About 282 results
Association Between Marijuana Use and Risk of Cancer: A Systematic Review and Meta-analysis
JAMA Network Open; Ghasemiesfe M, et al

Nov 26th, 2019 - What is the association between marijuana use and cancer development in adults with at least 1 joint-year exposure (equivalent to 1 joint per day for 1 year)?

Association Between Recreational Marijuana Legalization in the United States and Changes in Marijuana Use and Cannabis Use Disorder From 2008 to 2016
JAMA Psychiatry; Cerda M, et al

Nov 12th, 2019 - This study’s findings suggest that possible increases in the risk for cannabis use disorder among adolescent users and increases in frequent use and cannabis use disorder among adults after legalization of recreational marijuana use may raise public health concerns and warrant ongoing study.

Millions of Americans have a substance use disorder. Help is available.

Nov 5th, 2019 - The Substance Abuse and Mental Health Services Administration (SAMHSA) collects information on thousands of state-licensed providers who specialize in treating substance use disorders, addiction, and mental illness.

Smoking & Tobacco Use For Healthcare Providers

Oct 10th, 2019 - CDC investigates outbreak of severe lung disease in patients who have recently used e-cigarette products, also known as “vaping.

E-Cigarettes and Vaping-Related Disease
New England Journal of Medicine;

Oct 1st, 2019 - The use of e-cigarettes has increased rapidly. Although vaping has been shown to assist with smoking cessation, cases of severe vaping-related pulmonary disease and a number of deaths have recently been reported. Here we present a collection of articles and other resources on e-cigarettes and vaping-related disease, including clinical reports and commentary.

Alarming number of heart infections tied to opioid epidemic

Sep 17th, 2019 - An alarming number of people nationwide are developing infections of either the heart’s inner lining or valves, known as infective endocarditis, in large part, due to the current opioid epidemic. This new trend predominantly affects young, white, poor men who also have higher rates of HIV, hepatitis C and alcohol abuse, according to new research published in the Journal of the American Heart As...

Urinary Incontinence in Women: Evaluation and Management
American Family Physician;

Sep 14th, 2019 - Urinary incontinence is a common problem among women worldwide, resulting in a substantial economic burden and decreased quality of life. The Women's Preventive Services Initiative is the only major organization that recommends annual screening for urinary incontinence in all women despite low to insufficient evidence regarding effectiveness and accuracy of methods. No other major organization ...

U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain

Aug 28th, 2019 - This Surgeon General Advisory emphasizes the importance of protecting the U.S. from the health risks of marijuana use in adolescence and during pregnancy.

Interventions to increase adherence to medications for tobacco dependence
Cochrane Database of Systematic Reviews;

Aug 15th, 2019 - Background Pharmacological treatments for tobacco dependence, such as nicotine replacement therapy (NRT), have been shown to be safe and effective interventions for smoking cessation. Higher levels of adherence to these medications increase the likelihood of sustained smoking cessation, but many smokers use them at a lower dose and for less time than is optimal. It is important to determine th...

Electronic Cigarettes: Common Questions and Answers
American Family Physician;

Aug 14th, 2019 - Electronic cigarettes (e-cigarettes) are popular devices designed to heat a liquid solution, often containing nicotine, that generates an inhaled aerosol, or vapor. e-Cigarettes have been marketed as healthier alternatives to traditional cigarettes. Thus, most adult users are current or former smokers who use e-cigarettes to reduce or quit cigarette smoking. Switching completely from cigarettes...

FDA releases long-awaited graphic cigarette warnings

Aug 14th, 2019 - American Heart Association CEO Nancy Brown issued the following response to the proposed cigarette warning labels released today by the Food and Drug Administration (FDA): “The new, graphic cigarette warning labels proposed today by the FDA are a necessary and dramatic departure from the plain box warnings that have been in use for nearly 35 years. Cigarette warning labels that include atten...

Motivational interviewing for smoking cessation
Cochrane Database of Systematic Reviews;

Jul 30th, 2019 - Background Motivational Interviewing (MI) is a directive patient‐centred style of counselling, designed to help people to explore and resolve ambivalence about behaviour change. It was developed as a treatment for alcohol abuse, but may help people to a make a successful attempt to stop smoking. Objectives To evaluate the efficacy of MI for smoking cessation compared with no treatment, in ...

Incentives for smoking cessation
Cochrane Database of Systematic Reviews;

Jul 16th, 2019 - Background Financial incentives, monetary or vouchers, are widely used in an attempt to precipitate, reinforce and sustain behaviour change, including smoking cessation. They have been used in workplaces, in clinics and hospitals, and within community programmes. Objectives To determine the long‐term effect of incentives and contingency management programmes for smoking cessation. Searc...

