ALLMedicine™ Xanthomas Center

Jun 10th, 2021 - Familial hypercholesterolemia (FH) is characterized by high low-density lipoprotein (LDL) cholesterol levels, xanthomas including Achilles tendon thickening, and premature coronary artery disease (CAD). Carotid intima-media thickness (IMT) is a we...

May 13th, 2021 - Familial hypercholesterolemia (FH) is a genetic disorder characterized by high serum levels of low-density lipoprotein (LDL)-cholesterol (LDL-C), tendon and skin xanthomas, and premature coronary artery disease (CAD). In Japan, detailed informatio...

Apr 15th, 2021 - Cerebrotendinous xanthomatosis is a rare autosomal recessive lipid storage syndrome defined clinically by the triad of progressive neurodegeneration, juvenile cataracts and tendon xanthomas in adults. It is treatable, and a prompt diagnosis can im...

Apr 2nd, 2021 - Xanthomas present clinically as eruptive, tuberoeruptive, tuberous, tendinous, or planar forms. Among these, eruptive xanthoma (EX) is characterized by sudden development of multiple, red-to-yellow papules, each less than 5 mm in diameter, on the ...

Feb 25th, 2021 - Familial hypercholesterolemia (FH) is a relatively common inherited disorder caused by deleterious mutation(s) in the low-density lipoprotein (LDL) receptor or its associated genes. Given its nature as a heritable disease, any useful screening sch...

Jun 10th, 2021 - Familial hypercholesterolemia (FH) is characterized by high low-density lipoprotein (LDL) cholesterol levels, xanthomas including Achilles tendon thickening, and premature coronary artery disease (CAD). Carotid intima-media thickness (IMT) is a we...

May 13th, 2021 - Familial hypercholesterolemia (FH) is a genetic disorder characterized by high serum levels of low-density lipoprotein (LDL)-cholesterol (LDL-C), tendon and skin xanthomas, and premature coronary artery disease (CAD). In Japan, detailed informatio...

Apr 15th, 2021 - Cerebrotendinous xanthomatosis is a rare autosomal recessive lipid storage syndrome defined clinically by the triad of progressive neurodegeneration, juvenile cataracts and tendon xanthomas in adults. It is treatable, and a prompt diagnosis can im...

Apr 2nd, 2021 - Xanthomas present clinically as eruptive, tuberoeruptive, tuberous, tendinous, or planar forms. Among these, eruptive xanthoma (EX) is characterized by sudden development of multiple, red-to-yellow papules, each less than 5 mm in diameter, on the ...

Feb 25th, 2021 - Familial hypercholesterolemia (FH) is a relatively common inherited disorder caused by deleterious mutation(s) in the low-density lipoprotein (LDL) receptor or its associated genes. Given its nature as a heritable disease, any useful screening sch...

Jun 2nd, 2020 - Physical examination findings of individuals with heterozygous FH may include corneal arcus in individuals younger than 45 years; tendon xanthomas and tuberous xanthomas or xanthelasma that present at an early age should also trigger suspicion for...

Jun 2nd, 2020 - Figure 2. Xanthelasmata around the eyelids. Biopsy of cutaneous lesions, such as xanthomas and xanthelasmas, can be helpful in cases in which the diagnosis of FH is unclear. Xanthelasmas and xanthomas of FH will contain accumulated cholesterol, wh...

Jun 2nd, 2020 - Most patients (60%) with untreated heterozygous FH develop tendon xanthomas by the third decade of life. However, tendon xanthomas are not pathognomonic for heterozygous FH, and careful differential diagnosis is required. Tendon xanthomas in patie...

Feb 15th, 2018 - Cutaneous involvement was present in less than 1. 2% of patients with multiple myeloma (MM) and was associated with reduced overall survival, according to the results of a small, retrospective analysis.

May 26th, 2016 - Physical Examination Patients with very elevated LDL-C levels in whom Lp(a) is also high may present with other outward stigmata of dyslipidemia. Visualization of the eye may reveal evidence of severe dyslipidemia with arcus cornea.