×
About 2,153 results

ALLMedicine™ Alcohol Dependence Center

Research & Reviews  1,073 results

Sex differences in the neuroanatomy of alcohol dependence: hippocampus and amygdala sub...
https://doi.org/10.1038/s41398-021-01204-1 10.1016/S0140-6736(09)60746-7 10.1097/01.ALC.0000164376.69978.6B 10.3748/wjg.v16.i11.1377 10.1016/j.drugalcdep.2004.02.001 10.1081/ADA-100101893 10.1016/j.neubiorev.2015.08.017 10.1111/j.1530-0277.2011.01540.x 10.1016/j.drugalcdep.2016.12.019 10.1038/509282a 10.1016/S2215-0366(16)00104-8 10.1016/j.neuropharm.2016.11.021 10.1016/S0166-4328(96)02270-X 10.1111/j.1749-6632.1999.tb09282.x 10.1038/s41598-018-21341-w 10.1002/hipo.10155 10.1002/cne.902250112 10.3389/fpsyt.2013.00061 10.1016/j.brainres.2008.02.052 10.1111/j.1530-0277.2011.01613.x 10.1007/s00429-013-0605-8 10.1007/s00429-017-1482-3 10.1016/j.neures.2018.08.002 10.1162/jocn_a_00772 10.1016/j.nicl.2019.101824 10.1016/j.neuroimage.2006.06.013 10.1111/j.1369-1600.2006.00043.x 10.1001/archgenpsychiatry.2011.2026 10.1111/j.1530-0277.2006.00223.x 10.1016/j.pscychresns.2005.05.008 10.1176/appi.ajp.157.5.737 10.1001/archpsyc.56.4.356 10.1111/j.1530-0277.1995.tb01478.x 10.1111/j.1530-0277.1992.tb00698.x 10.1176/appi.ajp.158.2.198 10.1176/appi.ajp.2008.07121877 10.3389/fnagi.2014.00261 10.1016/j.neuroimage.2017.04.046 10.1017/S003329170001031X 10.1016/0741-8329(91)91200-L 10.1016/S0925-4927(02)00084-7 10.1016/j.tox.2013.03.001 10.1006/nimg.1998.0395 10.1016/j.neuroimage.2006.01.021 10.1016/j.neuroimage.2015.04.042 10.1038/nn.3648 10.1093/biomet/73.3.751 10.1016/j.neuroscience.2009.01.013 10.1038/npp.2015.130 10.1523/JNEUROSCI.15-01-00721.1995 10.1111/j.1369-1600.2011.00418.x 10.1176/appi.ajp.158.2.188 10.1176/appi.ajp.2009.09081161 10.4306/pi.2014.11.3.330
Translational Psychiatry; Grace S, Rossetti MG et. al.

Mar 5th, 2021 - Males and females with alcohol dependence have distinct mental health and cognitive problems. Animal models of addiction postulate that the underlying neurobiological mechanisms are partially distinct, but there is little evidence of sex differenc...

A Multimethod Examination of Sensitivity to Reward and Sensitivity to Punishment in Bip...
https://doi.org/10.1159/000512661
Psychopathology Mellick W, Prisciandaro JJ et. al.

Feb 17th, 2021 - Shared neurobehavioral characteristics of bipolar disorder (BD) and alcohol dependence (AD), including heightened sensitivity to reward (SR), may account for high rates of BD and AD co-occurrence (BD + AD). However, empirical research is lacking. ...

Network preservation reveals shared and unique biological processes associated with chr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745987
PloS One; Vornholt E, Drake J et. al.

Dec 17th, 2020 - Chronic alcohol abuse has been linked to the disruption of executive function and allostatic conditioning of reward response dysregulation in the mesocorticolimbic pathway (MCL). Here, we analyzed genome-wide mRNA and miRNA expression from matched...

Identification of Functional Genetic Variants Associated With Alcohol Dependence and Re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725989
Alcoholism, Clinical and Experimental Research; Thapa KS, Chen AB et. al.

Oct 29th, 2020 - Genome-wide association studies (GWAS) of alcohol dependence (AD) and related phenotypes have identified multiple loci, but the functional variants underlying the loci have in most cases not been identified. Noncoding variants can influence phenot...

Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756309
Alcoholism, Clinical and Experimental Research; Drake J, McMichael GO et. al.

Oct 17th, 2020 - Long noncoding RNA (lncRNA) have been implicated in the etiology of alcohol use. Since lncRNA provide another layer of complexity to the transcriptome, assessing their expression in the brain is the first critical step toward understanding lncRNA ...

