ALLMedicine™ Melanoma Center
Research & Reviews 23,195 results
https://doi.org/10.1245/s10434-022-11869-7 10.1245/s10434-018-6513-7 10.1016/j.ejca.2019.10.027 10.1016/j.surg.2015.12.002 10.1002/bjs.11946 10.1002/bjs.10995 10.1200/JCO.2009.22.8239 10.1186/s12885-018-4016-3 10.1136/bmj.i6 10.1200/jco.2015.65.5654 10.1200/po.19.00206 10.1200/JCO.19.02362 10.2217/fon-2018-0912 10.1001/jamadermatol.2020.1729 10.1007/s11606-021-06737-1 10.1001/jamanetworkopen.2020.2401 10.1136/ebmed-2014-110140 10.1056/NEJM198005153022003 10.1245/s10434-016-5642-0 10.1056/NEJMoa060992 10.1016/j.ejca.2020.08.029 10.1001/jamadermatol.2020.1731 10.1056/NEJMoa1802357 10.1056/NEJMoa1709030 10.1056/NEJMoa2005493 10.1056/NEJMoa1708539
Annals of Surgical Oncology; Bartlett EK, Grossman D et. al.
May 19th, 2022 - Risk-based thresholds to guide management are undefined in the treatment of primary cutaneous melanoma but are essential to advance the field from traditional stage-based treatment to more individualized care. To estimate treatment risk thresholds...
https://doi.org/10.1007/s00394-022-02899-8 10.1093/jn/136.1.166 10.1080/01635581.2013.768348 10.1002/ijc.29569 10.1186/s13058-015-0521-3 10.3390/nu10020112 10.1158/1055-9965.EPI-15-0246 10.1002/cncr.24328 10.1093/ajcn/84.1.95 10.1097/FPC.0b013e3283498ecf 10.1093/carcin/bgi206 10.1002/ijc.23336 10.1093/jnci/87.3.190 10.1002/ijc.11034 10.1093/jnci/djh336 10.1016/j.jsbmb.2007.05.012 10.1186/bcr767 10.1001/jama.295.21.2492 10.1158/1055-9965.EPI-10-0188 10.1038/modpathol.3800255 10.1073/pnas.191367098 10.1093/jnci/djh025 10.1186/bcr2261 10.1016/j.cdp.2005.07.004 10.1158/1055-9965.EPI-06-0806 10.1186/s13058-015-0521-3 10.1158/1078-0432.CCR-14-1748 10.3945/ajcn.115.120147 10.1016/S1047-2797(98)00055-6 10.1093/jnci/djt043 10.1093/gerona/glw078 10.1053/j.ajkd.2013.03.013 10.1097/01.ASN.0000031805.09178.37 10.1016/S1047-2797(03)00043-7 10.1080/01621459.1999.10474144 10.1002/sim.7501 10.1177/0962280206074463 10.1002/9780470316696 10.1080/10408398.2016.1247252 10.1007/s00394-019-02018-0 10.1093/oxfordjournals.aje.a116870 10.1017/S1368980011000371 10.1001/archinte.168.18.2022 10.1038/bjc.1994.258 10.1007/s10552-009-9396-x 10.1002/ijc.23336 10.1016/j.ajog.2008.10.019 10.1016/j.ygyno.2013.03.014 10.1007/s10552-018-1028-x 10.3945/ajcn.111.022533 10.1172/JCI37385 10.1017/S002966511100320X 10.1016/j.numecd.2015.05.005 10.1002/ijc.22717 10.1093/ajcn/87.5.1384 10.1093/ajcn/75.3.492 10.1158/1055-9965.EPI-15-0187 10.1093/ajcn/69.2.243 10.1093/oxfordjournals.aje.a114086 10.1007/s10549-018-4667-4
European Journal of Nutrition; Yaghjyan L, McLaughlin E et. al.
May 19th, 2022 - We investigated the association of coffee and caffeine with breast cancer (BCa) risk, overall and by ER/PR status. We also examined potential interactions of coffee and caffeine with postmenopausal hormone use. Our study included 77,688 postmenopa...
https://doi.org/10.1158/0008-5472.CAN-21-4152
Cancer Research; Bonfill-Teixidor E, Iurlaro R et. al.
May 19th, 2022 - The therapeutic benefit of approved BRAF and MEK inhibitors (BRAFi/MEKi) in patients with brain metastatic BRAF V600E/K-mutated melanoma is limited and transient. Resistance largely occurs through the restoration of MAPK signaling via paradoxical ...
https://doi.org/10.1111/acel.13625
Aging Cell; Gupta P, Majumdar AG et. al.
May 19th, 2022 - Mutation in Werner (WRN) RECQL helicase is associated with premature aging syndrome (Werner syndrome, WS) and predisposition to multiple cancers. In patients with solid cancers, deficiency of the WRN RECQL helicase is paradoxically associated with...
https://doi.org/10.1080/21645515.2022.2030170
Human Vaccines & Immunotherapeutics; Rossi E
May 19th, 2022 - Editorial of special focus on melanoma immunotherapy.|2022|Rossi E,|
Guidelines 38 results
https://doi.org/10.1097/CMR.0000000000000788
Melanoma Research; Cakir OO, Pozzi E et. al.
