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About 224 results

ALLMedicine Orf Virus Center

Research & Reviews  109 results

An Orf Virus-based therapeutic vaccine for the treatment of papillomavirus-induced tumors.
https://doi.org/10.1128/JVI.00398-20
Journal of Virology; Schneider M, Müller M et. al.

May 12th, 2020 - The Orf virus (ORFV) represents a suitable vector for the generation of efficient, prophylactic antiviral vaccines against different pathogens. The present study investigates for the first time the therapeutic application of ORFV vector-based vacc...

Development of a recombinase-aided amplification assay for detection of orf virus.
https://doi.org/10.1016/j.jviromet.2020.113861
Journal of Virological Methods; Wang Y, Cui Y et. al.

Apr 28th, 2020 - Orf, caused by orf virus (ORFV), is an important zoonotic disease that infects goat and sheep, leading to huge economic losses. ORFV can also cause cutaneous lesions in people who come in close contact with the diseased animals. Although accurate ...

Orf Virus VIR Antagonizes p53-Mediated Antiviral Effects to Facilitate Viral Replication.
https://doi.org/10.1089/vim.2019.0189
Viral Immunology; Yan MH, Wang LL et. al.

Apr 21st, 2020 - As a zoonotic disease, ovine contagious pustular dermatitis (Orf) is a serious threat to sheep as well as humans. Orf virus (ORFV) interferon resistance protein (VIR) is the principal virulence protein that encodes a dsRNA-binding protein to inhib...

Establishment and characterization of transformed goat primary cells by expression of s...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894772
PloS One; Yamada Y, Liao GR et. al.

Dec 5th, 2019 - Due to the limited host range of orf virus (ORFV), primary cells derived from its natural hosts, such as goats and sheep, are recommended for isolation and propagation of wild type ORFV. This situation limits the option for the study of virus-host...

Poxviral E3L ortholog (Viral Interferon resistance gene) of orf viruses of sheep and go...
https://doi.org/10.1016/j.cyto.2019.04.001
Cytokine Karki M, Kumar A et. al.

Apr 16th, 2019 - Orf is a contagious disease posing a serious threat to animal and human health. E3L is one of the evolutionarily acquired immunomodulatory proteins present in orf virus (ORFV) and is responsible for conferring resistance to interferons among poxvi...

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Clinicaltrials.gov  113 results

An Orf Virus-based therapeutic vaccine for the treatment of papillomavirus-induced tumors.
https://doi.org/10.1128/JVI.00398-20
Journal of Virology; Schneider M, Müller M et. al.

May 12th, 2020 - The Orf virus (ORFV) represents a suitable vector for the generation of efficient, prophylactic antiviral vaccines against different pathogens. The present study investigates for the first time the therapeutic application of ORFV vector-based vacc...

Development of a recombinase-aided amplification assay for detection of orf virus.
https://doi.org/10.1016/j.jviromet.2020.113861
Journal of Virological Methods; Wang Y, Cui Y et. al.

Apr 28th, 2020 - Orf, caused by orf virus (ORFV), is an important zoonotic disease that infects goat and sheep, leading to huge economic losses. ORFV can also cause cutaneous lesions in people who come in close contact with the diseased animals. Although accurate ...

Orf Virus VIR Antagonizes p53-Mediated Antiviral Effects to Facilitate Viral Replication.
https://doi.org/10.1089/vim.2019.0189
Viral Immunology; Yan MH, Wang LL et. al.

Apr 21st, 2020 - As a zoonotic disease, ovine contagious pustular dermatitis (Orf) is a serious threat to sheep as well as humans. Orf virus (ORFV) interferon resistance protein (VIR) is the principal virulence protein that encodes a dsRNA-binding protein to inhib...

Establishment and characterization of transformed goat primary cells by expression of s...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894772
PloS One; Yamada Y, Liao GR et. al.

Dec 5th, 2019 - Due to the limited host range of orf virus (ORFV), primary cells derived from its natural hosts, such as goats and sheep, are recommended for isolation and propagation of wild type ORFV. This situation limits the option for the study of virus-host...

Poxviral E3L ortholog (Viral Interferon resistance gene) of orf viruses of sheep and go...
https://doi.org/10.1016/j.cyto.2019.04.001
Cytokine Karki M, Kumar A et. al.

Apr 16th, 2019 - Orf is a contagious disease posing a serious threat to animal and human health. E3L is one of the evolutionarily acquired immunomodulatory proteins present in orf virus (ORFV) and is responsible for conferring resistance to interferons among poxvi...

see more →

News  2 results

U.S. agency warns of skin lesions from goats, sheep
https://www.reuters.com/article/us-usa-meat-lesions/u-s-agency-warns-of-skin-lesions-from-goats-sheep-idUSBRE83B1OK20120413

Apr 13th, 2012 - ATLANTA (Reuters) - People can contract skin lesions from goats and sheep infected with the Orf virus through household meat preparation or when slaughtering the animals, a federal agency said on Thursday in a report aimed at doctors in ethnically...

U.S. agency warns of skin lesions from goats, sheep
https://www.reuters.com/article/us-usa-meat-lesions/u-s-agency-warns-of-skin-lesions-from-goats-sheep-idUSBRE83B1OK20120412

Apr 12th, 2012 - ATLANTA (Reuters) - People can contract skin lesions from goats and sheep infected with the Orf virus through household meat preparation or when slaughtering the animals, a federal agency said on Thursday in a report aimed at doctors in ethnically...

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