see more →

Clinicaltrials.gov  1,077 results

Sex differences in the neuroanatomy of alcohol dependence: hippocampus and amygdala sub...
https://doi.org/10.1038/s41398-021-01204-1 10.1016/S0140-6736(09)60746-7 10.1097/01.ALC.0000164376.69978.6B 10.3748/wjg.v16.i11.1377 10.1016/j.drugalcdep.2004.02.001 10.1081/ADA-100101893 10.1016/j.neubiorev.2015.08.017 10.1111/j.1530-0277.2011.01540.x 10.1016/j.drugalcdep.2016.12.019 10.1038/509282a 10.1016/S2215-0366(16)00104-8 10.1016/j.neuropharm.2016.11.021 10.1016/S0166-4328(96)02270-X 10.1111/j.1749-6632.1999.tb09282.x 10.1038/s41598-018-21341-w 10.1002/hipo.10155 10.1002/cne.902250112 10.3389/fpsyt.2013.00061 10.1016/j.brainres.2008.02.052 10.1111/j.1530-0277.2011.01613.x 10.1007/s00429-013-0605-8 10.1007/s00429-017-1482-3 10.1016/j.neures.2018.08.002 10.1162/jocn_a_00772 10.1016/j.nicl.2019.101824 10.1016/j.neuroimage.2006.06.013 10.1111/j.1369-1600.2006.00043.x 10.1001/archgenpsychiatry.2011.2026 10.1111/j.1530-0277.2006.00223.x 10.1016/j.pscychresns.2005.05.008 10.1176/appi.ajp.157.5.737 10.1001/archpsyc.56.4.356 10.1111/j.1530-0277.1995.tb01478.x 10.1111/j.1530-0277.1992.tb00698.x 10.1176/appi.ajp.158.2.198 10.1176/appi.ajp.2008.07121877 10.3389/fnagi.2014.00261 10.1016/j.neuroimage.2017.04.046 10.1017/S003329170001031X 10.1016/0741-8329(91)91200-L 10.1016/S0925-4927(02)00084-7 10.1016/j.tox.2013.03.001 10.1006/nimg.1998.0395 10.1016/j.neuroimage.2006.01.021 10.1016/j.neuroimage.2015.04.042 10.1038/nn.3648 10.1093/biomet/73.3.751 10.1016/j.neuroscience.2009.01.013 10.1038/npp.2015.130 10.1523/JNEUROSCI.15-01-00721.1995 10.1111/j.1369-1600.2011.00418.x 10.1176/appi.ajp.158.2.188 10.1176/appi.ajp.2009.09081161 10.4306/pi.2014.11.3.330
Translational Psychiatry; Grace S, Rossetti MG et. al.

Mar 5th, 2021 - Males and females with alcohol dependence have distinct mental health and cognitive problems. Animal models of addiction postulate that the underlying neurobiological mechanisms are partially distinct, but there is little evidence of sex differenc...

A Multimethod Examination of Sensitivity to Reward and Sensitivity to Punishment in Bip...
https://doi.org/10.1159/000512661
Psychopathology Mellick W, Prisciandaro JJ et. al.

Feb 17th, 2021 - Shared neurobehavioral characteristics of bipolar disorder (BD) and alcohol dependence (AD), including heightened sensitivity to reward (SR), may account for high rates of BD and AD co-occurrence (BD + AD). However, empirical research is lacking. ...

Network preservation reveals shared and unique biological processes associated with chr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7745987
PloS One; Vornholt E, Drake J et. al.

Dec 17th, 2020 - Chronic alcohol abuse has been linked to the disruption of executive function and allostatic conditioning of reward response dysregulation in the mesocorticolimbic pathway (MCL). Here, we analyzed genome-wide mRNA and miRNA expression from matched...

Identification of Functional Genetic Variants Associated With Alcohol Dependence and Re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725989
Alcoholism, Clinical and Experimental Research; Thapa KS, Chen AB et. al.

Oct 29th, 2020 - Genome-wide association studies (GWAS) of alcohol dependence (AD) and related phenotypes have identified multiple loci, but the functional variants underlying the loci have in most cases not been identified. Noncoding variants can influence phenot...

Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756309
Alcoholism, Clinical and Experimental Research; Drake J, McMichael GO et. al.

Oct 17th, 2020 - Long noncoding RNA (lncRNA) have been implicated in the etiology of alcohol use. Since lncRNA provide another layer of complexity to the transcriptome, assessing their expression in the brain is the first critical step toward understanding lncRNA ...

see more →

News  3 results

HCV and alcohol use disorder – bad news for the liver
https://www.mdedge.com/gihepnews/article/167989/hepatitis/hcv-and-alcohol-use-disorder-bad-news-liver
Mark S. Lesney, MDedge News

Jun 13th, 2018 - Patients infected with both hepatitis C virus (HCV) and alcohol use disorder (AUD) were twice as likely to present with advanced liver fibrosis at hospital admission, according to the results of a database study published in Drug and Alcohol Depen.

High-Dose Baclofen Supports Abstinence in Alcoholism
https://www.medscape.com/viewarticle/847201

Jun 29th, 2015 - ATHENS, Greece — High doses of baclofen (multiple brands), a drug normally used to treat spasticity, supports alcohol-dependent patients in maintaining abstinence from alcohol and is reasonably well tolerated, new research indicates. As reported b...

High-Dose Baclofen Supports Abstinence in Alcoholism
https://www.staging.medscape.com/viewarticle/847201

Jun 29th, 2015 - ATHENS, Greece — High doses of baclofen (multiple brands), a drug normally used to treat spasticity, supports alcohol-dependent patients in maintaining abstinence from alcohol and is reasonably well tolerated, new research indicates. As reported b...

see more →