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About 95,140 results

ALLMedicine™ Melanoma Center

Research & Reviews  28,181 results

Dermoscopy, other modalities for improving melanoma diagnoses reviewed
https://www.mdedge.com/dermatology/article/261099/melanoma/dermoscopy-other-modalities-improving-melanoma-diagnoses
Doug Brunk

Feb 7th, 2023 - San Diego – Despite advances in dermoscopy and other techniques for diagnosing cutaneous melanoma, histology remains the gold standard. “I don’t think that’s going to change in the short term,” Travis W.

Neo-adjuvant immunotherapy emerges as best medical practice, and will be the new standa...
https://doi.org/10.1016/j.ejca.2023.01.004
European Journal of Cancer (Oxford, England : 1990); van Akkooi ACJ, Blank C et. al.

Feb 5th, 2023 - Survival of macroscopic stage III melanoma is poor. Five-year overall survival and relapse-free survival rates for surgery alone range from 40 to 59% and 30 to-39%, respectively. The current standard of care is therapeutic lymph node dissection (T...

Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-...
https://doi.org/10.1186/s12967-023-03906-0
Journal of Translational Medicine; Wang W, Tang X et. al.

Feb 5th, 2023 - Our previous study showed that fucosyltransferase 2 (Fut2) deficiency is closely related to colitis. Colitis increases the risk for the development of colorectal cancer (CRC). This study aimed to investigate the effect and underlying mechanism of ...

Enhanced brain entry of checkpoint-inhibitory therapeutic antibodies facilitated by int...
https://doi.org/10.3171/2022.12.JNS221285
Journal of Neurosurgery; Wang W, He H et. al.

Feb 5th, 2023 - Immune checkpoint-inhibitory therapeutic antibodies have shown striking activity against several types of cancers but are less effective against brain-localized malignancies, in part due to the protective effect of the blood-brain barrier (BBB). T...

Prognostic value of genetic aberrations and tumor immune microenvironment in primary ac...
https://doi.org/10.1186/s12967-022-03856-z
Journal of Translational Medicine; Huang R, Shen G et. al.

Feb 5th, 2023 - Acral melanoma (AM) is the most common subtype in Chinese melanoma patients with a very poor prognosis. However, our understanding of the disease pathogenesis and molecular landscape is limited by the few studies that have been conducted. Here, we...

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Guidelines  43 results

Fish intake and risk of melanoma in the NIH-AARP diet and health study
https://link.springer.com/article/10.1007/s10552-022-01588-5
Cancer Causes Control; Li, Y. et. al.

Jun 9th, 2022 - Prior epidemiological studies evaluating the association between fish intake and melanoma risk have been few and inconsistent. Few studies distinguished different types of fish intake with risk of melanoma.

Higher fish consumption associated with increased melanoma risk, study suggests
https://www.brown.edu/news/2022-06-09/fish-melanoma
News from Brown University;

Jun 9th, 2022 - A new analysis from a Brown University team shows a connection between eating fish and developing skin cancer, and the researchers say bio-contaminants like mercury are a likely cause.

European consensus-based interdisciplinary guideline for melanoma. Part 2: Treatment - ...
https://doi.org/10.1016/j.ejca.2022.04.018
European Journal of Cancer (Oxford, England : 1990); Garbe C, Amaral T et. al.

May 28th, 2022 - A unique collaboration of multidisciplinary experts from the European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO), and the European Organization of Research and Treatment of Cancer (EORTC) was formed to make recomm...

Clinical features, molecular characteristics and surgical management of primary penile ...
https://doi.org/10.1097/CMR.0000000000000788
Melanoma Research; Cakir OO, Pozzi E et. al.

Nov 30th, 2021 - Penile mucosal melanoma is an aggressive and rare genital malignancy. The aim of the present study was to review the management and outcomes of a homogenous cohort of patients with histologically confirmed penile mucosal melanoma, at a single spec...

New Eye Cancer Therapy Shown to Target Cancer Cells, Spare Vision
https://www.aao.org/newsroom/news-releases/detail/new-eye-cancer-therapy-shown-to-target-cancer-cell
American Academy of Ophthalmology

Nov 15th, 2021 - NEW ORLEANS, La. – Choroidal melanoma is a rare cancer that affects the back of the eye. If the tumor grows, it can cause the retina to detach, leading to vison loss. And if it spreads to other parts of the body, it can be fatal. There are no appr...

