ALLMedicine™ Xeroderma Pigmentosum Center
Research & Reviews 400 results
https://clinicaltrials.gov/ct2/show/NCT00046189
May 20th, 2022 - Xeroderma Pigmentosum (XP) is a rare, recessive disorder with a more than 1000-fold increase in the frequency of all major skin cancers in association with defective DNA repair. The risk of skin and other cancers among normal appearing XP heterozy...
https://clinicaltrials.gov/ct2/show/NCT00001813
May 20th, 2022 - Three rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD) have defective DNA excision repair although only XP has increased cancer susceptibility. We plan to perform careful clinical examination...
https://doi.org/10.1016/j.jaad.2022.03.023
Journal of the American Academy of Dermatology; Krakowski AC, Hafeez F et. al.
May 17th, 2022 - Basal cell carcinoma (BCC) is the most common human cancer, with approximately 3.6 million cases diagnosed each year. About 2000 deaths annually in the United States are attributed to basal and squamous cell skin cancers. There is a direct link be...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9096195
Cell Transplantation; Dai W, Wu A et. al.
May 11th, 2022 - Glioblastoma is the most frequent, as well as aggressive kind of high-grade malignant glioma. Chemoresistance is posing a significant clinical barrier to the efficacy of temozolomide-based glioblastoma treatment. By suppressing xeroderma pigmentos...
https://doi.org/10.1177/11206721221100903
European Journal of Ophthalmology; Rajagopal R, Srinivasan B et. al.
May 11th, 2022 - To report a rare presentation of bilateral, coexisting ocular surface disease in a case of Xeroderma pigmentosum and its successful management. Case report. A 21-year-old male with Xeroderma pigmentosum presented with bilateral ocular surface squa...
Drugs 1 results see all →
Clinicaltrials.gov 8 results
https://clinicaltrials.gov/ct2/show/NCT00046189
May 20th, 2022 - Xeroderma Pigmentosum (XP) is a rare, recessive disorder with a more than 1000-fold increase in the frequency of all major skin cancers in association with defective DNA repair. The risk of skin and other cancers among normal appearing XP heterozy...
https://clinicaltrials.gov/ct2/show/NCT00001813
May 20th, 2022 - Three rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD) have defective DNA excision repair although only XP has increased cancer susceptibility. We plan to perform careful clinical examination...
https://clinicaltrials.gov/ct2/show/NCT05370235
May 11th, 2022 - The CUV152 study will evaluate the safety of afamelanotide in XP-C and XP-V patients, as well as the drug's ability to assist reparative processes following ultraviolet (UV) provoked DNA damage of the skin. It will assess whether SCENESSE® increas...
https://clinicaltrials.gov/ct2/show/NCT05159752
Jan 11th, 2022 - The CUV156 study will evaluate the safety of afamelanotide in XP-C patients, as well as the drug's ability to assist reparative processes following ultraviolet (UV) provoked DNA damage of the skin. It will assess whether SCENESSE® increases the am...
https://clinicaltrials.gov/ct2/show/NCT03445052
Jul 22nd, 2020 - Xeroderma Pigmentosum (XP) is a rare autosomal recessive inherited condition caused by defective Nucleotide Excision Repair. Patients may develop skin cancers from childhood onwards, ocular damage, and neurological deterioration. The clinical mana...
News 12 results
https://reference.medscape.com/viewarticle/936083_2
Aug 21st, 2020 - Primary risk factors and clinical warning signs for melanoma include: Changing mole (most important clinical warning sign) Presence of xeroderma pigmentosum or familial atypical mole melanoma syndrome Clinical atypical/dysplastic nevi in familial ...
https://www.medscape.com/viewarticle/923186
Dec 28th, 2019 - Simon Stevens, head of NHS England becomes a Sir, leading this year's healthcare field in the 2020 New Year Honours List. The recipients in healthcare are alongside stars of sport, entertainment, public service, politics, charity work, and "the ou...
https://www.mdedge.com/pediatrics/article/207921/pediatrics/expert-spotlights-telltale-clinical-signs-xeroderma-pigmentosum?channel=39313
Doug Brunk
Sep 10th, 2019 - AUSTIN, TEX. – If a child presents with acute photosensitivity at a young age, onset of freckling before the age of 2 years, and severe sun damage of the lips and eyes, think xeroderma pigmentosum (XP), a rare autosomal recessive disorder.
https://www.mdedge.com/dermatology/article/207921/pediatrics/expert-spotlights-telltale-clinical-signs-xeroderma
Doug Brunk
Sep 10th, 2019 - AUSTIN, TEX. – If a child presents with acute photosensitivity at a young age, onset of freckling before the age of 2 years, and severe sun damage of the lips and eyes, think xeroderma pigmentosum (XP), a rare autosomal recessive disorder.
https://www.mdedge.com/clinicianreviews/article/150902/rare-diseases/small-kansas-town-turns-night-day-boy-rare-disease
Nov 1st, 2017 - A new documentary video developed by NORD shows how a small community in Kansas came together to support an 11-year-old boy who has a rare disease that makes it necessary for him to avoid sunlight. Peyton Madden has xeroderma pigmentosum (XP), a r.