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About 3,606 results

ALLMedicine Kaposi Sarcoma Center

Research & Reviews  1,691 results

Immunoglobulin E (IgE) Levels are associated with Kaposi's Sarcoma in HIV-Infected Afri...
https://doi.org/10.1093/infdis/jiaa340
The Journal of Infectious Diseases; Byakwaga H, Barbachano-Guerrero A et. al.

Jun 18th, 2020 - Recently we demonstrated that activated mast cells (MCs) are enriched in Kaposi sarcoma (KS) tumors and contribute to the inflammatory microenvironment. Mechanisms driving MC activation, however, are incompletely understood. We sought to understan...

Oncogenic herpesvirus engages endothelial transcription factors SOX18 and PROX1 to incr...
https://doi.org/10.1158/0008-5472.CAN-19-3103
Cancer Research; Gramolelli S, Elbasani E et. al.

Jun 8th, 2020 - Kaposi sarcoma (KS) is a tumor caused by KS herpesvirus (KSHV) infection and is thought to originate from lymphatic endothelial cells (LEC). While KSHV establishes latency in virtually all susceptible cell types, LEC support spontaneous expression...

The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Pr...
https://doi.org/10.1158/0008-5472.CAN-19-3105
Cancer Research; Choi D, Park E et. al.

Jun 8th, 2020 - Kaposi's sarcoma (KS) is the most common cancer in HIV-positive individuals and is caused by KS-associated herpesvirus (KSHV). It is believed that a small number of latently infected KS tumor cells undergo spontaneous lytic reactivation to produce...

Tonsillar Kaposi sarcoma in a renal transplant patient.
https://doi.org/10.1111/tid.13347
Transplant Infectious Disease : an Official Journal of the Transplantation Society REFERENCES; Howard JH, Darrow M et. al.

Jun 4th, 2020 - Kaposi sarcoma (KS) is a vascular neoplasm caused by human herpesvirus-8 (HHV-8) infection. KS is most often seen in individuals with acquired immunodeficiency syndrome but can occur in patients who are on immunosuppressive therapy. While the skin...

Recommendations for treating life-threatening Kaposi sarcoma during pregnancy in HIV-po...
https://doi.org/10.1177/0956462420920160
International Journal of STD & AIDS; Bacha JM, El-Mallawany NK et. al.

Jun 2nd, 2020 - In areas of high HIV and human herpes virus 8 prevalence, life-threatening forms of Kaposi sarcoma (KS) can occur in HIV-positive women during pregnancy. Treating KS in pregnancy must balance both the well-being of the mother with the health of th...

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Guidelines  1 results

AIDS-Related Kaposi Sarcoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology
http://www.jnccn.org/content/17/2/171.full
Reid. E.,et al

Jan 31st, 2019 - As treatment of HIV has improved, people living with HIV (PLWH) have experienced a decreased risk of AIDS and AIDS-defining cancers (non-Hodgkin's lymphoma, Kaposi sarcoma, and cervical cancer), but the risk of Kaposi sarcoma in PLWH is still elev...

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Drugs  2 results see all →

Clinicaltrials.gov  1,787 results

Pomalidomide for Treatment of Kaposi Sarcoma
https://ascopost.com/issues/june-25-2020/pomalidomide-for-treatment-of-kaposi-sarcoma/

Jun 24th, 2020 - On May 14, 2020, pomalidomide was granted accelerated approval to treat adult patients with AIDS-related Kaposi sarcoma after failure of highly active antiretroviral therapy and for Kaposi sarcoma in adult patients who are HIV-negative.1,2 Pomalid...

Immunoglobulin E (IgE) Levels are associated with Kaposi's Sarcoma in HIV-Infected Afri...
https://doi.org/10.1093/infdis/jiaa340
The Journal of Infectious Diseases; Byakwaga H, Barbachano-Guerrero A et. al.

Jun 18th, 2020 - Recently we demonstrated that activated mast cells (MCs) are enriched in Kaposi sarcoma (KS) tumors and contribute to the inflammatory microenvironment. Mechanisms driving MC activation, however, are incompletely understood. We sought to understan...

