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ALLMedicine™ Cocaine Center

Research & Reviews  218 results

White matter microstructure differences in individuals with dependence on cocaine, meth...
https://doi.org/10.1016/j.drugalcdep.2021.109185
Drug and Alcohol Dependence; Ottino-González J, Uhlmann A et. al.

Dec 4th, 2021 - Nicotine and illicit stimulants are very addictive substances. Although associations between grey matter and dependence on stimulants have been frequently reported, white matter correlates have received less attention. Eleven international sites a...

Methylation of the serotonin transporter gene moderates the depressive subjective effec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671356
Behavioural Brain Research; Longtain RB, Graham DP et. al.

Nov 20th, 2021 - Genetic variation in the serotonin transporter (SLC6A4) has been shown to moderate the acute subjective effects of cocaine. Methylation of the SLC6A4 gene is associated with decreased transcription of the serotonin transporter, leading to increase...

Characterization of the Brain Functional Architecture of Psychostimulant Withdrawal Usi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8570684
ENeuro Kimbrough A, Kallupi M et. al.

Sep 29th, 2021 - Numerous brain regions have been identified as contributing to withdrawal behaviors, but it is unclear the way in which these brain regions as a whole lead to withdrawal. The search for a final common brain pathway that is involved in withdrawal r...

A systematic review of addiction substitution in recovery: Clinical lore or empirically...
https://doi.org/10.1016/j.cpr.2021.102083
Clinical Psychology Review; Kim HS, Hodgins DC et. al.

Sep 19th, 2021 - This systematic review synthesized the literature examining addiction substitution during recovery from substance use or behavioral addictions. A total of 96 studies were included with sample sizes ranging from 6 to 14,885. The most common recover...

Ca2+ channel blockade reduces cocaine's vasoconstriction and neurotoxicity in the prefr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421405
Translational Psychiatry; Du C, Park K et. al.

Sep 8th, 2021 - Cocaine profoundly affects both cerebral blood vessels and neuronal activity in the brain. The vasoconstrictive effects of cocaine, concurrently with its effects on neuronal [Ca2+]i accumulation are likely to jeopardize neuronal tissue that in the...

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News  3 results

Heroin Use Rising in the US
https://www.medscape.com/viewarticle/843761

Apr 27th, 2015 - Heroin use in the United States, though still uncommon relative to the use of other illicit substances, has risen significantly since 2002, a new report indicates. Rachel Lipari, PhD, and Arthur Hughes, from the Substance Abuse and Mental Health S...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223

Jan 29th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

Drug Abuse Among Doctors: Easy, Tempting, and Not Uncommon
https://www.medscape.com/viewarticle/819223_1

Jan 29th, 2014 - Tomorrow -- Tomorrow, I Will Stop That's what Marc Myer, a family practice physician in Minnesota, told himself each day as he stole prescription opiates from his patients to feed his addiction. But for Dr. Myer and many physicians like him, "tomo...

see more →