ALLMedicine™ Nerve Agents Center

Sep 8th, 2020 - Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to nerve agents can cause rapid death. In this review, we summarize the history of nerve agent development and use in warfare, the mechanisms by which these agents c...

Jul 28th, 2020 - V-nerve agents present information-poor spectra, both in GC-EI-MS and LC-ESI-MS/MS, with dominant fragments/product ions corresponding to the amine-containing residue. Hence, derivatives/isomers with the same amine residue exhibit similar mass spe...

Jul 28th, 2020 - The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous reports suggesting that metabolic processes could significantly contribute to toxicity. As ...

Jul 26th, 2020 - We present a simple method for chiral separation and analysis of organophosphorus nerve agents and apply it to monitor the enantioselective blood elimination kinetics of sarin in-vitro. The method is implemented in standard reverse phase LC-MS ope...

Jul 16th, 2020 - Nerve agents (NAs) produce acute and long-term brain injury and dysfunction, as evident from the Japan and Syria incidents. Magnetic resonance imaging (MRI) is a versatile technique to examine such chronic anatomical, functional, and neuronal dama...

Aug 30th, 2019 - The release of chemical agents can cause loss of life and result in major incidents. Chemical agent-related major incidents require a modified response by emergency services due to the chemicals' transmissibility, lethality, latency and persistenc...

Sep 8th, 2020 - Nerve agents are organophosphorus acetylcholinesterase inhibitors. Acute exposure to nerve agents can cause rapid death. In this review, we summarize the history of nerve agent development and use in warfare, the mechanisms by which these agents c...

Jul 28th, 2020 - V-nerve agents present information-poor spectra, both in GC-EI-MS and LC-ESI-MS/MS, with dominant fragments/product ions corresponding to the amine-containing residue. Hence, derivatives/isomers with the same amine residue exhibit similar mass spe...

Jul 28th, 2020 - The inhibition of acetylcholinesterase is regarded as the primary toxic mechanism of action for chemical warfare agents. Recently, there have been numerous reports suggesting that metabolic processes could significantly contribute to toxicity. As ...

Jul 26th, 2020 - We present a simple method for chiral separation and analysis of organophosphorus nerve agents and apply it to monitor the enantioselective blood elimination kinetics of sarin in-vitro. The method is implemented in standard reverse phase LC-MS ope...

Jul 16th, 2020 - Nerve agents (NAs) produce acute and long-term brain injury and dysfunction, as evident from the Japan and Syria incidents. Magnetic resonance imaging (MRI) is a versatile technique to examine such chronic anatomical, functional, and neuronal dama...

Dec 20th, 2018 - (Reuters Health) - - Recent attacks in the UK and elsewhere using powerful nerve agents show that U.S. healthcare providers don’t need to be near a battlefield to find themselves dealing with similar emergencies, researchers argue in a commentary ...

Apr 5th, 2017

Mar 10th, 2008 - CHICAGO (Reuters) - Exposure to pesticides, nerve agents and other chemicals may explain the chronic, multi-symptom health problems experienced by up to one-third of Gulf War veterans, U.S. researchers said on Monday. A U.S. soldier stands guard a...

Mar 10th, 2008 - CHICAGO (Reuters) - Exposure to pesticides, nerve agents and other chemicals may explain the chronic, multi-symptom health problems experienced by up to one-third of Gulf War veterans, U.S. researchers said on Monday. They said an analysis of a ho...

A drug that has been used to treat nerve gas and other types of pesticide and chemical poisoning in children off-label for years is now approved for pediatric use, the Food and Drug Administration announced on Sept. 9.