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About 2,655 results

ALLMedicine™ Hyperkeratosis Center

Research & Reviews  1,255 results

Japanese guidelines for the management of palmoplantar keratoderma.
https://doi.org/10.1111/1346-8138.15850
The Journal of Dermatology; Yoneda K, Kubo A et. al.

Jun 14th, 2021 - Palmoplantar keratoderma (PPK) is a collective term for keratinizing disorders in which the main clinical symptom is hyperkeratosis on the palms and soles. To establish the first Japanese guidelines approved by the Japanese Dermatological Associat...

Gingival Leukoplakia: Hyperkeratosis with Epithelial Atrophy Is A Frequent Histopatholo...
https://doi.org/10.1007/s12105-021-01333-5 10.1016/j.jaad.2007.07.011 10.1007/s12105-020-01151-1 10.1007/s12105-019-01020-6 10.1016/j.oooo.2013.09.017 10.1111/odi.12095 10.4317/medoral.22326 10.1007/s12105-020-01216-1 10.1016/j.oooo.2014.09.016 10.1186/1472-6831-14-99 10.1016/j.bjoms.2015.08.268 10.1111/jop.12899 10.1371/journal.pone.0225682 10.1093/jnci/djz238 10.1007/s00784-020-03322-4 10.1016/j.oraloncology.2018.10.021 10.1016/j.oraloncology.2005.08.011 10.1016/j.jcms.2015.03.011 10.1111/j.1600-0714.2012.01167.x 10.1016/j.oooo.2018.02.012 10.1111/bjd.12853 10.1016/S1079-2104(97)90062-7 10.1034/j.1600-0714.2003.00167.x 10.14219/jada.archive.2007.0236 10.1007/s12105-018-0986-3 10.1111/j.1600-0714.2009.00790.x 10.1007/s12105-020-01262-9 10.1111/j.1600-0714.2007.00582.x 10.1111/jop.12726 10.1007/s12105-018-0893-7 10.1038/modpathol.2016.121 10.1016/j.oooo.2013.12.413 10.1007/s12105-019-01006-4 10.1038/nri3384 10.1053/j.seminoncol.2015.05.003 10.1097/01.pas.0000149687.90710.21 10.1038/s41598-020-63148-8 10.1056/NEJMoa1503093 10.1056/NEJMoa1606774 10.1016/s0140-6736(19)32591-7 10.1016/j.cell.2011.02.013 10.4317/jced.57091 10.1177/2057178x16654704 10.1016/j.oooo.2017.12.011 10.1111/j.1600-0714.2006.00491.x 10.1111/odi.13155 10.1038/nature14129 10.1111/odi.13156 10.1158/1940-6207.CAPR-13-0001 10.1111/odi.13797 10.1056/NEJMp1508811
Head and Neck Pathology; Alabdulaaly L, Almazyad A et. al.

May 31st, 2021 - White lesions on the gingiva and palatal mucosa may represent reactive keratoses, including specific diseases such as benign alveolar ridge keratosis, or nonreactive keratoses, such as true leukoplakia, the latter being associated with a high recu...

Ichthyosis: case report in a Colombian man with genetic alterations in ABCA12 and HRNR ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157432
BMC Medical Genomics; Arias-Pérez RD, Gallego-Quintero S et. al.

May 27th, 2021 - Ichthyosis is a heterogeneous group of diseases caused by genetic disorders related to skin formation. They are characterized by generalized dry skin, scaling, hyperkeratosis and frequently associated with erythroderma. Among its different types, ...

Basaloid follicular hamartomas in pediatric Basal Cell Nevus Syndrome: A diagnostic cha...
https://doi.org/10.1111/1346-8138.15892
The Journal of Dermatology; Besagni F, Dika E et. al.

May 22nd, 2021 - Basal Cell Nevus Syndrome (BCNS) is an autosomal dominant inherited disease caused by PTCH1 (9q22.3-q31) germline mutations. Skin manifestations are mainly characterized by hyperkeratosis of the palms and soles, palmoplantar pits and a strong pred...

