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About 1,056 results

ALLMedicine™ Nerve Agents Center

Research & Reviews  507 results

Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History,...
https://doi.org/10.1016/j.neuropharm.2020.108298
Neuropharmacology Aroniadou-Anderjaska V, Apland JP et. al.

Sep 8th, 2020 - Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to nerve agents can cause rapid death. In this review, we summarize the history of nerve agent development and use in warfare, the mechanisms by which these agents c...

Structural elucidation of V-type nerve agents by liquid chromatography/electrospray ion...
https://doi.org/10.1002/jms.4617
Journal of Mass Spectrometry : JMS REFERENCES; Shamai Yamin T, Prihed H et. al.

Jul 28th, 2020 - V-nerve agents present information-poor spectra, both in GC-EI-MS and LC-ESI-MS/MS, with dominant fragments/product ions corresponding to the amine-containing residue. Hence, derivatives/isomers with the same amine residue exhibit similar mass spe...

Discovery of treatment for nerve agents targeting a new metabolic pathway.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415758
Archives of Toxicology; Glaros T, Dhummakupt ES et. al.

Jul 28th, 2020 - The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous reports suggesting that metabolic processes could significantly contribute to toxicity. As ...

Enantioselective in-vitro elimination kinetics of nerve agents in blood monitored by de...
https://doi.org/10.1007/s00204-020-02854-8
Archives of Toxicology; Loewenthal D, Weissberg A et. al.

Jul 26th, 2020 - We present a simple method for chiral separation and analysis of organophosphorus nerve agents and apply it to monitor the enantioselective blood elimination kinetics of sarin in-vitro. The method is implemented in standard reverse phase LC-MS ope...

Magnetic resonance imaging analysis of long-term neuropathology after exposure to the n...
https://doi.org/10.1111/nyas.14431
Annals of the New York Academy of Sciences References; Reddy SD, Wu X et. al.

Jul 16th, 2020 - Nerve agents (NAs) produce acute and long-term brain injury and dysfunction, as evident from the Japan and Syria incidents. Magnetic resonance imaging (MRI) is a versatile technique to examine such chronic anatomical, functional, and neuronal dama...

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Guidelines  1 results

Responding to nerve agent poisoning: a guide for emergency nurses. Part 2.
https://doi.org/10.7748/en.2019.e1925
Emergency Nurse : the Journal of the RCN Accident and Emergency Nursing Association; McGhee S, Finnegan A et. al.

Aug 30th, 2019 - The release of chemical agents can cause loss of life and result in major incidents. Chemical agent-related major incidents require a modified response by emergency services due to the chemicals' transmissibility, lethality, latency and persistenc...

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Drugs  9 results see all →

Clinicaltrials.gov  531 results

Acetylcholinesterase inhibitors (nerve agents) as weapons of mass destruction: History,...
https://doi.org/10.1016/j.neuropharm.2020.108298
Neuropharmacology Aroniadou-Anderjaska V, Apland JP et. al.

Sep 8th, 2020 - Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to nerve agents can cause rapid death. In this review, we summarize the history of nerve agent development and use in warfare, the mechanisms by which these agents c...

Structural elucidation of V-type nerve agents by liquid chromatography/electrospray ion...
https://doi.org/10.1002/jms.4617
Journal of Mass Spectrometry : JMS REFERENCES; Shamai Yamin T, Prihed H et. al.

Jul 28th, 2020 - V-nerve agents present information-poor spectra, both in GC-EI-MS and LC-ESI-MS/MS, with dominant fragments/product ions corresponding to the amine-containing residue. Hence, derivatives/isomers with the same amine residue exhibit similar mass spe...

Discovery of treatment for nerve agents targeting a new metabolic pathway.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415758
Archives of Toxicology; Glaros T, Dhummakupt ES et. al.

Jul 28th, 2020 - The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous reports suggesting that metabolic processes could significantly contribute to toxicity. As ...

Enantioselective in-vitro elimination kinetics of nerve agents in blood monitored by de...
https://doi.org/10.1007/s00204-020-02854-8
Archives of Toxicology; Loewenthal D, Weissberg A et. al.

Jul 26th, 2020 - We present a simple method for chiral separation and analysis of organophosphorus nerve agents and apply it to monitor the enantioselective blood elimination kinetics of sarin in-vitro. The method is implemented in standard reverse phase LC-MS ope...

Magnetic resonance imaging analysis of long-term neuropathology after exposure to the n...
https://doi.org/10.1111/nyas.14431
Annals of the New York Academy of Sciences References; Reddy SD, Wu X et. al.

Jul 16th, 2020 - Nerve agents (NAs) produce acute and long-term brain injury and dysfunction, as evident from the Japan and Syria incidents. Magnetic resonance imaging (MRI) is a versatile technique to examine such chronic anatomical, functional, and neuronal dama...

see more →

News  7 results

Healthcare providers should be ready for nerve agent attacks, experts say
https://www.reuters.com/article/us-health-emergencies-nerve-agents/healthcare-providers-should-be-ready-for-nerve-agent-attacks-experts-say-idUSKCN1OJ2PI

Dec 20th, 2018 - (Reuters Health) - - Recent attacks in the UK and elsewhere using powerful nerve agents show that U.S. healthcare providers don’t need to be near a battlefield to find themselves dealing with similar emergencies, researchers argue in a commentary ...

Gulf War illness linked to chemical exposure
https://www.reuters.com/article/us-gulfwar-chemicals/gulf-war-illness-linked-to-chemical-exposure-idUSN1059348220080311

Mar 10th, 2008 - CHICAGO (Reuters) - Exposure to pesticides, nerve agents and other chemicals may explain the chronic, multi-symptom health problems experienced by up to one-third of Gulf War veterans, U.S. researchers said on Monday. A U.S. soldier stands guard a...

Gulf War illness linked to chemical exposure
https://www.reuters.com/article/us-gulfwar-chemicals/gulf-war-illness-linked-to-chemical-exposure-idUSN1059348220080310

Mar 10th, 2008 - CHICAGO (Reuters) - Exposure to pesticides, nerve agents and other chemicals may explain the chronic, multi-symptom health problems experienced by up to one-third of Gulf War veterans, U.S. researchers said on Monday. They said an analysis of a ho...

Pediatric Approval of Chemical and Pesticide Poison Antidote
https://www.mdedge.com/content/pediatric-approval-chemical-and-pesticide-poison-antidote
Elizabeth Mechcatie

A drug that has been used to treat nerve gas and other types of pesticide and chemical poisoning in children off-label for years is now approved for pediatric use, the Food and Drug Administration announced on Sept. 9.

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Patient Education  1 results see all →