HIV, schizophrenia, and all-cause mortality
Schizophrenia Research;

Jun 26th, 2019 - Schizophrenia is a severe mental illness with important implications for morbidity and mortality. This population-based cohort study examined the impact of schizophrenia diagnoses on all-cause mortality among a sample of people living with HIV (PLHIV) and a 10% random sample of individuals living without HIV (HIV-) in British Columbia (BC), through a data linkage between the BC Centre for Excel...

Drug Overdose Deaths | Drug Overdose | CDC Injury Center

Jun 26th, 2019 - 70,237 drug overdose deaths occurred in the United States in 2017. The age-adjusted rate of overdose deaths increased significantly by 9.6% from 2016 (19.8 per 100,000) to 2017 (21.7 per 100,000). Opioids—mainly synthetic opioids (other than methadone)—are currently the main driver of drug overdose deaths. Opioids were involved in 47,600 overdose deaths in 2017 (67.8% of all drug overdose deaths).

Building Systems to Address Tobacco Use in Oncology: Early Benefits and Opportunities From the Cancer Center Cessation Initiative
Journal of the National Comprehensive Cancer Network; Jenssen, B. et. al.

Jun 14th, 2019 - The 2014 Surgeon General’s report underscored the importance of helping patients with cancer quit smoking, because continued smoking after a diagnosis is causally linked to cancer-specific and all-cause mortality.1 More than 50% of patients with cancer who smoked before diagnosis continue to smoke after diagnosis and treatment,2 leading to calls from NCCN,3 ASCO,4 and the American Association f...

Binge Drinking and Prescription Opioid Misuse in the U.S., 2012–2014
American Journal of Preventive Medicine; Esser, M et. al.

Jun 10th, 2019 - Introduction Prescription opioids were responsible for approximately 17,000 deaths in the U.S. in 2016. One in five prescription opioid deaths also involve alcohol. Drinkers who misuse prescription opioids (i.e., use without a prescription or use only for the experience or feeling it causes) are at a heightened risk of overdose. However, little is known about the relationship between drinking ...

National Institute on Alcohol Abuse and Alcoholism - What Is A Standard Drink?

Apr 28th, 2019 - Many people are surprised to learn what counts as a drink. The amount of liquid in your glass, can, or bottle does not necessarily match up to how much alcohol is actually in your drink. Different types of beer, wine, or malt liquor can have very different amounts of alcohol content. For example, many light beers have almost as much alcohol as regular beer – about 85% as much.

National Institute on Alcohol Abuse and Alcoholism - Brochures and Fact Sheets

Apr 28th, 2019 - This section contains easy-to-read material for the public covering a wide range of alcohol-related topics. Publications listed below are online full text and free of charge unless otherwise noted.

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation
The Cochrane Database of Systematic Reviews; Lindson, N. et. al.

Apr 16th, 2019 - Background Nicotine replacement therapy (NRT) aims to replace nicotine from cigarettes to ease the transition from cigarette smoking to abstinence. It works by reducing the intensity of craving and withdrawal symptoms. Although there is clear evidence that NRT used after smoking cessation is effective, it is unclear whether higher doses, longer durations of treatment, or using NRT before cessa...

Public Policy Statement on the Ethical Use of Drug Testing in the Practice of Addiction Medicine

Apr 16th, 2019 - Drug testing uses a biological sample to detect the presence of drugs and/or drug metabolites in a patient’s body. Drug tests are ordered by physicians in a range of medical specialties, but drug testing has particular utility in addiction practices. In clinical addiction medicine, drug testing can provide the treating clinician with objective information about a patient’s recent substance u...

Maternal Smoking Before and During Pregnancy and the Risk of Sudden Unexpected Infant Death
Pediatrics Anderson, T. et. al.

Mar 10th, 2019 - OBJECTIVES: Maternal smoking during pregnancy is an established risk factor for sudden unexpected infant death (SUID). Here, we aim to investigate the effects of maternal prepregnancy smoking, reduction during pregnancy, and smoking during pregnancy on SUID rates. METHODS: We analyzed the Centers for Disease Control and Prevention Birth Cohort Linked Birth/Infant Death Data Set (2007–2011: 2...

AHNS Position Statement on Tobacco, E-cigarettes, and Marijuana

Mar 7th, 2019 - Tobacco use is the single most preventable cause of morbidity and mortality in the United States. In fact, cigarette smoking is the single largest risk factor for cancer, including head and neck cancer.

State Medical Marijuana Laws

Mar 4th, 2019 - In 1996, California voters passed Proposition 215, making the Golden State the first in the union to allow for the medical use of marijuana. Since then, 33 more states, the District of Columbia, Guam, Puerto Rico and US Virgin Islands have enacted similar laws. As of Jan. 22, 2018, the Vermont legislature passed adult-use legalization legislation and the governor signed the bill. The measure do...