Costello syndrome with special cutaneous manifestations and HRAS G12D mutation: A case ...
https://doi.org/10.1002/mgg3.1690
Molecular Genetics & Genomic Medicine; Qian W, Zhang M et. al.

May 1st, 2021 - Costello syndrome (CS, OMIM 218040) is a rare congenital disorder caused by mutations in HRAS. Previous studies reported that approximately 80% of patients with CS share the same pathogenic variant in HRAS gene in c.34G> A (p.G12S). Here, we repor...

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Clinicaltrials.gov  1,285 results

Japanese guidelines for the management of palmoplantar keratoderma.
https://doi.org/10.1111/1346-8138.15850
The Journal of Dermatology; Yoneda K, Kubo A et. al.

Jun 14th, 2021 - Palmoplantar keratoderma (PPK) is a collective term for keratinizing disorders in which the main clinical symptom is hyperkeratosis on the palms and soles. To establish the first Japanese guidelines approved by the Japanese Dermatological Associat...

Gingival Leukoplakia: Hyperkeratosis with Epithelial Atrophy Is A Frequent Histopatholo...
https://doi.org/10.1007/s12105-021-01333-5 10.1016/j.jaad.2007.07.011 10.1007/s12105-020-01151-1 10.1007/s12105-019-01020-6 10.1016/j.oooo.2013.09.017 10.1111/odi.12095 10.4317/medoral.22326 10.1007/s12105-020-01216-1 10.1016/j.oooo.2014.09.016 10.1186/1472-6831-14-99 10.1016/j.bjoms.2015.08.268 10.1111/jop.12899 10.1371/journal.pone.0225682 10.1093/jnci/djz238 10.1007/s00784-020-03322-4 10.1016/j.oraloncology.2018.10.021 10.1016/j.oraloncology.2005.08.011 10.1016/j.jcms.2015.03.011 10.1111/j.1600-0714.2012.01167.x 10.1016/j.oooo.2018.02.012 10.1111/bjd.12853 10.1016/S1079-2104(97)90062-7 10.1034/j.1600-0714.2003.00167.x 10.14219/jada.archive.2007.0236 10.1007/s12105-018-0986-3 10.1111/j.1600-0714.2009.00790.x 10.1007/s12105-020-01262-9 10.1111/j.1600-0714.2007.00582.x 10.1111/jop.12726 10.1007/s12105-018-0893-7 10.1038/modpathol.2016.121 10.1016/j.oooo.2013.12.413 10.1007/s12105-019-01006-4 10.1038/nri3384 10.1053/j.seminoncol.2015.05.003 10.1097/01.pas.0000149687.90710.21 10.1038/s41598-020-63148-8 10.1056/NEJMoa1503093 10.1056/NEJMoa1606774 10.1016/s0140-6736(19)32591-7 10.1016/j.cell.2011.02.013 10.4317/jced.57091 10.1177/2057178x16654704 10.1016/j.oooo.2017.12.011 10.1111/j.1600-0714.2006.00491.x 10.1111/odi.13155 10.1038/nature14129 10.1111/odi.13156 10.1158/1940-6207.CAPR-13-0001 10.1111/odi.13797 10.1056/NEJMp1508811
Head and Neck Pathology; Alabdulaaly L, Almazyad A et. al.

May 31st, 2021 - White lesions on the gingiva and palatal mucosa may represent reactive keratoses, including specific diseases such as benign alveolar ridge keratosis, or nonreactive keratoses, such as true leukoplakia, the latter being associated with a high recu...

Ichthyosis: case report in a Colombian man with genetic alterations in ABCA12 and HRNR ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157432
BMC Medical Genomics; Arias-Pérez RD, Gallego-Quintero S et. al.

