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About 413 results

ALLMedicine™ Alcohol Dependence Center

Research & Reviews  162 results

Predicting Alcohol Dependence Symptoms by Young Adulthood: A Co-Twin Comparisons Study.
https://doi.org/10.1017/thg.2021.36
Twin Research and Human Genetics : the Official Journal O... Stephenson M, Barr P et. al.

Sep 17th, 2021 - Co-twin comparisons address familial confounding by controlling for genetic and environmental influences that twin siblings share. We applied the co-twin comparison design to investigate associations of adolescent factors with alcohol dependence (...

Baseline severity and the prediction of placebo response in clinical trials for alcohol...
https://doi.org/10.1111/acer.14670
Alcoholism, Clinical and Experimental Research; Scherrer B, Guiraud J et. al.

Aug 22nd, 2021 - There is considerable unexplained variability in alcohol abstinence rates (AR) in the placebo groups of randomized controlled trials (RCTs) for alcohol dependence (AD). This is of particular interest because placebo responses correlate negatively ...

Combinations of alcohol-induced flushing with genetic polymorphisms of alcohol and alde...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312924
PloS One; Yokoyama A, Yokoyama T et. al.

Jul 27th, 2021 - The risk of alcohol dependence (AD) in Japanese men and women was evaluated according to combinations of alcohol flushing and aldehyde dehydrogenase-2 (ALDH2, rs671) and alcohol dehydrogenase-1B (ADH1B, rs1229984) genotypes, all of which are known...

Identifying a novel biological mechanism for alcohol addiction associated with circRNA ...
https://doi.org/10.1111/adb.13071
Addiction Biology; Vornholt E, Drake J et. al.

Jun 25th, 2021 - Our lab and others have shown that chronic alcohol use leads to gene and miRNA expression changes across the mesocorticolimbic (MCL) system. Circular RNAs (circRNAs) are noncoding RNAs that form closed-loop structures and are reported to alter gen...

Efficacy and tolerability of baclofen in a U.S. community population with alcohol use d...
https://doi.org/10.1038/s41386-021-01055-w 10.1001/jamapsychiatry.2015.0584 10.1016/S0376-8716(03)00134-0 10.1001/jama.2014.3628 10.1016/S2215-0366(16)00104-8 10.1001/jamainternmed.2013.11950 10.1111/j.1530-0277.2001.tb02356.x 10.1016/j.euroneuro.2018.03.017 10.1111/acps.12905 10.1111/add.14191 10.3389/fpsyt.2012.00103 10.1016/S0140-6736(07)61814-5 10.1192/bjp.2018.13 10.1016/S2215-0366(18)30303-1 10.1111/j.1530-0277.2010.01273.x 10.1111/add.13787 10.1007/s00213-014-3652-9 10.1111/j.1360-0443.1988.tb00485.x 10.1111/j.1530-0277.1999.tb04349.x 10.15288/jsas.2005.s15.170 10.1111/j.1530-0277.2010.01290.x 10.1001/archpsyc.1993.01820210073009 10.1001/jamapsychiatry.2016.2157 10.1037/1082-989X.2.1.64 10.1016/j.jsat.2006.09.008 10.1093/alcalc/37.5.504 10.1001/jama.295.17.2003 10.1016/j.jpsychires.2006.02.002 10.1093/alcalc/agv052 10.1007/s00213-014-3652-9 10.1002/jhm.928 10.1016/j.amjmed.2005.08.042 10.1016/j.amjmed.2006.03.015 10.1007/s00213-018-4893-9 10.1016/j.alcohol.2012.11.002 10.1007/s40263-018-0596-3 10.1016/j.euroneuro.2016.10.006
Neuropsychopharmacology : Official Publication of the Ame... Garbutt JC, Kampov-Polevoy AB et. al.

Jun 23rd, 2021 - Identification of new medications for alcohol use disorder (AUD) is important for improving treatment options. Baclofen, a GABAB agonist, has been identified as a potential pharmacotherapy for AUD. In a 16-week double-blind, randomized, placebo-co...

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News  3 results

HCV and alcohol use disorder – bad news for the liver
https://www.mdedge.com/gihepnews/article/167989/hepatitis/hcv-and-alcohol-use-disorder-bad-news-liver
Mark S. Lesney, MDedge News

Jun 13th, 2018 - Patients infected with both hepatitis C virus (HCV) and alcohol use disorder (AUD) were twice as likely to present with advanced liver fibrosis at hospital admission, according to the results of a database study published in Drug and Alcohol Depen.

High-Dose Baclofen Supports Abstinence in Alcoholism
https://www.medscape.com/viewarticle/847201

Jun 30th, 2015 - ATHENS, Greece — High doses of baclofen (multiple brands), a drug normally used to treat spasticity, supports alcohol-dependent patients in maintaining abstinence from alcohol and is reasonably well tolerated, new research indicates. As reported b...

High-Dose Baclofen Supports Abstinence in Alcoholism
https://www.staging.medscape.com/viewarticle/847201

Jun 30th, 2015 - ATHENS, Greece — High doses of baclofen (multiple brands), a drug normally used to treat spasticity, supports alcohol-dependent patients in maintaining abstinence from alcohol and is reasonably well tolerated, new research indicates. As reported b...

see more →