Substance-Linked Sex in Heterosexual, Homosexual, and Bisexual Men and Women: An Online, Cross-Sectional “Global Drug Survey” Report
Lawn. W., et al

Mar 1st, 2019 - Introduction Substance use in sexual contexts has received recent attention, but it has mostly been restricted to men who have sex with men and the so-called “chemsex” phenomenon. Aim To explore the use of licit and illicit substances in combination with sex in heterosexual, homosexual, and bisexual men and women; to explore substance-linked sex (SLS) differences across sexual orientation ...

Relapse prevention interventions for smoking cessation
Livingstone‐Banks, Jonathan

Feb 14th, 2019 - Behavioural interventions that teach people to recognise situations that are high risk for relapse along with strategies to cope with them provided no worthwhile benefit in preventing relapse in assisted abstainers, although unexplained statistical heterogeneity means we are only moderately certain of this. In people who have successfully quit smoking using pharmacotherapy, there were mixed res...

Tobacco Use By Youth Is Rising

Feb 11th, 2019 - Tobacco product use among US youth is increasing. More than 1 in 4 high school students and about 1 in 14 middle school students in 2018 had used a tobacco product in the past 30 days. This was a considerable increase from 2017, which was driven by an increase in e-cigarette use. E-cigarette use increased from 11.7% to 20.8% among high school students and from 3.3% to 4.9% among middle school s...

A Transitioning Epidemic: How The Opioid Crisis Is Driving The Rise In Hepatitis C
Powell, D. et. al.

Feb 3rd, 2019 - The hepatitis C virus is responsible for more deaths in the United States than any other infectious disease, and hepatitis C infections have been rising at an alarming rate since 2010. We evaluated the role of the opioid epidemic and, in particular, the 2010 introduction of an abuse-deterrent version of OxyContin. The OxyContin reformulation led some users of the drug to switch to heroin, which...

Effective management of opioid withdrawal symptoms: A gateway to opioid dependence treatment
Kosten, T. et. al.

Jan 30th, 2019 - The opioid crisis has taken an immense toll in the United States. On average, five lives are lost to an opioid overdose every hour of the day; estimated costs associated with opioid misuse exceed $500 billion annually. Illicit opioid discontinuation is the first step in the treatment of opioid use disorder (OUD), and transition to an opioid agonist may initiate treatment. However, discontinuati...

E-Cigarettes and Similar Devices
Jenssen, B. et. al.

Jan 30th, 2019 - Electronic cigarettes (e-cigarettes) are the most commonly used tobacco product among youth. The 2016 US Surgeon General’s Report on e-cigarette use among youth and young adults concluded that e-cigarettes are unsafe for children and adolescents. Furthermore, strong and consistent evidence finds that children and adolescents who use e-cigarettes are significantly more likely to go on to use tra...

Challenges with Implementing the Centers for Disease Control and Prevention Opioid Guideline: A Consensus Panel Report
Kroenke, K. et. al.

Jan 24th, 2019 - A national crisis of opioid-related morbidity, mortality, and misuse has led to initiatives to address the appropriate role of opioids to treat pain. Deployment of a guideline from the Centers for Disease Control and Prevention to reduce the risks of opioid therapy has raised substantial clinical and public policy challenges. The agency anticipated implementation challenges and committed to ree...

Telehealth Services

Dec 31st, 2018 - The Substance Use-Disorder Prevention that Promotes Opioid Recovery and Treatment (SUPPORT) for Patients and Communities Act removes the originating site geographic conditions and adds an individual’s home as a permissible originating telehealth services site for treatment of a substance use disorder or a co-occurring mental health disorder.

Naloxone: The Opioid Reversal Drug that Saves Lives
U.S. Department of Health and Human Services (HSS)

Dec 18th, 2018 - The Centers for Disease Control and Prevention (CDC) reports that 70,237 Americans died from drug overdoses in 2017, of which 47,600 were opioid related. Also in 2017, 11.

2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment: A Report of the A...
Writing Committee

Dec 4th, 2018 - Tobacco use, especially cigarette smoking, is a major risk factor for cardiovascular morbidity and mortality and is the leading preventable cause of death worldwide. Comprehensive tobacco cessation treatment is a critical component of the clinical care for individuals with or at risk for cardiovascular diseases.

Opioids in Nursing Homes

Dec 3rd, 2018 - AMDA – The Society for Post-Acute and Long-Term Care Medicine has two primary policies related to opioids in nursing homes: 1. Provide access to opioids when indicated to relieve suffering and to improve or maintain function, and 2. Promote opioid tapering, discontinuation and avoidance of opioids when the above goals are not achievable, to prevent adverse events, dependence and diversion.

