About 960 results

ALLMedicine™ Paronychia Center

Research & Reviews  278 results

FDA Approval Summary: Mobocertinib for Metastatic Non-Small Cell Lung Cancer with EGFR ...
Clinical Cancer Research : an Official Journal of the Ame... Duke ES, Stapleford L et. al.

Sep 17th, 2022 - On September 15, 2021, the U.S. Food and Drug Administration (FDA) granted accelerated approval to mobocertinib (Exkivity, Takeda Pharmaceuticals USA, Inc.) for the treatment of adult patients with locally advanced or metastatic non-small cell lun...

Reaffirming Adverse Events Related to Lung Cancer Survivors' Target Therapies and Their...
Cancer Nursing; Yu CC, Chu CY et. al.

Sep 13th, 2022 - Most advanced non-small-cell lung cancer (NSCLC) patients received targeted therapies of epidermal growth factor receptor tyrosine kinase inhibitors. However, few studies reported the relationships between adverse events (AEs) and psychological di...

Optimizing Antibiotic Treatment of Skin Infections in Pediatric Emergency and Urgent Ca...
Pediatrics Wiltrakis SM, Jaggi P et. al.

Sep 9th, 2022 - The objective was to optimize antibiotic choice and duration for uncomplicated skin/soft tissue infections (SSTIs) discharged from pediatric emergency departments (EDs) and urgent cares (UCs). Pediatric patients aged 0 to 18 years discharged from ...

Association between dermatologic adverse events and quality of life in lung cancer pati...
Supportive Care in Cancer : Official Journal of the Multi... Hsu HT, Yu CC et. al.

Sep 4th, 2022 - Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are frequently associated with dermatologic adverse events (dAEs), having great impacts on patients' health-related quality of life (HRQoL) and treatment adherence. We aimed t...

Acute paronychia in a neonate secondary to clindamycin-resistant Staphylococcus aureus.
Pediatric Dermatology; Osmani S, Schairer DO

Sep 2nd, 2022 - Paronychia is a common inflammatory condition of the nail fold that is often associated with infection. Causes can be fungal, viral, or most commonly, bacterial. Neonatal paronychia is a rare presentation with only one previously reported case in ...

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Guidelines  1 results

Expert Consensus on the Management of Adverse Events from EGFR Tyrosine Kinase Inhibito...
Drugs Califano R, Tariq N et. al.

Jul 19th, 2015 - Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) such as gefitinib, erlotinib, and afatinib are standard-of-care for first-line treatment of EGFR-mutant advanced non-small cell lung cancer (NSCLC). These drugs have a prove...

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Drugs  1 results see all →

Clinicaltrials.gov  12 results

Effect of Zanthoxylum Nitidum Tincture for Paronychia Caused by Afatinib

Aug 15th, 2022 - This is a randomized control trial evaluating the efficacy of zanthoxylum nitidum tincture on preventing progression of paronychia caused by afatinib from grade 1 to grade 2/3. Enrolled participates will randomly receive original treatment or orig...

The Efficacy of Topical Timolol Combined With Cryotherapy in EGFR Inhibitors-induced Paronychia - a Double-blinded, Intrapatient Left-to-right Controlled Study

Jun 8th, 2022 - Background: EGFR inhibitors (EGFRi) have been used to treat a wide variety of cancers nowadays. One of the major side effects of EGFRi is paronychia, which was not fatal but may caused huge negative impact on patient's daily activities. Current gu...

Panitumumab Skin Toxicity Prevention Trial

Sep 9th, 2021 - Background and rationale: EGFR represents the main and more studied signal activation pathway in the development of colorectal carcinoma. KRAS, NRAS, BRAF and PI3KA mutations and ERBB2 and MET amplification are responsible for most of the cases of...

StrataCTX® as a Steroid Sparing Device

Aug 9th, 2021 - Topical steroids are the mainstays of treatment for many cutaneous reactions and disorders. Steroids are known to cause many side effects and few effective pharmacologic alternatives exist. Contact dermatitis is observed in 56% of patients with cu...

Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitor...

Jul 9th, 2021 - The arrival of new therapeutic strategies such as targeted therapies has led to real progress in the treatment of cancers. Tyrosine kinase inhibitors and antibodies to epidermal growth factor receptors (EGFR), or iEGFR, target one of the major pat...

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News  91 results

Nail Salon Safety: From Nail Dystrophy to Acrylate Contact Allergies
Sonali Nanda, MD

Aug 4th, 2022 - As residents, it is important to understand the steps of the manicuring process and be able to inform patients on how to maintain optimal nail health while continuing to go to nail salons. Most patients are not aware of the possible allergic, trau.

Rippled Macules and Papules on the Legs
Kieu Oanh Nguyen, MD, Kristopher M. Peters, DO

Jun 7th, 2022 - The Diagnosis: Cutaneous Amyloidosis A punch biopsy confirmed the diagnosis of cutaneous amyloidosis, which is characterized by the deposition of amyloid proteins in the skin without systemic involvement. Subtypes of cutaneous amyloidosis include.

Management of Pediatric Nail Psoriasis
Kerasia-Maria Plachouri, MD, PhD, Francesk Mulita, MD, PhD et. al.

Nov 4th, 2021 - Pediatric nail psoriasis is a condition that has not been extensively studied. The prevalence of nail alterations in pediatric patients with psoriasis varies among different studies, ranging from 17% to 39.

NSCLC: Mobocertinib for Patients With EGFR Exon 20 Insertion Mutations

Oct 27th, 2021 - Transcript: Erminia Massarelli, MD, MS, PhD: The mechanism of action of mobocertinib [Exkivity] is an irreversible EGFR tyrosine kinase inhibitor. However, it differs from osimertinib [Tagrisso], which is currently approved for exon 19 and21 muta...

Painful Psoriasiform Plaques
Maria Amoreth R. Gozo, MD, Iviensan F. Manalo, MD et. al.

Oct 7th, 2021 - The Diagnosis: Acquired Acrodermatitis Enteropathica A punch biopsy of an elevated scaly border of the rash on the thigh revealed parakeratosis, absence of the granular layer, and epidermal pallor with psoriasiform and spongiotic dermatitis (Figur.

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Patient Education  1 results see all →