi.org/10.1007/s10552-020-01319-8
Cancer Causes & Control : CCC; Arafa A, Mostafa A et. al.

May 26th, 2020 - The association between smoking and the risk of skin cancers has been studied without reaching consistent findings. This study aims to assess this association through an updated meta-analysis of cohort studies. We retrieved cohort studies that inv...

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Guidelines  145 results

High-dose vitamin C enhances cancer immunotherapy
https://stm.sciencemag.org/content/12/532/eaay8707
Science Translational Medicine; Magri A,et al

Feb 19th, 2020 - Vitamin C (VitC) is known to directly impair cancer cell growth in preclinical models, but there is little clinical evidence on its antitumoral efficacy. In addition, whether and how VitC modulates anticancer immune responses is mostly unknown. He...

Accuracy of Dermoscopy vs. Visual Inspection for Diagnosing Melanoma in Adults
https://www.aafp.org/afp/2020/0201/p145.html
American Family Physician; Clebak KT,et al

Jan 31st, 2020 - The addition of dermoscopy to in-person visual inspection of skin lesions increases specificity and sensitivity in the detection of melanoma. In-person evaluation with dermoscopy is more accurate than image-based assessment. A published algorithm ...

Some melanomas may start in hair follicles
https://www.nih.gov/news-events/nih-research-matters/some-melanomas-may-start-hair-follicles
NIH

Nov 30th, 2019 - A rare form of skin cancer may sometimes start with cancer-causing mutations in hair follicle stem cells. A better understanding of how melanoma arises may lead to ways to detect and treat the disease earlier.

The impact of systemic precision medicine and immunotherapy treatments on brain metastases
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=27328&pubmed-linkout=1
Oncotarget Han RH,et al

Nov 18th, 2019 - Metastases from melanoma, lung and breast cancer are among the most common causes of intracranial malignancy. Standard of care for brain metastases include a combination of surgical resection, stereotactic radiosurgery, and whole-brain radiation. ...

Tests for Melanoma Skin Care
https://www.cancer.org/cancer/melanoma-skin-cancer/detection-diagnosis-staging/how-diagnosed.html
American Cancer Society;

Aug 13th, 2019 - Most melanomas are brought to a doctor’s attention because of signs or symptoms a person is having. If you have an abnormal area on your skin that might be cancer, your doctor will examine it and might do tests to find out if it is melanoma, anoth...

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Drugs  59 results see all →

Clinicaltrials.gov  59,719 results

Reflectance confocal microscopy terminology glossary for melanocytic skin lesions: A sy...
https://doi.org/10.1016/j.jaad.2020.05.097
Journal of the American Academy of Dermatology; Navarrete-Dechent C, Liopyris K et. al.

May 26th, 2020 - There is lack of uniformity in the reflectance confocal microscopy (RCM) terminology for melanocytic lesions. To review published RCM terms for melanocytic lesions and identify redundant, synonymous terms. Systematic review of original research ar...

The EORTC-DeCOG nomogram adequately predicts outcomes of patients with sentinel node-po...
https://doi.org/10.1016/j.ejca.2020.04.022
European Journal of Cancer (Oxford, England : 1990); Verver D, Rekkas A et. al.

May 26th, 2020 - Based on recent advances in the management of patients with sentinel node (SN)-positive melanoma, we aimed to develop prediction models for recurrence, distant metastasis (DM) and overall mortality (OM). The derivation cohort consisted of 1080 pat...

In-depth plasma proteomics reveals increase in circulating PD-1 during anti-PD-1 immuno...
https://doi.org/10.1136/jitc-2019-000204
Journal for Immunotherapy of Cancer; Babačić H, Lehtiö J et. al.

May 26th, 2020 - Immune checkpoint inhibitors (ICIs) have significantly improved the outcome in metastatic cutaneous melanoma (CM). However, therapy response is limited to subgroups of patients and clinically useful predictive biomarkers are lacking. To discover t...

RHPN1-AS1 promotes cell proliferation and migration via miR-665/Akt3 in ovarian cancer.
https://doi.org/10.1038/s41417-020-0180-0
Cancer Gene Therapy; Zhao J, Yang T et. al.

May 26th, 2020 - Recent efforts have revealed that long non-coding RNAs exert crucial roles in cancer initiation and progression. RHPN1-AS1 is a 2030 bp transcript from human chromosome 8q24, and involved in tumorigenesis in uveal melanoma and non-small cell lung ...

The association between smoking and risk of skin cancer: a meta-analysis of cohort stud...
https://doi.org/10.1007/s10552-020-01319-8
Cancer Causes & Control : CCC; Arafa A, Mostafa A et. al.

May 26th, 2020 - The association between smoking and the risk of skin cancers has been studied without reaching consistent findings. This study aims to assess this association through an updated meta-analysis of cohort studies. We retrieved cohort studies that inv...

see more →

News  4,889 results

Trial of Intermittent Dabrafenib/Trametinib Dosing for BRAF-Mutated Melanoma Fails
https://www.medscape.com/viewarticle/930074

May 6th, 2020 - NEW YORK (Reuters Health) - A new study has dashed hopes that intermittent dosing of BRAF inhibitor dabrafenib and the MEK inhibitor trametinib would be as effective as continuous dosing of the drugs in patients with advanced BRAF-mutated melanoma...

RNA Biomarkers May Shed Light on Cancer Immunotherapy Response
https://www.medscape.com/viewarticle/929034

Apr 20th, 2020 - NEW YORK (Reuters Health) - Long noncoding RNAs (lncRNAs) tied to innate and adaptive immunity in cancer may provide an indication of response to immunotherapy, according to Chinese researchers. "This study is the first to identify lncRNA as a pro...

Encorafenib Now Approved for BRAF-Positive Colorectal Cancer
https://www.medscape.com/viewarticle/928414

Apr 8th, 2020 - The targeted agent encorafenib (Braftovi, Array BioPharma, now part of Pfizer) has been approved by the US Food and Drug Administration (FDA) for use in BRAF-positive colorectal cancer (CRC) and offers a subgroup of patients with CRC a chemotherap...

NCCN Panel: Defer Nonurgent Skin Cancer Care During Pandemic
https://www.medscape.com/viewarticle/928440

Apr 8th, 2020 - Amid the COVID-19 pandemic, defer therapeutic lymphadenectomy for stage III melanoma and opt instead for treatment with checkpoint or BRAF/MEK inhibitors, except when metastatic nodes are threatening vital structures or neoadjuvant therapy is not ...

Side Effects From Immune Checkpoint Inhibitors Vary by Regimen in Advanced Melanoma
https://www.medscape.com/viewarticle/928285

Apr 7th, 2020 - NEW YORK (Reuters Health) - Some immune-checkpoint inhibitor (ICI) regimens for advanced melanoma carry a lower risk of immune-related adverse events (irAEs) than others, according to a new systemic review and network meta-analysis. "These finding...

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Patient Education  99 results see all →