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About 1,023 results

ALLMedicine Nerve Agents Center

Research & Reviews  487 results

Acetylcholinesterase inhibition resulting from exposure to inhaled OP can be prevented ...
https://doi.org/10.1016/j.neuropharm.2020.108150
Neuropharmacology Rosenberg Y, Saxena A

May 22nd, 2020 - More frequent and widespread nerve agent attacks highlight the need for efficacious pre- and post-exposure organophosphate (OP) counter-measures to protect military and civilian populations. Because of critical targeting of acetylcholinesterase (A...

Efficient detoxification of nerve agents by oxime-assisted reactivation of acetylcholin...
https://doi.org/10.1016/j.neuropharm.2020.108111
Neuropharmacology Kovarik Z, Maček Hrvat N

Apr 25th, 2020 - The recent advancements in crystallography and kinetics studies involving reactivation mechanism of acetylcholinesterase (AChE) inhibited by nerve agents have enabled a new paradigm in the search for potent medical countermeasures in case of nerve...

Impairment of wound healing by reactive skin decontamination lotion (RSDL®) in a Göttin...
https://doi.org/10.1080/15569527.2020.1751183
Cutaneous and Ocular Toxicology; Connolly JM, Stevenson RS et. al.

Apr 23rd, 2020 - Reactive Skin Decontamination Lotion (RSDL®) is an FDA-approved skin decontamination kit carried by service members for removal and neutralisation of vesicants and nerve agents. The RSDL kit, comprised of a lotion-impregnated sponge, was shown to ...

Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surr...
https://doi.org/10.1111/nyas.14352
Annals of the New York Academy of Sciences References; Chambers JE, Meek EC

Apr 20th, 2020 - Oximes remain a long-standing element of the therapy for nerve agents, organophosphates (OPs) that poison by inhibiting the enzyme acetylcholinesterase (AChE), resulting in hypercholinergic activity both centrally and peripherally. Oximes, such as...

Molecular dynamics simulation of the electron ionization mass spectrum of tabun.
https://doi.org/10.1002/jms.4513
Journal of Mass Spectrometry : JMS REFERENCES; Chernicharo FCS, Modesto-Costa L et. al.

Mar 26th, 2020 - Tabun (ethyl N,N-dimethylphosphoramidocyanidate), or GA, is a chemical warfare nerve agent produced during the World War II. The synthesis of its analogs is rather simple; thus, it is a significant threat. Furthermore, experiments with tabun and o...

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Drugs  9 results see all →

Clinicaltrials.gov  515 results

Acetylcholinesterase inhibition resulting from exposure to inhaled OP can be prevented ...
https://doi.org/10.1016/j.neuropharm.2020.108150
Neuropharmacology Rosenberg Y, Saxena A

May 22nd, 2020 - More frequent and widespread nerve agent attacks highlight the need for efficacious pre- and post-exposure organophosphate (OP) counter-measures to protect military and civilian populations. Because of critical targeting of acetylcholinesterase (A...

Efficient detoxification of nerve agents by oxime-assisted reactivation of acetylcholin...
https://doi.org/10.1016/j.neuropharm.2020.108111
Neuropharmacology Kovarik Z, Maček Hrvat N

Apr 25th, 2020 - The recent advancements in crystallography and kinetics studies involving reactivation mechanism of acetylcholinesterase (AChE) inhibited by nerve agents have enabled a new paradigm in the search for potent medical countermeasures in case of nerve...

Impairment of wound healing by reactive skin decontamination lotion (RSDL®) in a Göttin...
https://doi.org/10.1080/15569527.2020.1751183
Cutaneous and Ocular Toxicology; Connolly JM, Stevenson RS et. al.

Apr 23rd, 2020 - Reactive Skin Decontamination Lotion (RSDL®) is an FDA-approved skin decontamination kit carried by service members for removal and neutralisation of vesicants and nerve agents. The RSDL kit, comprised of a lotion-impregnated sponge, was shown to ...

Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surr...
https://doi.org/10.1111/nyas.14352
Annals of the New York Academy of Sciences References; Chambers JE, Meek EC

Apr 20th, 2020 - Oximes remain a long-standing element of the therapy for nerve agents, organophosphates (OPs) that poison by inhibiting the enzyme acetylcholinesterase (AChE), resulting in hypercholinergic activity both centrally and peripherally. Oximes, such as...

Molecular dynamics simulation of the electron ionization mass spectrum of tabun.
https://doi.org/10.1002/jms.4513
Journal of Mass Spectrometry : JMS REFERENCES; Chernicharo FCS, Modesto-Costa L et. al.

Mar 26th, 2020 - Tabun (ethyl N,N-dimethylphosphoramidocyanidate), or GA, is a chemical warfare nerve agent produced during the World War II. The synthesis of its analogs is rather simple; thus, it is a significant threat. Furthermore, experiments with tabun and o...

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News  11 results

Healthcare Providers Should Be Ready for Nerve Agent Attacks, Experts Say
https://www.medscape.com/viewarticle/906870

Dec 20th, 2018 - (Reuters Health) - Recent attacks in the UK and elsewhere using powerful nerve agents show that U.S. healthcare providers don't need to be near a battlefield to find themselves dealing with similar emergencies, researchers argue in a commentary th...

Healthcare providers should be ready for nerve agent attacks, experts say
https://www.reuters.com/article/us-health-emergencies-nerve-agents/healthcare-providers-should-be-ready-for-nerve-agent-attacks-experts-say-idUSKCN1OJ2PI

Dec 20th, 2018 - (Reuters Health) - - Recent attacks in the UK and elsewhere using powerful nerve agents show that U.S. healthcare providers don’t need to be near a battlefield to find themselves dealing with similar emergencies, researchers argue in a commentary ...

Medical charity MSF says treated patients for nerve agents after Syria attack
https://www.reuters.com/article/us-mideast-crisis-syria-sarin/medical-charity-msf-says-treated-patients-for-nerve-agents-after-syria-attack-idUSKBN1771T3

Apr 5th, 2017 - PARIS (Reuters) - Medical charity Medicins Sans Frontieres said on Wednesday eight people it treated following a suspected chemical attack in northern Syria had symptoms consistent with nerve agents like Sarin. “Among the victims of the attack on ...

Gulf War illness linked to chemical exposure
https://www.reuters.com/article/us-gulfwar-chemicals/gulf-war-illness-linked-to-chemical-exposure-idUSN1059348220080311

Mar 10th, 2008 - CHICAGO (Reuters) - Exposure to pesticides, nerve agents and other chemicals may explain the chronic, multi-symptom health problems experienced by up to one-third of Gulf War veterans, U.S. researchers said on Monday. A U.S. soldier stands guard a...

Gulf War illness linked to chemical exposure
https://www.reuters.com/article/us-gulfwar-chemicals/gulf-war-illness-linked-to-chemical-exposure-idUSN1059348220080310

Mar 10th, 2008 - CHICAGO (Reuters) - Exposure to pesticides, nerve agents and other chemicals may explain the chronic, multi-symptom health problems experienced by up to one-third of Gulf War veterans, U.S. researchers said on Monday. They said an analysis of a ho...

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Patient Education  1 results see all →