MORPHABOND™ ER (morphine sulfate) Prescribing Information

Nov 30th, 2018 - MORPHABOND ER is an opioid agonist indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

ROXYBOND (oxycodone hydrochloride) Prescribing Information

Nov 30th, 2018 - ROXYBOND is an opioid agonist indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Three New State Laws Legalize Marijuana Use, Sparking More Confusion and Igniting Further Conflict With Federal Law

Nov 20th, 2018 - The mid-term elections are still on people’s minds, as recounts and run-offs for federal congressional and state gubernatorial candidates are finally wrapping up. Meanwhile, and largely taking a media-coverage backseat to these high-profile races, many new state initiatives became law as a result of the mid-terms, three which involved legalizing marijuana for recreational or medical use. Thes...

Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interve...
U.S. Preventative Services Task Force (USPSTF)

Nov 12th, 2018 - The USPSTF recommends screening for unhealthy alcohol use in primary care settings in adults 18 years or older, including pregnant women, and providing persons engaged in risky or hazardous drinking with brief behavioral counseling interventions to reduce unhealthy alcohol use. Keywords: alcoholism, addiction, alcohol, alcohol abuse, alcohol use disorder.

CDC OPIOID GUIDELINE: Implementation Guide for Electronic Health Records
Opioid Crisis Task Force

Oct 31st, 2018 - The Electronic Health Record Association (EHRA) is committed to bringing leaders from our EHR developer community together to collaborate on solving industry challenges. In 2018, the Association’s Opioid Crisis Task Force was formed to research and provide recommendations on ways EHR technology can help with solving the complex puzzle of the opioid crisis.

ANA Position Statement: The Ethical Responsibility to Manage Pain and the Suffering It Causes

Oct 28th, 2018 - The purpose of this position statement is to provide ethical guidance and support to nurses as they fulfill their responsibility to provide optimal care to persons experiencing pain. The national debate on the appropriate use of opioids highlights the complexities of providing optimal management of pain and the suffering it causes.

Cannabis Position Statement
Canadian Lung Association

Oct 16th, 2018 - The Canadian Lung Association aspires to a future free of lung disease. Prevention is imperative in making this future possible.

Interaction between warfarin and cannabis
Damkier, P. et. al.

Oct 15th, 2018 - Delta‐9‐tetrahydrocannabinol (THC), the main psychoactive cannabinoid in cannabis, may inhibit the cytochrome P450 enzyme CYP2C9. Consequently, cannabis use might infer a risk of drug‐drug interaction with substrates for this enzyme, which includes drugs known to have a narrow therapeutic window. In this study, we describe a case report of a 27‐year‐old man treated with warfarin due to mechanic...

American Gastroenterological Association Institute Guideline on the Medical Management of Op...

Oct 15th, 2018 - This document presents the official recommendations of the American Gastroenterological Association (AGA) on the medical management of opioid-induced constipation. The guideline was developed by the AGA Institute’s Clinical Guidelines Committee and approved by the AGA Governing Board.

American Gastroenterological Association Institute Technical Review on the Medical Managemen...
Hanson, B.

Oct 15th, 2018 - Opioid medications are some of the most commonly prescribed medications for acute and chronic pain in the United States. In 2016, nearly 92 million US adults, or approximately 38% of the population, were prescribed opioids, according to results from the National Survey on Drug Use and Health.

Recommendations for the Appropriate Structure, Communication, and Investigation of Tobacco H...
Leone, F.

Oct 14th, 2018 - The tobacco harm reduction literature is replete with vague language, far-reaching claims, and unwarranted certainty. The American Thoracic Society has increasingly recognized the need for a framework for reliably making such claims.

Opioid-Prescribing Guidelines for Common Surgical Procedures: An Expert Panel Consensus
Overton, H.

Sep 30th, 2018 - One in 16 surgical patients prescribed opioids becomes a long-term user. Overprescribing opioids after surgery is common, and the lack of multidisciplinary procedure-specific guidelines contributes to the wide variation in opioid prescribing practices.

Alcohol and Cancer Risk

Sep 12th, 2018 - Alcohol is the common term for ethanol or ethyl alcohol, a chemical substance found in alcoholic beverages such as beer, hard cider, malt liquor, wines, and distilled spirits (liquor). Alcohol is produced by the fermentation of sugars and starches by yeast. Alcohol is also found in some medicines, mouthwashes, and household products (including vanilla extract and other flavorings). This fact sh...

Marijuana Use by Breastfeeding Mothers and Cannabinoid Concentrations in Breast Milk
Bertrand, K. et. al.

Aug 31st, 2018 - Marijuana is the most commonly used recreational drug among breastfeeding women. With legalization of marijuana in several US states and a 1990 study in which authors documented psychomotor deficits in infants breastfed by mothers using marijuana, there is a need for information on potential exposure to the breastfed infant. Our objective with this study was to quantify cannabinoids in human m...

Marijuana Use During Pregnancy and Breastfeeding: Implications for Neonatal and Childhood Ou...
Ryan, S.

