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About 458 results

ALLMedicine™ Cocaine Center

Research & Reviews  179 results

A systematic review of addiction substitution in recovery: Clinical lore or empirically...
https://doi.org/10.1016/j.cpr.2021.102083
Clinical Psychology Review; Kim HS, Hodgins DC et. al.

Sep 19th, 2021 - This systematic review synthesized the literature examining addiction substitution during recovery from substance use or behavioral addictions. A total of 96 studies were included with sample sizes ranging from 6 to 14,885. The most common recover...

Ca2+ channel blockade reduces cocaine's vasoconstriction and neurotoxicity in the prefr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421405
Translational Psychiatry; Du C, Park K et. al.

Sep 8th, 2021 - Cocaine profoundly affects both cerebral blood vessels and neuronal activity in the brain. The vasoconstrictive effects of cocaine, concurrently with its effects on neuronal [Ca2+]i accumulation are likely to jeopardize neuronal tissue that in the...

Diazepam attenuates the effects of cocaine on locomotion, 50-kHz ultrasonic vocalizatio...
https://doi.org/10.1111/bph.15658
British Journal of Pharmacology; Sanchez WN, Pochapski JA et. al.

Aug 15th, 2021 - Currently, there is no effective drug to treat cocaine-use disorder, which affects millions of people worldwide. Benzodiazepines are potential therapeutic candidates, as microdialysis and voltammetry studies have shown that they can decrease dopam...

Residual deficits in functional brain activity after chronic cocaine self-administratio...
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Neuropsychopharmacology : Official Publication of the Ame... Porrino LJ, Smith HR et. al.

Aug 14th, 2021 - Previous studies in humans and in animals have shown dramatic effects of cocaine on measures of brain function that persist into abstinence. The purpose of this study was to examine the neurobiological consequences of abstinence from cocaine, usin...

Linking of NMDA receptors and mGluR5 in the nucleus accumbens core to repeated cocaine-...
https://doi.org/10.1111/adb.13084
Addiction Biology; Sohn S, Kim S et. al.

Aug 12th, 2021 - Rats express a positive emotional state by emitting 50-kHz ultrasonic vocalization (USV) calls in response to drug exposure. This study demonstrated the linking of glutamate receptors in the nucleus accumbens (NAc) to vocal expression of 50-kHz US...

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News  4 results

Substance Abuse: Good News, Not So Good News
https://www.mdedge.com/fedprac/article/106251/addiction-medicine/substance-abuse-good-news-not-so-good-news
Jan Dyer

Jan 21st, 2016 - Admissions to publicly funded substance abuse treatment have declined slightly for alcohol abuse and markedly for cocaine use, according to a new report from the Substance Abuse and Mental Health Services Administration (SAMHSA). Related The Stati.

Heroin Use Rising in the US
https://www.medscape.com/viewarticle/843761

Apr 27th, 2015 - Heroin use in the United States, though still uncommon relative to the use of other illicit substances, has risen significantly since 2002, a new report indicates. Rachel Lipari, PhD, and Arthur Hughes, from the Substance Abuse and Mental Health S...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223_1

Jan 29th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223

Jan 29th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

see more →