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About 2,848 results

ALLMedicine™ Alcohol Use Disorder Center

Research & Reviews  1,071 results

Mental Health Correlates of Probable Posttraumatic Stress Disorder, Probable Alcohol Us...
https://doi.org/10.1177/01454455211033517
Behavior Modification; Zegel M, Lebeaut A et. al.

Jul 30th, 2021 - Firefighters demonstrate high rates of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD). Research has yet to compare how these diagnoses and their co-occurrence relate to firefighter mental health. This study evaluated trauma lo...

Brain-specific inhibition of mTORC1 eliminates side effects resulting from mTORC1 block...
https://doi.org/10.1038/s41467-021-24567-x 10.1001/jamapsychiatry.2017.2161 10.1016/S0140-6736(19)31775-1 10.1016/j.neuron.2014.09.034 10.1016/j.cell.2017.03.035 10.1038/s41580-019-0199-y 10.1172/JCI73939 10.7554/eLife.51333 10.1146/annurev-neuro-071013-014100 10.1016/B978-0-12-420170-5.00005-2 10.1038/nn.3546 10.1038/nature11861 10.1038/nrn3068 10.1111/jnc.12725 10.1038/nrn.2016.85 10.1073/pnas.1005554107 10.1111/adb.12464 10.1016/j.bbapap.2009.12.001 10.1038/nature17963 10.1111/adb.12528 10.1523/JNEUROSCI.2254-15.2016 10.1038/nn.3439 10.1111/adb.12653 10.1056/NEJMra1511480 10.1177/152692480101100105 10.1016/j.cmet.2014.01.001 10.1038/nrd3531 10.1097/TP.0b013e3182551021 10.1073/pnas.92.11.4947 10.1016/j.cmet.2014.05.001 10.1016/j.cmet.2013.02.008 10.2337/db09-1324 10.1016/j.alcohol.2014.01.006 10.1016/j.biopsych.2017.06.004 10.1007/s00213-018-4882-z 10.1038/s41467-020-18114-3 10.1016/j.neuropharm.2016.01.010 10.1016/j.nlm.2007.12.004 10.1016/j.nlm.2013.08.014 10.1016/j.ccell.2017.01.014 10.1016/j.cell.2013.03.028 10.1073/pnas.1522054113 10.1038/s41467-019-11174-0 10.1016/j.biopsych.2015.06.007 10.1038/nprot.2013.155 10.1038/tp.2013.4 10.1016/j.neuron.2017.08.037
Nature Communications; Ehinger Y, Zhang Z et. al.

Jul 29th, 2021 - Alcohol Use Disorder (AUD) affects a large portion of the population. Unfortunately, efficacious medications to treat the disease are limited. Studies in rodents suggest that mTORC1 plays a crucial role in mechanisms underlying phenotypes such as ...

Gender Differences in Psychiatric and Behavioral Health Burden Among Adults With Alcoho...
https://doi.org/10.1097/ADM.0000000000000890
Journal of Addiction Medicine; Rhee TG, Rosenheck RA

Jul 27th, 2021 - Studies report that women with opioid use disorder experience more comorbid psychiatric disorders and behavioral health burdens than men. We broadened the study of this phenomenon to alcohol use disorder (AUD) and other substance use disorders (SU...

Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmac...
https://doi.org/10.1038/s41386-021-01097-0 10.1016/S2215-0366(18)30337-7 10.1111/acer.13093 10.1080/17425255.2019.1628218 10.1016/j.psychres.2015.09.019 10.1001/jama.2014.3628 10.1111/j.1360-0443.2004.00763.x 10.1177/0269881107078308 10.1111/j.1360-0443.2012.04054.x 10.1111/j.1530-0277.2007.00536.x 10.2147/TCRM.S23184 10.1136/bmj.m3934 10.1016/j.pharmthera.2006.02.001 10.1111/add.12557 10.1007/s00213-004-1991-7 10.1111/acer.12541 10.1111/acer.14233 10.1038/ng761 10.1146/annurev.genom.6.080604.162315 10.1038/mp.2012.13 10.1002/cpt.1489 10.2174/138161210791516387 10.1111/j.1530-0277.2010.01170.x 10.1001/archpsyc.65.2.135 10.1038/tpj.2010.51 10.1038/tp.2014.103 10.1038/nm1163 10.1038/mp.2017.153 10.1016/j.copsyc.2018.07.012 10.1038/s41467-019-09480-8 10.1038/s41593-018-0275-1 10.1038/s41593-020-0643-5 10.1038/s41588-018-0307-5 10.1038/s41562-019-0557-y 10.1093/ntr/ntx107 10.1111/add.14032 10.1001/jama.295.17.2003 10.1111/j.1530-0277.2008.00884.x 10.1093/bioinformatics/btq340 10.1002/gepi.22339 10.1111/nyas.14002 10.1177/002215540104900409 10.1038/mp.2017.97 10.1210/js.2019-00158 10.1038/s41588-019-0481-0 10.1038/sj.npp.1301494 10.1371/journal.pone.0037999 10.1016/j.pbb.2009.07.019 10.1152/physiolgenomics.00184.2005 10.2119/molmed.2015.00017 10.1073/pnas.1720446115 10.1038/s41398-020-01121-9 10.1016/j.pnpbp.2017.01.011 10.1371/journal.pone.0203896 10.1038/nature19057
Neuropsychopharmacology : Official Publication of the Ame... Biernacka JM, Coombes BJ et. al.

