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About 2,110 results

ALLMedicine™ Kaposi Sarcoma Center

Research & Reviews  763 results

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
https://clinicaltrials.gov/ct2/show/NCT02595866

May 20th, 2022 - PRIMARY OBJECTIVES: I. To assess the safety and tolerability of MK-3475 (pembrolizumab) in HIV-infected patients on effective antiretroviral therapy and with relapsed/refractory or disseminated acquired immune deficiency syndrome (AIDS)-defining o...

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT02659930

May 20th, 2022 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor that most frequently involves skin, but can also involve lymph nodes, lungs and gastrointestinal tract. It is most common in people with HIV or other forms of immune compro...

History of the KSHV Inflammatory Cytokine Syndrome (KICS)
https://clinicaltrials.gov/ct2/show/NCT01419561

May 20th, 2022 - BACKGROUND: KSHV inflammatory cytokine syndrome (KICS) is a newly recognized syndrome caused by Kaposi sarcoma-associated herpesvirus (KSHV). It is characterized by severe inflammatory symptoms including fevers, wasting, cytopenias, hypoalbuminemi...

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis
https://clinicaltrials.gov/ct2/show/NCT04742387

May 20th, 2022 - Title: Assessment of Bone Mineral Density in People Living with HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis Study Description: This is a retrospective review that includes all participants with human immunodeficienc...

CDK4/6 inhibitors sensitize gammaherpesvirus-infected tumor cells to T-cell killing by ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101822
Journal of Translational Medicine; Wu Y, Shrestha P et. al.

May 14th, 2022 - The two oncogenic human gammaherpesviruses, Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV), both downregulate immune surface molecules, such as MHC-I, ICAM-1, and B7-2, enabling them to evade T-cell and natural killer ce...

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Drugs  2 results see all →

Clinicaltrials.gov  18 results

Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer
https://clinicaltrials.gov/ct2/show/NCT02595866

May 20th, 2022 - PRIMARY OBJECTIVES: I. To assess the safety and tolerability of MK-3475 (pembrolizumab) in HIV-infected patients on effective antiretroviral therapy and with relapsed/refractory or disseminated acquired immune deficiency syndrome (AIDS)-defining o...

Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma
https://clinicaltrials.gov/ct2/show/NCT02659930

May 20th, 2022 - Background: Kaposi Sarcoma (KS) is a multicentric angioproliferative tumor that most frequently involves skin, but can also involve lymph nodes, lungs and gastrointestinal tract. It is most common in people with HIV or other forms of immune compro...

History of the KSHV Inflammatory Cytokine Syndrome (KICS)
https://clinicaltrials.gov/ct2/show/NCT01419561

May 20th, 2022 - BACKGROUND: KSHV inflammatory cytokine syndrome (KICS) is a newly recognized syndrome caused by Kaposi sarcoma-associated herpesvirus (KSHV). It is characterized by severe inflammatory symptoms including fevers, wasting, cytopenias, hypoalbuminemi...

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis
https://clinicaltrials.gov/ct2/show/NCT04742387

May 20th, 2022 - Title: Assessment of Bone Mineral Density in People Living with HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis Study Description: This is a retrospective review that includes all participants with human immunodeficienc...

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.
https://clinicaltrials.gov/ct2/show/NCT03296553

Jan 27th, 2022 - Kaposi sarcoma (KS) is a Human Herpes-8 disease, it has been described as an angioproliferative disease mediated by cytokines in an environment of immunodeficiency and thus associated with HIV infection. Its course has been described as unpredicta...

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News  57 results

Indurated Violaceous Lesions on the Face, Trunk, and Legs
https://www.mdedge.com/dermatology/article/251484/nonmelanoma-skin-cancer/indurated-violaceous-lesions-face-trunk-and-legs
Yasmin Khalfe, MD, John Trace Worrell, MD et. al.

Feb 4th, 2022 - The Diagnosis: Kaposi Sarcoma A punch biopsy of a lesion on the right side of the back revealed a diffuse, poorly circumscribed, spindle cell neoplasm of the papillary and reticular dermis with associated vascular and pseudovascular spaces distend.

Pembrolizumab/Lenvatinib Combo Under Investigation in Classic Kaposi Sarcoma
https://www.onclive.com/view/pembrolizumab-lenvatinib-combo-under-investigation-in-classic-kaposi-sarcoma

Nov 9th, 2021 - For patients with classic Kaposi sarcoma who relapse following their first or second line of chemotherapy, treatment options are extremely limited, according to Alice Indini, MD. In an effort to expand options available to this population, the pha...

Dr. Indini on the Rationale for the PULSAR Trial in Classic Kaposi Sarcoma
https://www.onclive.com/view/dr-indini-on-the-rationale-for-the-pulsar-trial-in-classic-kaposi-sarcoma

Sep 27th, 2021 - Alice Indini, MD, medical oncologist, Medical Oncology Unit, Department of Internal Medicine, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, discusses the rationale for the phase 2 PULSAR trial in classic Kaposi sarcoma (...

The 5 Goals of Colonoscopy in Ulcerative Colitis
https://www.medscape.com/viewarticle/950489

May 21st, 2021 - This transcript has been edited for clarity. Hello. I'm Dr Stephen Hanauer from Northwestern University in Chicago, speaking to you today about the role of colonoscopy in the management of ulcerative colitis. There are several indications for perf...

Big Moment for Nanotech: Oncology Therapeutics Poised for a Leap
https://www.onclive.com/view/big-moment-for-nanotech-oncology-therapeutics-poised-for-a-leap

Dec 5th, 2020 - This image depicts nanowire arrays synthesized by researchers at Emory/Georgia Tech Center of Cancer Nanotechnology Excellence. The arrays can be used for biosensing, manipulation of cells, and converting mechanical energy into electricity for pow...

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Patient Education  4 results see all →