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About 228,264 results
Effectiveness of a Third Dose of MMR Vaccine for Mumps Outbreak Control.
https://doi.org/10.1056/NEJMoa1703309
The New England Journal of Medicine; Cardemil CV, Dahl RM et. al.

Sep 6th, 2017 - The effect of a third dose of the measles-mumps-rubella (MMR) vaccine in stemming a mumps outbreak is unknown. During an outbreak among vaccinated students at the University of Iowa, health officials implemented a widespread MMR vaccine campaign. We evaluated the effectiveness of a third dose for outbreak control and assessed for waning immunity. Of 20,496 university students who were enrolled ...

Perioperative Timing of Infliximab and the Risk of Serious Infection After Elective Hip...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529262
Arthritis Care & Research; George MD, Baker JF et. al.

Jan 27th, 2017 - The optimal timing of tumor necrosis factor antagonists before elective surgery is unknown. This study evaluated the association between infliximab timing and serious infection after elective hip or knee arthroplasty. A retrospective cohort study evaluated US Medicare patients with rheumatoid arthritis, inflammatory bowel disease, psoriasis, psoriatic arthritis, or ankylosing spondylitis who re...

Snubbed by Scientists, Recognized 20 Years Later
https://www.medscape.com/viewarticle/920939
Medscape

Nov 16th, 2019 - When a team led by pathologist Robert Folberg, MD, noticed that uveal melanoma tumors seemed to organize themselves in packets, and between the packs were unexplained structures, the trajectory of their careers changed. The researchers found that some of the structures were solid and others were hollow, and the empty ones took the shape of channels containing red blood cells. At first, th...

Scientists design device for oral delivery of injections
https://www.nih.gov/news-events/nih-research-matters/scientists-design-device-oral-delivery-injections

Oct 28th, 2019 - Biologic drugs are complex medications produced from living organisms or their parts. They include vaccines and drugs to treat conditions like rheumatoid arthritis, psoriasis, and cancer. Some biologic drugs, like insulin, can only be delivered by injection. If taken by mouth, stomach acid would destroy the drug before it could take effect.

Shingles - Genetics Home Reference - NIH
https://ghr.nlm.nih.gov/condition/shingles

Oct 28th, 2019 - Shingles (also known as herpes zoster) results from infection by the varicella zoster virus. This common virus causes chickenpox (also known as varicella), which is characterized by itchy spots on the skin that cover the whole body and usually occurs in childhood or adolescence. After the body fights the initial infection, the varicella zoster virus remains in nerve cells for the rest of a per...

Foamix Receives FDA Approval of AMZEEQ™ Topical Minocycline Treatment for Millions of Moderate to Severe Acne Sufferers
https://www.foamix.com/news-releases/news-release-details/update-foamix-receives-fda-approval-amzeeqtm-topical-minocycline

Oct 17th, 2019 - Foamix Pharmaceuticals Ltd. (Nasdaq: FOMX) (“Foamix” or the “Company”), a specialty pharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has approved its novel AMZEEQTM (minocycline) topical foam, 4%. AMZEEQ, formerly known as FMX101, is indicated for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in adults and pediatric...

Nail Changes Following a Viral Infection: Photo Quiz
https://www.aafp.org/afp/2019/1015/p497.html
American Family Physician;

Oct 14th, 2019 - A seven-year-old boy presented with abnormal growth of his fingernails that began two weeks prior. He had no other symptoms, including pain or pruritus on his hands or around his nails. He did not have fevers, chills, nausea, vomiting, or change in activity. He had hand-foot-and-mouth disease two months earlier that was diagnosed based on vesicular lesions in his mouth and on his hands and feet...

Acne Vulgaris: Diagnosis and Treatment
https://www.aafp.org/afp/2019/1015/p475.html
American Family Physician;

Oct 14th, 2019 - Acne vulgaris is the most prevalent chronic skin disease in the United States, affecting nearly 50 million people per year, mostly adolescents and young adults. Potential sequelae of acne, such as scarring, dyspigmentation, and low self-esteem, may result in significant morbidity. Typical acne lesions involve the pilosebaceous follicles and the interrelated processes of sebum production, Cutiba...

Esophageal Cancer Treatment (Adult) (PDQ®)–Health Professional Version
https://www.cancer.gov/types/esophageal/hp/adult/esophageal-treatment-pdq

Oct 10th, 2019 - Two histologic types account for the majority of malignant esophageal neoplasms: adenocarcinoma and squamous cell carcinoma. Adenocarcinomas typically start in the lower esophagus and squamous cell carcinoma can develop throughout the esophagus. The epidemiology of these types varies markedly.

National Update on Measles Cases and Outbreaks — United States, January 1–October 1, 2019
https://www.cdc.gov/mmwr/volumes/68/wr/mm6840e2.htm
Morbidity and Mortality Weekly Report; Patel, M. et. al.

Oct 3rd, 2019 - What is already known about this topic? Measles was eliminated in the United States in 2000. High national coverage with measles, mumps, and rubella vaccine and rapid implementation of measles control measures prevent widespread measles transmission. What is added by this report? During January–September 2019, 1,249 U.S. measles cases were reported, the highest annual number since 1992...

