×
About 513 results

ALLMedicine™ Cocaine Center

Research & Reviews  187 results

Patterns of reduced use and abstinence in multi-site randomized controlled trials of ph...
https://doi.org/10.1016/j.drugalcdep.2021.108904
Drug and Alcohol Dependence; Amin-Esmaeili M, Susukida R et. al.

Jul 26th, 2021 - Many individuals with cocaine or methamphetamine use disorders who enter treatment do not achieve abstinence but reduce their use of the target drug. We aimed to compare change in pattern of drug use (i.e., achieving "abstinence", "reduced use" or...

Understanding opioid overdose risk and response preparedness among people who use cocai...
https://doi.org/10.1080/08897077.2021.1946893
Substance Abuse; Hughto JMW, Gordon LK et. al.

Jul 7th, 2021 - Fatal overdoses involving cocaine (powdered or crack) and fentanyl have increased nationally and in Massachusetts. It is unclear how overdose risk and preparedness to respond to an overdose differs by patterns of cocaine and opioid use. Methods: F...

A Single Method for 127 Recommended and Additional DUID Drugs in Blood and Urine by LC-...
https://doi.org/10.1093/jat/bkab075
Journal of Analytical Toxicology; Farley M, Tran H et. al.

Jun 24th, 2021 - Driving under the influence of drugs (DUID) cases continue to challenge forensic toxicologists as both the volume and complexity of casework increases. Comprehensive DUID testing should also meet the drafted ASB/ANSI standard and the NSC-ADID reco...

Sustained splenic contraction after daily cocaine administration in rats.
https://doi.org/10.1371/journal.pone.0252853
PloS One; Nomura M, Unuma K et. al.

Jun 5th, 2021 - The purpose of this study is to examine the effect of repeated cocaine administration on the whole body of rats. Rats (male, 6 weeks old, Sprague Dawley) were injected intraperitoneally with cocaine (50 mg/kg) once a day for 1, 3 or 7 days, and ma...

Atypical presentation of Takayasu aortitis and myocarditis contributing to sudden death...
https://doi.org/10.1016/j.carpath.2021.107347
Cardiovascular Pathology : the Official Journal of the So... Ferreira EO, MacDonald JK et. al.

May 27th, 2021 - This is a rare presentation of Takayasu arteritis in a 30-year-old Canadian First Nations woman with cardiac and aortic root-predominant disease, which manifested in complete heart block. She had a past medical history significant for substance mi...

see more →

Clinicaltrials.gov  14 results

Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
https://clinicaltrials.gov/ct2/show/NCT01376570

Apr 20th, 2018 - Using a randomized controlled study design, the investigators will test the efficacy of an abstinence-reinforcing contingency management intervention compared with a control condition (Performance Feedback) on HIV viral load suppression. The inves...

Pharmacogenetics of Disulfiram for Cocaine
https://clinicaltrials.gov/ct2/show/NCT00149630

Mar 15th, 2017 - Dopamine, a type of neurotransmitter, is the brain's "feel good" chemical. The amount of dopamine in the body may be an important factor in how cocaine addicts respond to treatment. Disulfiram, like cocaine, enhances dopamine activity. Upon taking...

Metabolic Effects of Cocaine
https://clinicaltrials.gov/ct2/show/NCT00451230

Jan 18th, 2017 - The goal of this this study is to elucidate the role of the HPA axis in the pathophysiology of cocaine dependence

Stress Hormones and Human Cocaine Use - 7
https://clinicaltrials.gov/ct2/show/NCT00000290

Jan 12th, 2017 - The goal of this study was to investigate the role of sympathetic-adrenal medullary (SAM) and hy0pothalamo-pituitary-adrenal (HPA) systems in mediating the addictive effects of cocaine. A toal of 6 male subjects were enrolled for this 5 day inpati...

Acute Withdrawal From Smoked Cocaine - 9
https://clinicaltrials.gov/ct2/show/NCT00000292

Jan 12th, 2017 - Although there are clearly identifiable withdrawal syndromes following cessation of a number of abused drugs such as alcohol and heroin, it is unclear whether a withdrawal syndrome follows the cessation of crack cocaine. A laboratory model of with...

see more →

News  4 results

Substance Abuse: Good News, Not So Good News
https://www.mdedge.com/fedprac/article/106251/addiction-medicine/substance-abuse-good-news-not-so-good-news
Jan Dyer

Jan 21st, 2016 - Admissions to publicly funded substance abuse treatment have declined slightly for alcohol abuse and markedly for cocaine use, according to a new report from the Substance Abuse and Mental Health Services Administration (SAMHSA). Related The Stati.

Heroin Use Rising in the US
https://www.medscape.com/viewarticle/843761

Apr 27th, 2015 - Heroin use in the United States, though still uncommon relative to the use of other illicit substances, has risen significantly since 2002, a new report indicates. Rachel Lipari, PhD, and Arthur Hughes, from the Substance Abuse and Mental Health S...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223_1

Jan 29th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223

Jan 29th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

see more →