Oncogenic herpesvirus engages endothelial transcription factors SOX18 and PROX1 to incr...
https://doi.org/10.1158/0008-5472.CAN-19-3103
Cancer Research; Gramolelli S, Elbasani E et. al.

Jun 8th, 2020 - Kaposi sarcoma (KS) is a tumor caused by KS herpesvirus (KSHV) infection and is thought to originate from lymphatic endothelial cells (LEC). While KSHV establishes latency in virtually all susceptible cell types, LEC support spontaneous expression...

The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Pr...
https://doi.org/10.1158/0008-5472.CAN-19-3105
Cancer Research; Choi D, Park E et. al.

Jun 8th, 2020 - Kaposi's sarcoma (KS) is the most common cancer in HIV-positive individuals and is caused by KS-associated herpesvirus (KSHV). It is believed that a small number of latently infected KS tumor cells undergo spontaneous lytic reactivation to produce...

Tonsillar Kaposi sarcoma in a renal transplant patient.
https://doi.org/10.1111/tid.13347
Transplant Infectious Disease : an Official Journal of the Transplantation Society REFERENCES; Howard JH, Darrow M et. al.

Jun 4th, 2020 - Kaposi sarcoma (KS) is a vascular neoplasm caused by human herpesvirus-8 (HHV-8) infection. KS is most often seen in individuals with acquired immunodeficiency syndrome but can occur in patients who are on immunosuppressive therapy. While the skin...

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News  123 results

FDA Approves Pomalidomide for Kaposi Sarcoma
https://www.medscape.com/viewarticle/930591

May 14th, 2020 - The US Food and Drug Administration (FDA) has granted accelerated approval to pomalidomide (Pomalyst, Bristol-Myers Squibb) for the treatment of AIDS-related Kaposi sarcoma that is resistant to highly active antiretroviral therapy (HAART) or that ...

Not So Classic, Classic Kaposi Sarcoma
https://www.mdedge.com/dermatology/article/217742/infectious-diseases/not-so-classic-classic-kaposi-sarcoma?channel=44
Maggie L. Chow, MD, PhD, Ashley J. Crew, MD et. al.

Feb 24th, 2020 - To the Editor: Kaposi sarcoma (KS) is a lymphatic endothelial cell neoplasm that frequently presents as multiple vascular cutaneous and mucosal nodules. 1 The classic KS variant typically is described as the presentation of KS in otherwise healthy.

Kaposi Sarcoma in a Patient With Postpolio Syndrome
https://www.mdedge.com/dermatology/article/213042/infectious-diseases/kaposi-sarcoma-patient-postpolio-syndrome?channel=44
Melodi Javid Whitley, MD, PhD, Willis Barrow, MD et. al.

Nov 25th, 2019 - Kaposi sarcoma (KS) is a low-grade vascular tumor that is rare among the general US population, with an incidence rate of less than 1 per 100,000. 1 The tumor is more common among certain groups of individuals due to geographic differences in the p.

Pulmonary Hemorrhage as the Initial Presentation of AIDS-Related Kaposi Sarcoma
https://www.mdedge.com/dermatology/article/210600/infectious-diseases/pulmonary-hemorrhage-initial-presentation-aids/page/0/1?channel=44

Oct 22nd, 2019 - Histologic examination of biopsies of the penile lesions revealed spindle cell proliferation with hemorrhage (Figure 2A) that stained positively for HHV-8 (Figure 2B), consistent with KS. Biopsies taken during bronchoscopy similarly revealed spind.

Violaceous papules on calf & foot
https://www.mdedge.com/dermatology/article/210336/medical-dermatology/violaceous-papules-calf-foot?channel=39212
Donna Bilu Martin, MD

Oct 17th, 2019 - Acroangiodermatitis of Mali, also called pseudo–Kaposi sarcoma, is an uncommon, benign condition that usually presents on the distal lower extremities or feet as red to violaceous papules, patches, and plaques. Clinically, lesions may look similar.

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Patient Education  2 results see all →