Aug 31st, 2018 - Marijuana is one of the most widely used substances during pregnancy in the United States. Emerging data on the ability of cannabinoids to cross the placenta and affect the development of the fetus raise concerns about both pregnancy outcomes and long-term consequences for the infant or child.

Inclusion of Addiction Specialist Physicians in Managed Behavioral Health Care Organization ...
American Society of Addiction Medicine

Jul 24th, 2018 - Patients presenting with substance-related and addictive disorders often face barriers to obtaining successful treatment due to the stigma associated with the disease, insufficient access to high quality care including skilled clinicians, and gaps in the continuum of treatment available to treat their disorders. Patients who do avail themselves of treatment often access these services through m.

MORPHABOND ER Medication Guide

May 31st, 2018 - MORPHABOND ER is: A strong prescription pain medicine that contains an opioid (narcotic) that is used to manage pain severe enough to require daily around-the clock, long-term treatment with an opioid, when other pain treatments such as non-opioid pain medicines or immediate-release opioid medicines do not treat your pain well enough or you cannot tolerate them.

Guideline for Discharge Opioid Prescriptions after Inpatient General Surgical Procedures
Hill, Maureen

May 31st, 2018 - There is a paucity of data to inform appropriate opioid prescribing for patients who are discharged after a hospital admission for a surgical procedure. We studied 333 inpatients discharged to home after bariatric, benign foregut, liver, pancreas, ventral hernia, and colon surgery.

Public Policy Statement on Ethical Promotion and Patient Recruitment by Addiction Treatment ...
American Society of Addiction Medicine (ASAM)

May 24th, 2018 - ASAM recognizes that individuals with addiction as well as their families and others who assist them to access treatment are vulnerable and at high risk for exploitation, particularly at times of crisis when treatment is sought. As such, treatment programs should be held to the highest standard of ethical practice in the marketing of their services and recruitment of patients.

Joint Public Correctional Policy Statement on the Treatment of Opioid Use Disorders for Just...
American Society of Addiction Medicine (ASAM)

May 11th, 2018 - The American Correctional Association (ACA) supports the use of evidence-based practices for the treatment of opioid use disorders. ACA and the American Society of Addiction Medicine (ASAM) have developed recommendations specific to the needs of correctional policy makers and healthcare professionals.

Risk Factors for Opioid Use Disorders in Adult Postsurgical Patients
Burcher, K. et. al.

May 10th, 2018 - The use of opioids in the treatment of chronic pain is one of the most controversial topics in medicine today. Many studies have proposed that the postoperative period is a vulnerable time for patients at risk for developing an opioid use disorder. Many patients are prescribed opioids for management of their postsurgical pain and continue using them for prolonged amounts of time following their...

Fentanyl and Other Synthetic Opioids Drug Overdose Deaths

Apr 30th, 2018 - In 2016, synthetic opioids (primarily illegal fentanyl) passed prescription opioids as the most common drugs involved in overdose deaths in the United States.

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder
Yatham, L. et. al.

Apr 20th, 2018 - The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously pub-lished treatment guidelines for bipolar disorder in 2005, along with international com-mentaries and subsequent updates in 2007, 2009, and 2013. The last two updates were published in collaboration with the International Society for Bipolar Disorders (ISBD). These 2018 CANMAT and ISBD Bipolar Treatment Guidelines repre...

Statement on Opioid Use in Patients with Hematologic Diseases and Disorders
American Society of Hematology

Apr 17th, 2018 - According to the Centers for Disease Control and Prevention, overdoses from prescription opioids in the United States have contributed to the 15-year increase in opioid overdose deaths and nearly half of all opioid overdose deaths involve a prescription opioid. The Society is alarmed about the opioid crisis, however, it is concerned about potential adverse effects that policy changes could have.

What Is the Evidence for “Food Addiction?” A Systematic Review
Nutrients Gordon, E. et. al.

Apr 11th, 2018 - The diagnostic construct of “food addiction” is a highly controversial subject. The current systematic review is the first to evaluate empirical studies examining the construct of “food addiction” in humans and animals. Studies were included if they were quantitative, peer-reviewed, and in the English language. The 52 identified studies (35 articles) were qualitatively assessed to determine the...

Prescription Drug Monitoring Programs (PDMPs)
American Society of Addiction Medicine (ASAM)

Apr 10th, 2018 - Prescription Drug Monitoring Programs (PDMPs) are statewide electronic databases that collect designated data from pharmacies and medical offices that dispense controlled substances in the state. PDMPs are maintained at the state level and housed in various statewide regulatory, administrative, or law enforcement agencies.