Jul 25th, 2021 - Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit from these treatments. Here we present the first genome-wide association study of AUD trea...

Repeated, moderate footshock reduces the propensity to relapse to alcohol seeking in fe...
https://doi.org/10.1037/bne0000486
Behavioral Neuroscience; Campbell EJ, Maddern XJ et. al.

Jul 23rd, 2021 - Persistent alcohol use despite negative consequences is a key feature of alcohol use disorder (AUD) and is typically assessed using punishment in animal models. This study examined relapse-like behavior in male and female alcohol-preferring iP rat...

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Guidelines  1 results

Diagnosis and treatment of acute alcohol intoxication and alcohol withdrawal syndrome: ...
https://doi.org/10.1007/s11739-018-1933-8
Internal and Emergency Medicine; Caputo F, Agabio R et. al.

Sep 7th, 2018 - The chronic use of alcohol can lead to the onset of an alcohol use disorder (AUD). About 50% of subjects with an AUD may develop alcohol withdrawal syndrome (AWS) when they reduce or discontinue their alcohol consumption and, in 3-5% of them, conv...

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Clinicaltrials.gov  26 results

Nicotinic Receptor Genetic Variation and Alcohol Reward
https://clinicaltrials.gov/ct2/show/NCT03294460

May 4th, 2020 - Objectives: Alcohol use disorder (AUD) is a chronic disease that has a tremendously negative impact on individuals and their families and a substantial burden on society. Research on quantitative endophenotypes such as alcohol response, and their ...

Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics
https://clinicaltrials.gov/ct2/show/NCT03220776

Mar 17th, 2020 - Bipolar disorder (BD) is the Axis I psychiatric condition most strongly associated with substance use disorder (SUD); diagnostic co-occurrence is particularly high between BD and alcohol use disorder (AUD). Individuals with co-occurring SUD and BD...

Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
https://clinicaltrials.gov/ct2/show/NCT03667846

Mar 11th, 2020 - Alcohol use disorder (AUD) and post-traumatic stress disorder (PTSD) are highly comorbid, and present a clinical challenge for which existing treatments have limited efficacy. Existing clinical evidence suggests treatments that simultaneously addr...

N-Acetylcysteine for Adolescent Alcohol Use Disorder
https://clinicaltrials.gov/ct2/show/NCT03707951

Mar 4th, 2020 - Adolescence is a critical developmental stage involving marked elevation in alcohol initiation, progression to AUD, and development of significant, lasting adverse outcomes from use. Effective treatments must be developed for AUD in this especiall...

Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial
https://clinicaltrials.gov/ct2/show/NCT03660124

Mar 3rd, 2020 - This is a phase I, non-blinded, non-randomized, pilot trial for safety and efficacy of DBS for AUD. Patients who meet inclusion and exclusion criteria will be identified and recruited from the practices of Sunnybrook psychiatrists. Five (5) to ten...

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News  35 results

Naltrexone Cuts Hospitalization, Deaths in Alcohol Use Disorder
https://www.medscape.com/viewarticle/944535

Jan 22nd, 2021 - Naltrexone reduces the risk for hospitalization for alcohol use disorder (AUD), regardless of whether it is used alone or in conjunction with disulfiram or acamprosate, new research suggests. Investigators analyzed 10-year data on more than 125,00...

Fast Five Quiz: Alcohol Use Disorder
https://reference.medscape.com/viewarticle/936600_1

Sep 2nd, 2020 - Alcohol use is the third-leading cause of preventable death in the United States. The World Health Organization (WHO) estimates that the harmful use of alcohol results in about 3 million deaths worldwide each year, which is 5.3% of all deaths. Alc...

Fast Five Quiz: Alcohol Use Disorder
https://reference.medscape.com/viewarticle/936600

Sep 2nd, 2020 - Alcohol use is the third-leading cause of preventable death in the United States. The World Health Organization (WHO) estimates that the harmful use of alcohol results in about 3 million deaths worldwide each year, which is 5.3% of all deaths. Alc...

Reframing Alcohol Abuse as Treatable Cuts Stigma
https://www.medscape.com/viewarticle/930047

May 6th, 2020 - As alcohol-related death and disease rates rise, framing alcohol use disorder as a treatable disease with neurobiologic underpinnings might help reduce the stigma that many patients endure, according to George F. Koob, PhD, director of the Nationa...

Reframing Alcohol Abuse as Treatable Cuts Stigma
https://www.staging.medscape.com/viewarticle/930047

May 6th, 2020 - As alcohol-related death and disease rates rise, framing alcohol use disorder as a treatable disease with neurobiologic underpinnings might help reduce the stigma that many patients endure, according to George F. Koob, PhD, director of the Nationa...

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Patient Education  6 results see all →