×
About 2,368 results

ALLMedicine™ Cocaine Center

Research & Reviews  1,179 results

Shifts in the neurobiological mechanisms motivating cocaine use with the development of...
https://doi.org/10.1007/s00213-020-05732-4
Psychopharmacology Lynch WJ, Bakhti-Suroosh A et. al.

Nov 26th, 2020 - The development of addiction is accompanied by a shift in the mechanisms motivating cocaine use from nucleus accumbens (NAc) dopamine D1 receptor (D1R) signaling to glutamate AMPA-kainate receptor (AMPA-R) signaling. Here, we determined whether si...

Oral HPV among people who use crack-cocaine: prevalence, genotypes, risk factors, and k...
https://doi.org/10.1007/s00784-020-03698-3
Clinical Oral Investigations; Rodrigues MSA, Nascimento RS et. al.

Nov 22nd, 2020 - This study estimated the prevalence, genotype distribution, and the factors associated with oral human papillomavirus (HPV) in people who use crack-cocaine (PWUCC) in a remote Brazilian region. This cross-sectional study used community-based snowb...

Increased negative affect when combining early-life maternal deprivation with adolescen...
https://doi.org/10.1007/s00213-020-05689-4
Psychopharmacology Bis-Humbert C, García-Cabrerizo R et. al.

Oct 28th, 2020 - Besides early drug initiation during adolescence, another vulnerability factor associated with increased risk for substance abuse later in life is early-life stress. One way of assessing such combined risk is by evaluating the emergence of increas...

The orexin (hypocretin) neuropeptide system is a target for novel therapeutics to treat...
https://doi.org/10.1016/j.neuropharm.2020.108359
Neuropharmacology James MH, Fragale JE et. al.

Oct 22nd, 2020 - An estimated 50-90% of individuals with cocaine use disorder (CUD) also report using alcohol. Cocaine users report coabusing alcohol to 'self-medicate' against the negative emotional side effects of the cocaine 'crash', including the onset of anxi...

Risperidone and 5-HT2A receptor antagonists attenuate and reverse cocaine-induced hyper...
https://doi.org/10.1093/ijnp/pyaa065
The International Journal of Neuropsychopharmacology; Okada T, Shioda K et. al.

Aug 20th, 2020 - Cocaine (benzoylmethylecgonine) is one of the most widely used illegal psychostimulant drugs used worldwide, and mortality from acute intoxication is increasing. Suppressing hyperthermia is effective in reducing cocaine-related mortality, but a de...

see more →

Clinicaltrials.gov  1,185 results

Shifts in the neurobiological mechanisms motivating cocaine use with the development of...
https://doi.org/10.1007/s00213-020-05732-4
Psychopharmacology Lynch WJ, Bakhti-Suroosh A et. al.

Nov 26th, 2020 - The development of addiction is accompanied by a shift in the mechanisms motivating cocaine use from nucleus accumbens (NAc) dopamine D1 receptor (D1R) signaling to glutamate AMPA-kainate receptor (AMPA-R) signaling. Here, we determined whether si...

Oral HPV among people who use crack-cocaine: prevalence, genotypes, risk factors, and k...
https://doi.org/10.1007/s00784-020-03698-3
Clinical Oral Investigations; Rodrigues MSA, Nascimento RS et. al.

Nov 22nd, 2020 - This study estimated the prevalence, genotype distribution, and the factors associated with oral human papillomavirus (HPV) in people who use crack-cocaine (PWUCC) in a remote Brazilian region. This cross-sectional study used community-based snowb...

Increased negative affect when combining early-life maternal deprivation with adolescen...
https://doi.org/10.1007/s00213-020-05689-4
Psychopharmacology Bis-Humbert C, García-Cabrerizo R et. al.

Oct 28th, 2020 - Besides early drug initiation during adolescence, another vulnerability factor associated with increased risk for substance abuse later in life is early-life stress. One way of assessing such combined risk is by evaluating the emergence of increas...

The orexin (hypocretin) neuropeptide system is a target for novel therapeutics to treat...
https://doi.org/10.1016/j.neuropharm.2020.108359
Neuropharmacology James MH, Fragale JE et. al.

Oct 22nd, 2020 - An estimated 50-90% of individuals with cocaine use disorder (CUD) also report using alcohol. Cocaine users report coabusing alcohol to 'self-medicate' against the negative emotional side effects of the cocaine 'crash', including the onset of anxi...

Risperidone and 5-HT2A receptor antagonists attenuate and reverse cocaine-induced hyper...
https://doi.org/10.1093/ijnp/pyaa065
The International Journal of Neuropsychopharmacology; Okada T, Shioda K et. al.

Aug 20th, 2020 - Cocaine (benzoylmethylecgonine) is one of the most widely used illegal psychostimulant drugs used worldwide, and mortality from acute intoxication is increasing. Suppressing hyperthermia is effective in reducing cocaine-related mortality, but a de...

see more →

News  4 results

Substance Abuse: Good News, Not So Good News
https://www.mdedge.com/fedprac/article/106251/addiction-medicine/substance-abuse-good-news-not-so-good-news
Jan Dyer

Jan 21st, 2016 - Admissions to publicly funded substance abuse treatment have declined slightly for alcohol abuse and markedly for cocaine use, according to a new report from the Substance Abuse and Mental Health Services Administration (SAMHSA). Related The Stati.

Heroin Use Rising in the US
https://www.medscape.com/viewarticle/843761

Apr 26th, 2015 - Heroin use in the United States, though still uncommon relative to the use of other illicit substances, has risen significantly since 2002, a new report indicates. Rachel Lipari, PhD, and Arthur Hughes, from the Substance Abuse and Mental Health S...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223_1

Jan 28th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223

Jan 28th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

see more →