The Role of Recovery in Addiction Care
American Society of Addiction Medicine (ASAM)

Apr 10th, 2018 - ASAM recognizes addiction as a primary chronic disease of the brain. People with the disease of addiction have debilitating signs and symptoms that affect their mental and social well-being, disrupt insight, and degrade their physical health.

Enforcing Federal Drug Laws in States Where Medical Marijuana Is Lawful

Apr 9th, 2018 - On January 4, 2018, Attorney General Jeff Sessions issuedamemorandum immediately rescinding theObama Administration’s long-standing guidance limiting federal enforcement ofmedicalmarijuana.1 Federal law creates harsh penalties for the cultivation, distribution, and possession ofmarijuana, whichSessions deemed a “dangerous drug” and a “serious crime.” The memorandum places physicians and pat...

Alcohol Advertising
American College of Emergency Physicians

Mar 31st, 2018 - The American College of Emergency Physicians (ACEP) strongly opposes advertisements of alcoholic beverages, particularly those that are aimed at young audiences who may be especially susceptible to the advertising, those that are aired during sporting events, and those which draw a positive correlation between physical performance and the consumption of alcoholic beverages.

Improving the Safety of Opioid Use for Acute Noncancer Pain in Hospitalized Adults:A Consens...

Mar 31st, 2018 - Hospital-based clinicians frequently treat acute, noncancerpain. Although opioids may be beneficial in this setting,the benefits must be balanced with the risks of adverseevents, including inadvertent overdose and prolongedopioid use, physical dependence, or development ofopioid use disorder.

Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
International Journal of Molecular Sciences;

Mar 12th, 2018 - The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled receptor family, cannabinoid receptors 1 (CB1R) and 2. The CB1R is the prominent subtype in the central nervous system (CNS) and has drawn great attention as a potential therapeutic avenue in several pathological condition...

Management of opioid use disorders: a national clinical practice guideline
Julie Bruneau

Mar 4th, 2018 - Opioid use disorder is often a chronic, relapsing condition associated with increased morbidity and death, however, with appropriate treatment and follow-up, individuals can reach sustained long-term remission. This guideline strongly recommends opioid agonist treatment with buprenorphine–naloxone as the preferred first-line treatment when possible, because of buprenorphine’s multiple advantages.

Malley, G. et. al.

Mar 1st, 2018 - Amphetamines are sympathomimetic drugs with CNS stimulant and euphoriant properties whose toxic adverse effects include delirium, hypertension, seizures, and hyperthermia (which can cause rhabdomyolysis and renal failure). Toxicity is managed with supportive care, including IV benzodiazepines (for agitation, hypertension, and seizures) and cooling techniques (for hyperthermia). There is no ster...

APS OpioId Treatment Guidelines. Clinical Guidelines for the Use of Chronic Opioid Therapy i...
Roger Chou

Jan 31st, 2018 - Use of chronic opioid therapy for chronic noncancer pain has increased substantially. The American Pain Society and the American Academy of Pain Medicine commissioned a systematic review of the evidence on chronic opioid therapy for chronic noncancer pain and convened a multidisciplinary expert panel to review the evidence and formulate recommendations.

Lifestyle Management: Standards of Medical Care in Diabetes—2018 - ADA Guideline
American Diabetes Association

Jan 30th, 2018 - Lifestyle management is a fundamental aspect of diabetes care and includes diabetes self-management education and support (DSMES), medical nutrition therapy (MNT), physical activity, smoking cessation counseling, and psychosocial care. Patients and care providers should focus together on how to optimize lifestyle from the time of the initial comprehensive medical evaluation, throughout all subs.

Binge Drinking: Predictors, Patterns, and Consequences
Alcohol Research; White, A. et. al.

Jan 1st, 2018 - he National Institute on Alcohol Abuse and Alcoholism defines binge drinking as a pattern of consumption that causes blood alcohol concentration to rise to .08%—the legal limit for adults ages 21 or older operating a motor vehicle—or more. This level typically occurs after a woman consumes four drinks or a man consumes five drinks—in about 2 hours. Research suggests that three out of four adole...

Pharmacological Treatment of Patients with Alcohol Use Disorder
Victor I. Reus

Dec 31st, 2017 - The goal of this guideline is to improve the quality of care and treatment outcomes for patients with alcohol use disorder (AUD), as defined by DSM-5 (American Psychiatric Association 2013). The guideline focuses specifically on evidence-based pharmacological treatments for AUD but also includes statements related to assessment and treatment planning that are an integral part of using pharmacot.

Rational Urine Drug Monitoring in Patients Receiving Opioids for Chronic Pain: Consensus Rec...
Argoff, C.,et al

Dec 31st, 2017 - Objective: To develop consensus recommendations on urine drug monitoring (UDM) in patients with chronic pain who are prescribed opioids. Methods: An interdisciplinary group of clinicians with expertise in pain, substance use disorders, and primary care conducted virtual meetings to review relevant literature and existing guidelines and share their clinical experience in UDM before reaching cons.