FDA approves Aklief for acne on face, trunk
https://www.healio.com/dermatology/acne/news/online/%7Bcc693b23-e6fc-4919-a303-fc14f62279b4%7D/fda-approves-aklief-for-acne-on-face-trunk

Oct 3rd, 2019 - The FDA recently approved Galderma’s topical retinoid cream, known as Aklief, for the treatment of acne vulgaris. Additionally, the company reported positive safety profiles for Aklief in two phase 3 clinical trials on acne of both the face and trunk in patients aged 9 years and older, according to a news release issued by the company.

Hand-Foot-and-Mouth Disease: Rapid Evidence Review
https://www.aafp.org/afp/2019/1001/p408.html
American Family Physician; Saguil, A. et. al.

Sep 30th, 2019 - Hand-foot-and-mouth disease is caused by human enteroviruses and coxsackieviruses. Outbreaks can occur in the spring to fall and are common in North America, and most cases occur in patients younger than 10 years. Hand-foot-and-mouth disease is transmitted by fecal-oral, oral-oral, and respiratory droplet contact. Patients present with a low-grade fever, a maculopapular or papulovesicular rash ...

Screening and Management of the Hyperandrogenic Adolescent
https://www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Adolescent-Health-Care/Screening-and-Management-of-the-Hyperandrogenic-Adolescent

Sep 23rd, 2019 - Although androgen excess can manifest in many ways, the most common and recognizable symptoms are hirsutism and acne. Reports of hirsutism and acne should be taken seriously because of their possible association with medical disorders, their substantial effect on self-esteem and quality of life, and the potential for psychosocial morbidity. In patients with symptoms of androgen excess, the diff...

FDA approves first live, non-replicating vaccine to prevent smallpox and monkeypox
https://www.fda.gov/news-events/press-announcements/fda-approves-first-live-non-replicating-vaccine-prevent-smallpox-and-monkeypox

Sep 23rd, 2019 - The U.S. Food and Drug Administration announced today the approval of Jynneos Smallpox and Monkeypox Vaccine, Live, Non-Replicating, for the prevention of smallpox and monkeypox disease in adults 18 years of age and older determined to be at high risk for smallpox or monkeypox infection. This is the only currently FDA-approved vaccine for the prevention of monkeypox disease.

Psoriatic Arthritis - StatPearls
https://www.ncbi.nlm.nih.gov/books/NBK547710/

Sep 19th, 2019 - Psoriatic arthritis (PsA) is chronic inflammatory arthritis associated with psoriasis (PsO) and found in about 20 to 30% of such patients.[1] It shares many clinical features with other spondyloarthropathies and also rheumatoid arthritis (RA). It is usually seronegative, but a small percentage of patients may be positive for rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibodi...

Scarlet fever changes its spots
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30494-3/fulltext
The Lancet Infectious Diseases;

Sep 9th, 2019 - Historically, the human pathogen Streptococcus pyogenes (group A streptococcus) was a major cause of death as a result of sepsis and fatal epidemics of scarlet fever.1 Despite a decline in the incidence and severity of these toxin-mediated diseases over the past century in high-income countries, group A streptococcus is still among the top ten infectious causes of human mortality, with more tha...

Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(19)30446-3/fulltext
The Lancet;

Sep 9th, 2019 - Since 2014, England has seen increased scarlet fever activity unprecedented in modern times. In 2016, England's scarlet fever seasonal rise coincided with an unexpected elevation in invasive Streptococcus pyogenes infections. We describe the molecular epidemiological investigation of these events.

County of Rockland, New York :: Measles Information
http://rocklandgov.com/departments/health/measles-information/

Aug 25th, 2019 - 2018 - 2019 Measles Outbreak in Rockland County: As of August 26, 2019, there are 312* confirmed reported cases of measles in Rockland County. *On Monday, August 26, 2019, 16 historical cases of measles were added to the current total. These cases occurred between early February 2019 and mid-May 2019.

Childhood Laryngeal Tumors Treatment (PDQ®)–Health Professional Version
https://www.cancer.gov/types/head-and-neck/hp/child/laryngeal-treatment-pdq?cid=eb_govdel

Aug 15th, 2019 - Treatment for children with laryngeal tumors depends upon the type; most are rhabdomyosarcoma and treated with chemotherapy and radiation therapy. Squamous cell carcinoma is managed with surgery and radiation therapy. Get detailed treatment information in this summary for clinicians.

Perfusion Assessment in Critical Limb Ischemia: Principles for Understanding and the Development of Evidence and Evaluation of Devices
https://www.ahajournals.org/doi/pdf/10.1161/CIR.0000000000000708

Aug 11th, 2019 - There are >12 million patients with peripheral artery disease in the United States. The most severe form of peripheral artery disease is critical limb ischemia (CLI). The diagnosis and management of CLI is often challenging. Ethnic differences in comorbidities and presentation of CLI exist. Compared with white patients, black and Hispanic patients have higher prevalence rates of diabetes m...