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Drugs  73 results see all →

Clinicaltrials.gov  3,022 results

The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)
https://clinicaltrials.gov/ct2/show/NCT04866810

Feb 3rd, 2023 - Background: The human gut microbiome is a topic of growing research interest because it modulates many systems, including immune function; and, alterations of the microbiome have been associated with the development of many diseases, including can...

Personalized Circulating DNA Follow-up in Melanoma (PERCIMEL)
https://clinicaltrials.gov/ct2/show/NCT04866680

Feb 3rd, 2023 - PERCIMEL is an open multicentric study. The purpose of this study is to assess the interest of molecular analysis on circulating tumor DNA in the follow-up of the disease.

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)
https://clinicaltrials.gov/ct2/show/NCT04044859

Feb 3rd, 2023 - Conditions: Endometrial Esophageal Cancer Esophagogastric Junction (EGJ) Gastric (stomach) Head and Neck Melanoma Non-small Cell Lung (NSCLC) Ovarian Cancer

Validating Pain Scales in Children and Young Adults
https://clinicaltrials.gov/ct2/show/NCT01639950

Feb 3rd, 2023 - Background: Pain is a common symptom among children with a variety of medical illnesses. Currently, a number of rating scales are used to assess pain interference and pain severity in adults. However, relatively few measures assessing these variab...

Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype
https://clinicaltrials.gov/ct2/show/NCT03718767

Feb 3rd, 2023 - BACKGROUND: Glioma is the most common malignant brain tumor. Genes coding for isocitrate dehydrogenases 1and 2 (IDH1 and IDH2), metabolic enzymes, are frequently mutated in gliomas, particularly lower-grade gliomas (LGGs). IDH1/2 mutation causes a...

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News  6,663 results

Dermoscopy, other modalities for improving melanoma diagnoses reviewed
https://www.mdedge.com/dermatology/article/261099/melanoma/dermoscopy-other-modalities-improving-melanoma-diagnoses
Doug Brunk

Feb 7th, 2023 - San Diego – Despite advances in dermoscopy and other techniques for diagnosing cutaneous melanoma, histology remains the gold standard. “I don’t think that’s going to change in the short term,” Travis W.

Dermatopathologist reflects on the early history of melanoma
https://www.mdedge.com/dermatology/article/260915/melanoma/dermatopathologist-reflects-early-history-melanoma
Doug Brunk

Jan 30th, 2023 - SAN DIEGO – Evidence of melanoma in the ancient past is rare, but according to James W. Patterson, MD, signs of melanoma with cutaneous lesions and diffuse bony metastases have been discovered in Peruvian Inca mummies.

How should PRAME be used to evaluate melanocytic lesions?
https://www.mdedge.com/dermatology/article/260874/melanoma/how-should-prame-be-used-evaluate-melanocytic-lesions
Doug Brunk

Jan 27th, 2023 - SAN DIEGO – As with many markers for the evaluation of challenging melanocytic lesions, preferentially expressed antigen in melanoma (PRAME) has its benefits and drawbacks, according to Cora Humberson, MD. “I’m a fan, but there are issues with it,.

MDM2 Inhibitor Breaks Through in Trial of Liposarcoma, Other Advanced Malignancies
https://www.medpagetoday.com/hematologyoncology/othercancers/102805

Jan 26th, 2023 - Almost half of patients with advanced solid tumors or lymphomas experienced disease control with a drug that reactivates the TP53 tumor suppressor, a first-in-human study showed. Overall, the oral murine double minute-2 (MDM2) inhibitor milademeta...

A toddler presents with a dark line on a fingernail
https://www.mdedge.com/pediatrics/article/260664/dermatology/toddler-presents-dark-line-fingernail
MDedge Pediatrics; Michael A. Haft, MD, Jennifer Y. Sui et. al.

Jan 18th, 2023 - Given the over 1-year history of an unchanging longitudinal band of pigment without extension to the proximal or lateral nailfolds or any other nail findings, the most likely diagnosis is benign longitudinal melanonychia. Longitudinal melanonychia.

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Patient Education  74 results see all →