Alcohol and Cancer: A Statement of the American Society of Clinical Oncology
LoConte, N.,et al

Nov 6th, 2017 - Alcohol drinking is an established risk factor for several malignancies, and it is a potentially modifiable risk factor for cancer. The Cancer Prevention Committee of the American Society of Clinical Oncology (ASCO) believes that a proactive stance by the Society to minimize excessive exposure to alcohol has important implications for cancer prevention.

News - Inspirion Delivery Sciences

Nov 4th, 2017 - Recent News About Inspirion Delivery Sciences, a subsidiary of Inspirion Delivery Technologies. View MorphaBond™ ER Full Prescribing Information. View RoxyBond™ Full Prescribing Information

Stakeholder Research Priorities for Smoking Cessation Interventions within Lung Cancer Scree...
Hasmeena Kathuria

Oct 31st, 2017 - There was little consensus on which questions within the population domain were of highest priority. Within the intervention domain, research to evaluate the effectiveness in the lung cancer screening setting of evidence-based smoking cessation interventions shown to be effective in other contexts was ranked highest.

WMA Statement on Medical Cannabis
World Medical Association

Sep 30th, 2017 - In considering policy and legislation on cannabis, governments, NMAs, policymakers, and other health stakeholders, should emphasize and examine the health effects and therapeutic benefits based on the available evidence, while also recognizing various contextual factors such as regulatory capacity, cost-effectiveness, societal values, social circumstances of the country, and the public health a.

Opioids in Gastroenterology: Treating Adverse Effects and Creating Therapeutic Benefits
Michael Camilleri, Anthony Lembo et. al.

Sep 29th, 2017 - The use of opioid medications on both an acute and chronic basis is ubiquitous in the United States. As opioid receptors densely populate the gastrointestinal tract, symptoms and side effects can be expected in these patients.

2017 HIVMA of IDSA Clinical Practice Guideline for the Management of Chronic Pain in Patient...
R Douglas Bruce

Sep 13th, 2017 - Pain has always been an important part of human immunodeficiency virus (HIV) disease and its experience for patients. In this guideline, we review the types of chronic pain commonly seen among persons living with HIV (PLWH) and review the limited evidence base for treatment of chronic noncancer pain in this population.

Position Statement 16: Addressing the Health- Related Social Needs of People with Mental Hea...
National Mental Health America

Sep 8th, 2017 - Mental Health America (MHA) calls for dedication of significant state and federal resources to reduce the alarmingly high rates of overall health problems (morbidity) and premature death (mortality) among people with serious mental illnesses, – which must include an array of strategies for addressing health-related social needs. With the addition of effective surveillance and treatment services.

Public Policy Statement on Ethical Promotion of Addiction Treatment Medications: ASAM Guideline
American Society of Addiction Medicine

Sep 8th, 2017 - Significant and rapid progress has been made in both the scientific understanding of the disease of addiction and the medical interventions available to treat it. There has been especially notable expansion in the number of prescription pharmacotherapies available to treat patients with addiction, with the pharmaceutical arsenal of addiction medicine physicians nearly doubling since 2000.

ACMT and AACT position statement: preventing occupational fentanyl and fentanyl analog expos...
Michael J. Moss

Aug 23rd, 2017 - Fentanyl and its analogs are potent opioid receptor agonists, but the risk of clinically significant exposure to emergency responders is extremely low. To date, we have not seen reports of emergency responders developing signs or symptoms consistent with opioid toxicity from incidental contact with opioids.

The general surgeon’s role in enhancing patient education about prescription opioids: ACS Gu...

Aug 1st, 2017 - Understanding the patient population within the surgeon’s geographic practice area is important to determine which patients may potentially seek increased opioid prescriptions versus those who choose not to use narcotic pain management due to social, spiritual, or religious beliefs.

Academic Medicine's Response to the Opioid Epidemic
Association of American Medical Colleges (AAMC)

Jun 30th, 2017 - Opioid dependence has devastated communities across the country, and a collective effort across multiple sectors is needed to stem the tide of opioid misuse and substance abuse. Through their missions of education, research, and clinical care, medical schools and teaching hospitals are actively responding to this public health crisis and preparing the next generation of health care professional.

Daiichi Sankyo, Inc. and Inspirion Delivery Sciences LLC Announce Plans for Commercialization of RoxyBond™ (oxycodone hydrochloride) Tablets CII in the U.S.

May 30th, 2017 - Daiichi Sankyo, Inc. and Inspirion Delivery Sciences LLC (Inspirion) announced today that Daiichi Sankyo will lead the U.S. commercialization of FDA-approved RoxyBond™ (oxycodone hydrochloride) immediate-release tablets, for oral use, CII with Inspirion providing additional salesforce as part of Inspirion’s co-promotion rights under the License Agreement. RoxyBond is indicated for the managemen...