Nov 30th, 2021 - Penile mucosal melanoma is an aggressive and rare genital malignancy. The aim of the present study was to review the management and outcomes of a homogenous cohort of patients with histologically confirmed penile mucosal melanoma, at a single spec...
https://www.aao.org/newsroom/news-releases/detail/new-eye-cancer-therapy-shown-to-target-cancer-cell
American Academy of Ophthalmology
Nov 15th, 2021 - NEW ORLEANS, La. – Choroidal melanoma is a rare cancer that affects the back of the eye. If the tumor grows, it can cause the retina to detach, leading to vison loss. And if it spreads to other parts of the body, it can be fatal. There are no appr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482100
Current Oncology (Toronto, Ont.); Thawer A, Miller WH et. al.
Oct 1st, 2021 - The combination of dabrafenib and trametinib is a well-established treatment for BRAF-mutated melanoma. However, the effectiveness of this approach may be hindered by the development of treatment-related pyrexia syndrome, which occurs in at least ...
http://pressroom.cancer.org/ARN2021
American Cancer Society
Jul 8th, 2021 - Overall cancer death rates continue to decline in men and women for all racial and ethnic groups in the United States, according to the latest Annual Report to the Nation on the Status of Cancer. During 2001 to 2018, declines in lung cancer death ...
https://doi.org/10.6004/jnccn.2021.0018
Journal of the National Comprehensive Cancer Network : JN... Swetter SM, Thompson JA et. al.
Apr 13th, 2021 - Over the past few years, the NCCN Guidelines for Melanoma: Cutaneous have been expanded to include pathways for treatment of microscopic satellitosis (added in v2.2020), and the following Principles sections: Molecular Testing (added in v2.2019), ...
Drugs 50 results see all →
Clinicaltrials.gov 1,007 results
https://clinicaltrials.gov/ct2/show/NCT03739827
May 13th, 2022 - Background: Rare tumors are defined as fewer than 150 incident cases per one million per year. Consequently, only 11 tumor types are common in U.S. adults (prostate, breast, lung/bronchus, colon, uterus, bladder, melanoma, rectum, ovary, non-Hodgk...
https://clinicaltrials.gov/ct2/show/NCT01174121
May 13th, 2022 - Background: Metastatic digestive tract cancers, in particular esophageal, gastric, pancreatic and hepatobiliary carcinomas, are associated with poor survival beyond five years and poor response to existing therapies. Data from the National Cancer ...
https://clinicaltrials.gov/ct2/show/NCT00297895
May 13th, 2022 - Subjects must be diagnosed with melanoma. All subjects receive sentinel lymphadenectomy. If the subject is sentinel node positive and meets study requirements, the subject is randomized to receive either (1) completion lymphadenectomy (2) observat...
https://clinicaltrials.gov/ct2/show/NCT04566133
May 13th, 2022 - Background: Among the new cases of bile tract carcinoma (BTC) that are diagnosed every year in the United States, there are approximately 6,500 cases of gallbladder carcinoma, 3,000 cases of extrahepatic cholangiocarcinoma, and 3,000 cases of intr...
https://clinicaltrials.gov/ct2/show/NCT01639950
May 13th, 2022 - Background: Pain is a common symptom among children with a variety of medical illnesses. Currently, a number of rating scales are used to assess pain interference and pain severity in adults. However, relatively few measures assessing these variab...
News 3,500 results
https://www.medscape.com/viewarticle/973804
May 11th, 2022 - A mutation in a gene involved in chromatin remodeling is associated with aggressive melanoma, according to a new study that combined in vitro and animal model data. The gene, ARID2, is a part of the switch/sucrose nonfermentable (SWI/SNF) complex,...
https://www.medscape.com/viewarticle/973618
May 9th, 2022 - Patients with thyroid cancer may experience greater financial challenges compared to those with other common cancers, a recent review suggests. Researchers found, for instance, that patients with thyroid cancer had higher total yearly healthcare e...
https://www.onclive.com/view/nivolumab-plus-pd-l1-ido-peptide-vaccine-displays-impressive-efficacy-in-metastatic-melanoma
May 5th, 2022 - Nivolumab (Opdivo) in combination with a PD-L1/IDO peptide vaccine displayed encouraging efficacy and survival results among patients with metastatic melanoma, according to data from a phase 1/2 trial (NCT03047928) presented at the 2022 AACR Annua...
https://www.onclive.com/view/sot101-plus-pembrolizumab-elicits-encouraging-efficacy-in-advanced-solid-tumors
May 2nd, 2022 - The addition of SOT101, an interleukin (IL)-2/IL-15 Rβγ superagonist, to Pembrolizumab (Keytruda) generated a clinical benefit and encouraging safety data in patients with advanced solid tumors, according to data presented at the 2022 AACR Annual ...
https://www.onclive.com/view/sotigalimab-plus-pembrolizumab-elicits-broad-immune-activity-in-metastatic-melanoma
May 2nd, 2022 - The combination of the CD40 agonist antibody sotigalimab (APX005M) and pembrolizumab (Keytruda) demonstrated a favorable safety profile and led to immunologic changes that correlated with clinical response in patients with unresectable stage III o...