May 27th, 2021 - Ichthyosis is a heterogeneous group of diseases caused by genetic disorders related to skin formation. They are characterized by generalized dry skin, scaling, hyperkeratosis and frequently associated with erythroderma. Among its different types, ...

Basaloid follicular hamartomas in pediatric Basal Cell Nevus Syndrome: A diagnostic cha...
https://doi.org/10.1111/1346-8138.15892
The Journal of Dermatology; Besagni F, Dika E et. al.

May 22nd, 2021 - Basal Cell Nevus Syndrome (BCNS) is an autosomal dominant inherited disease caused by PTCH1 (9q22.3-q31) germline mutations. Skin manifestations are mainly characterized by hyperkeratosis of the palms and soles, palmoplantar pits and a strong pred...

Costello syndrome with special cutaneous manifestations and HRAS G12D mutation: A case ...
https://doi.org/10.1002/mgg3.1690
Molecular Genetics & Genomic Medicine; Qian W, Zhang M et. al.

May 1st, 2021 - Costello syndrome (CS, OMIM 218040) is a rare congenital disorder caused by mutations in HRAS. Previous studies reported that approximately 80% of patients with CS share the same pathogenic variant in HRAS gene in c.34G> A (p.G12S). Here, we repor...

see more →

News  115 results

Spiky Papules on the Dorsal Feet
https://www.mdedge.com/dermatology/article/218377/dermatopathology/spiky-papules-dorsal-feet?channel=204
Dema T. Alniemi, MD, Laura Greene, MD et. al.

Mar 4th, 2020 - The Diagnosis: Hyperkeratosis Lenticularis Perstans (Flegel Disease) Hyperkeratosis lenticularis perstans, also known as Flegel disease, is a rare dermatosis first described by Flegel1 in 1958. This benign disorder is characterized by multiple asy.

Target plantar keratoderma when managing ‘mild’ EBS
https://www.mdedge.com/dermatology/article/217704/medical-dermatology/target-plantar-keratoderma-when-managing-mild-ebs/page/0/2?channel=39212

Feb 23rd, 2020 - Although the jury is still out on the benefit of rocker bottom footwear, one thing that might help those with EBS who develop regular foot blisters may be to keep their weight in check. In a separate poster presentation given by Lynn Hubbard, a sp.

An 8-year-old girl presents with nail dystrophy, nail plate thinning
https://www.mdedge.com/pediatrics/article/217568/dermatology/8-year-old-girl-presents-nail-dystrophy-nail-plate-thinning?channel=41022
Catalina Matiz, MD

Feb 20th, 2020 - At a follow-up visit, a biopsy of the skin on the fingertips was performed, which showed lichenoid lymphocytic inflammatory infiltrate with associated hyperkeratosis, hypergranulosis, and acanthosis. No fungal elements were seen.

Nail dystrophy and nail plate thinning
https://www.mdedge.com/pediatrics/article/217568/dermatology/nail-dystrophy-and-nail-plate-thinning?channel=41022
Catalina Matiz, MD

Feb 20th, 2020 - At a follow-up visit, a biopsy of the skin on the fingertips was performed, which showed lichenoid lymphocytic inflammatory infiltrate with associated hyperkeratosis, hypergranulosis, and acanthosis. No fungal elements were seen.

Postinflammatory Hyperpigmentation Following Treatment of Hyperkeratosis Lenticularis Perstans With Tazarotene Cream 0.1%
https://www.mdedge.com/dermatology/article/207756/pigmentation-disorders/postinflammatory-hyperpigmentation-following?channel=44
Kristyna Gleghorn, MD, Tanya Riddle, MD et. al.

Sep 9th, 2019 - To the Editor: Hyperkeratosis lenticularis perstans (HLP), or Flegel disease, is a rare keratinization disorder characterized by asymptomatic, red-brown, 1- to 5-mm papules with irregular horny scales commonly seen on the dorsal feet and lower leg.

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