Hepatitis C Infection: ASAM Guideline
American Society of Addiction Medicine

Apr 4th, 2017 - HCV is primarily transmitted through percutaneous exposure to contaminated blood. Since 1992, the US blood supply has been screened for Hepatitis C, making the risk of transfusion-transmitted HCV extremely rare.

ROXYBOND (oxycodone hydrochloride) Medication Guide

Mar 31st, 2017 - ROXYBOND is: A strong prescription pain medicine that contains an opioid (narcotic) that is used to manage pain severe enough to require an opioid pain medicine, when other pain treatments such as nonopioid pain medicines do not treat your pain well enough or you cannot tolerate them.

Opioid-Induced Bowel Dysfunction
Ketwaroo, G. et. al.

Feb 7th, 2017 - Opioid-induced bowel dysfunction (OIBD) is a potentially debilitating side effect of chronic opioid use. It refers to a collection of primarily gastrointestinal motility disorders induced by opioids, of which opioid-induced constipation (OIC) is the most common. Management of OIBD is difficult, and affected patients will often limit their opioid intake at the expense of experiencing more pain, ...

Treating the Rural Opioid Epidemic
Christine Hancock

Jan 31st, 2017 - Abuse of prescription and illicit opioids has become at top priority public health issue in the past decade, and its effects on rural communities cannot be understated. Effective, evidence-based treatment of opioid use disorders is urgently needed in small towns across America.

Substance Use, Misuse, and Use Disorders During and Following Pregnancy, with an Emphasis on...
American Society of Addiction Medicine

Jan 17th, 2017 - The American Society of Addiction Medicine (ASAM) is deeply committed to the health and well-being of mothers and children. This includes advocating for prevention and treatment of substance-related harm throughout a woman's reproductive years, with a particular focus on addiction and substance use during and following pregnancy.

Alcohol Screening in the Emergency Department: ACEP Guideline
American College of Emergency Physicians

Dec 31st, 2016 - The American College of Emergency Physicians (ACEP) believes alcohol abuse is a significant public health problem. Further, ACEP believes emergency medical professionals are positioned and qualified to mitigate the consequences of alcohol abuse through screening programs, brief intervention, and referral to treatment.

Opioid Prescribing: Acute and Postoperative Pain Management
American Association of Oral and Maxillofacial Surgeons (AAOMS)

Dec 31st, 2016 - Oral and maxillofacial surgeons must demonstrate safe and competent opioid prescribing for acute and postoperative pain in their patients. Responsible prescribing of opioids must be a priority, including accessing the state’s prescription-drug monitoring program as well as educating the patient and family about potential risks – and the safe use, storage and disposal – of opioid analgesics.

Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology
Shields, P.,et al

Oct 31st, 2016 - Cigarette smoking has been implicated in causing many cancers and cancer deaths. There is mounting evidence indicating that smoking negatively impacts cancer treatment efficacy and overall survival.

Use of Naloxone for the Prevention of Opioid Overdose Deaths: ASAM Guideline
American Society of Addiction Medicine

Oct 7th, 2016 - Naloxone is a mu-opioid antagonist with well-established safety and efficacy that can reverse opioid overdose and prevent fatalities. Naloxone treatment of opioid overdose has been in use in hospital settings for decades.

Chronic postsurgical pain and persistent opioid use following surgery: the need for a transitional pain service
Huang, A. et. al.

Jul 5th, 2016 - Aim: To identify the 3-month incidence of chronic postsurgical pain and long-term opioid use in patients at the Toronto General Hospital. Methods: 200 consecutive patients presenting for elective major surgery completed standardized questionnaires by telephone at 3 months after surgery. Results: 51 patients reported a preoperative chronic pain condition, with 12 taking opioids preoperatively. 3...

Methadone for Pain Management: Improving Clinical Decision Making

Jun 30th, 2016 - Patients with intermittent chronic pain requiring opioid medication only "as needed" or who have a history of medication non-compliance are not good candidates for methadone therapy.

3 steps for talking with patients about substance use disorder

May 22nd, 2016 - When a patient with a substance use disorder comes in for a visit, talking to them about treating their addiction in a way that avoids the stigma that surrounds these disorders can be difficult. Learn how one physician approaches this conversation during her addiction consultations with patients.

For a Healthier U.S.: Methods to Fight Prescription Abuse
Pharmaceutical Research and Manufacturers of America (PhRMA)

May 4th, 2016 - Given the growing toll related to the abuse of prescription opioids and heroin, we must collectively redouble our efforts to prevent the misuse, abuse and diversion of prescription medicines. We need a balanced approach that ensures appropriate access and use of prescription medicines by patients for legitimate medical needs under the direction and care of a licensed health care professional, b.