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About 1,925 results

ALLMedicine Hypogammaglobulinemia Center

Research & Reviews  929 results

Identifying Novel Mutations in Iranian Patients with LPS-responsive Beige-like Anchor P...
https://doi.org/10.1080/08820139.2020.1770784
Immunological Investigations; Ghaini M, Arzanian MT et. al.

May 31st, 2020 - LPS-responsive beige-like anchor protein (LRBA) deficiency is a monogenic primary immunodeficiency characterized by a heterogeneous spectrum of clinical manifestations associated with immune dysregulation. In this study, we reported clinical, immu...

Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-Analysis.
https://doi.org/10.1016/j.chest.2020.04.058
Chest Leitao Filho FS, Mattman A et. al.

May 17th, 2020 - Hypogammaglobulinemia (serum immunoglobulin G (IgG) levels < 7.0 g/L) has been associated with increased risk of COPD exacerbations but has not yet been shown to predict hospitalizations. To determine the relationship between hypogammaglobulinemia...

Genetic Studies of Chronic Active Epstein-Barr Disease
https://clinicaltrials.gov/ct2/show/NCT00032513

May 7th, 2020 - Patients with chronic active Epstein-Barr virus (CAEBV) have (a) an illness that began as a primary infection with EBV or markedly elevated titers of antibodies to EBV, (b) histological evidence of organ disease, and (c) elevated EBV DNA levels in...

Hypogammaglobulinemia and Risk of Exacerbation and Mortality in Patients with COPD.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173948
International Journal of Chronic Obstructive Pulmonary Disease; Holm AM, Andreassen SL et. al.

May 5th, 2020 - Chronic obstructive pulmonary disease (COPD) may, in some patients, be characterized by recurring acute exacerbations. Often these exacerbations are associated with airway infections. As immunoglobulins (Ig) are important parts of the immune defen...

Imatinib-Induced Hypogammaglobulinemia in Children and Adolescents with Chronic Myeloid...
https://doi.org/10.1080/08880018.2020.1759739
Pediatric Hematology and Oncology; Totadri S, Thipparapu S et. al.

May 4th, 2020 - Imatinib-induced tyrosine kinase inhibition extends beyond the BCR-ABL mutation, resulting in adverse effects. We evaluated hypogammaglobulinemia as a potential 'off-target' action of imatinib in children with CML. A cross-sectional, observational...

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Drugs  4 results see all →

Clinicaltrials.gov  959 results

Identifying Novel Mutations in Iranian Patients with LPS-responsive Beige-like Anchor P...
https://doi.org/10.1080/08820139.2020.1770784
Immunological Investigations; Ghaini M, Arzanian MT et. al.

May 31st, 2020 - LPS-responsive beige-like anchor protein (LRBA) deficiency is a monogenic primary immunodeficiency characterized by a heterogeneous spectrum of clinical manifestations associated with immune dysregulation. In this study, we reported clinical, immu...

Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-Analysis.
https://doi.org/10.1016/j.chest.2020.04.058
Chest Leitao Filho FS, Mattman A et. al.

May 17th, 2020 - Hypogammaglobulinemia (serum immunoglobulin G (IgG) levels < 7.0 g/L) has been associated with increased risk of COPD exacerbations but has not yet been shown to predict hospitalizations. To determine the relationship between hypogammaglobulinemia...

Genetic Studies of Chronic Active Epstein-Barr Disease
https://clinicaltrials.gov/ct2/show/NCT00032513

May 7th, 2020 - Patients with chronic active Epstein-Barr virus (CAEBV) have (a) an illness that began as a primary infection with EBV or markedly elevated titers of antibodies to EBV, (b) histological evidence of organ disease, and (c) elevated EBV DNA levels in...

Hypogammaglobulinemia and Risk of Exacerbation and Mortality in Patients with COPD.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173948
International Journal of Chronic Obstructive Pulmonary Disease; Holm AM, Andreassen SL et. al.

May 5th, 2020 - Chronic obstructive pulmonary disease (COPD) may, in some patients, be characterized by recurring acute exacerbations. Often these exacerbations are associated with airway infections. As immunoglobulins (Ig) are important parts of the immune defen...

Imatinib-Induced Hypogammaglobulinemia in Children and Adolescents with Chronic Myeloid...
https://doi.org/10.1080/08880018.2020.1759739
Pediatric Hematology and Oncology; Totadri S, Thipparapu S et. al.

May 4th, 2020 - Imatinib-induced tyrosine kinase inhibition extends beyond the BCR-ABL mutation, resulting in adverse effects. We evaluated hypogammaglobulinemia as a potential 'off-target' action of imatinib in children with CML. A cross-sectional, observational...

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News  33 results

Cautionary Findings on Acquired Immunodeficiency From Anti-CD20 MS Therapy
https://www.medscape.com/viewarticle/929997

May 4th, 2020 - REPORTING FROM AAN 2020 Thirty-eight percent of a large cohort of multiple sclerosis (MS) patients developed low IgM and 7.4% became hypogammaglobulinemic during a mean 30 months of follow-up on anti-CD20 therapy, Brandi L. Vollmer, MPH, reported ...

Hypogammaglobulinemia and infection risk clarified in MS patients on anti-CD20 agents
https://www.mdedge.com/multiplesclerosishub/article/209320/multiple-sclerosis/hypogammaglobulinemia-and-infection-risk/page/0/1

Oct 2nd, 2019 - Ocrelizumab Tobias Derfuss, MD, provided data on infection rates in the pivotal phase 3 OPERA and ORATIO double-blind clinical trials combined with their long-term, open-label extensions totaling 288 weeks, or nearly 6 years, of follow-up. Serum I.

Plerixafor produced dramatic responses in severe WHIM syndrome
https://www.mdedge.com/familymedicine/article/192393/anemia/plerixafor-produced-dramatic-responses-severe-whim-syndrome
MDedge Hematology and Oncology; Amy Karon

Jan 9th, 2019 - Low-dose treatment with plerixafor, a CXC chemokine receptor 4 antagonist, was well tolerated and markedly improved severe presentations of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome in three patients who could not.

Long-term side effects of CAR T cells mostly mild
https://www.mdedge.com/hematology-oncology/article/192072/cellular-therapy/long-term-side-effects-car-t-cells-mostly-mild
Neil Osterweil

Jan 4th, 2019 - SAN DIEGO – Longer-term follow-up of patients treated with CD19-targeted chimeric antigen receptor (CAR) T cells for hematologic malignancies indicates that the altered cells are generally safe, with most late events being mild in nature and possi.

Hypogammaglobulinemia Screening Needed for Patients Receiving Rituximab
https://www.medscape.com/viewarticle/904454

Nov 7th, 2018 - NEW YORK (Reuters Health) - Patients being considered for rituximab therapy should be screened for hypogammaglobulinemia before and after rituximab administration, researchers report. Several reports have described prolonged hypogammaglobulinemia ...

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