×
About 490 results

ALLMedicine™ Protoporphyria Center

Research & Reviews  155 results

Marginal parental donors for pediatric living donor liver transplantation.
https://doi.org/10.1097/MOT.0000000000000990
Current Opinion in Organ Transplantation; Kasahara M, Sakamoto S et. al.

Nov 11th, 2022 - Living donor liver transplantation (LT) has been increasingly recognized as an effective treatment modality with excellent patient survival. Indications for LT have evolved not only for cholestatic liver disease, but also metabolic liver diseases....

Annular elastolytic giant cell granuloma in a woman with metabolic syndrome.
https://doi.org/10.5070/D328458521
Dermatology Online Journal; Abbas WF, Radionova EE et. al.

Oct 20th, 2022 - Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin condition. It belongs to a group of skin and elastic fiber disorders. When it affects sun-exposed skin, it is also called actinic granuloma. The etiology and pathogenesi...

Association of quality of life measures with afamelanotide treatment in patients with e...
https://doi.org/10.1016/j.jaad.2022.10.012
Journal of the American Academy of Dermatology; Ceresnie MS, Mohney L et. al.

Oct 17th, 2022 - Association of quality of life measures with afamelanotide treatment in patients with erythropoietic protoporphyria and x-linked protoporphyria: A retrospective cohort study.|2022|Ceresnie MS,Mohney L,Ko D,Lim HW,Mohammad TF,|

Iron Therapy in Erythropoietic Protoporphyria
https://clinicaltrials.gov/ct2/show/NCT05572125

Oct 10th, 2022 - Giving oral iron to patients with erythropoietic protoporphyria (EPP) who is iron deficient is thought to be beneficial. This is, however, not well documented. The purpose of this study is to investigate the effect and safety of oral iron in patie...

Implementation of a high-impact medication therapy subcommittee within a large academic...
https://doi.org/10.1093/ajhp/zxac259
American Journal of Health-system Pharmacy : AJHP : Offic... Mernick F, Akrap A et. al.

Sep 11th, 2022 - In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and autho...

see more →

Drugs  2 results see all →

Clinicaltrials.gov  17 results

Iron Therapy in Erythropoietic Protoporphyria
https://clinicaltrials.gov/ct2/show/NCT05572125

Oct 10th, 2022 - Giving oral iron to patients with erythropoietic protoporphyria (EPP) who is iron deficient is thought to be beneficial. This is, however, not well documented. The purpose of this study is to investigate the effect and safety of oral iron in patie...

Effect of Oral Cimetidine in the Protoporphyrias
https://clinicaltrials.gov/ct2/show/NCT05020184

Aug 11th, 2022 - Erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP) are genetic defects of heme biosynthesis that cause life-long, painful cutaneous sensitivity to light. EPP and XLP, collectively called the protoporphyrias, result in the accumu...

Study to Evaluate Efficacy, Safety, and Tolerability of MT-7117 in Subjects With Erythropoietic Protoporphyria or X-Linked Protoporphyria
https://clinicaltrials.gov/ct2/show/NCT04402489

Aug 8th, 2022 - The primary objective of this study is to investigate the efficacy of MT-7117 on time to onset and severity of first prodromal symptoms (burning, tingling, or stinging) associated with sunlight exposure in subjects with EPP or XLP aged 12-75.

Phase III Confirmatory Study in Erythropoietic Protoporphyria (EPP)
https://clinicaltrials.gov/ct2/show/NCT00979745

Oct 12th, 2021 - PURPOSE: To determine whether afamelanotide can reduce the severity of phototoxic reactions in patients with EPP. THEORETICAL FRAMEWORK: EPP is a genetic photosensitivity disorder where the mainstays of management are covering up from sunlight, sy...

see more →

News  21 results

July 2021 - What's the diagnosis?
https://www.mdedge.com/gihepnews/article/242413/mixed-topics/july-2021-whats-diagnosis
Luke J. Nayak, MD, Arjun R. Sondhi, MD et. al.

Jun 30th, 2021 - Answer: Erythropoietic protoporphyria. Figure B demonstrated massive cholestasis with brown deposits that represented protoporphyrin precipitates, which plugged the bile ducts and led to a cholestatic pattern of liver injury.

Photoprotection Recommended for People of Color
https://www.medscape.com/viewarticle/951252

May 17th, 2021 - Dermatologists and other clinicians should advise their patients with skin of color to practice sensible sun protection, including wearing protective clothing, staying in the shade when outdoors, and applying a tinted sunscreen with an SPF of 30 o...

Novel Oral Drug Improves Sunlight Tolerance in Patients With Erythropoietic Protoporphyria
https://www.medscape.com/viewarticle/936274

Aug 25th, 2020 - Dersimelagon, a novel once-daily oral selective melanocortin-1 receptor agonist, significantly boosted sunlight tolerance in patients with erythropoietic protoporphyria in a multicenter, phase 2, randomized trial, Kirstine Belongie, PhD, reported ...

Novel oral drug improves sunlight tolerance in patients with erythropoietic protoporphyria
https://www.mdedge.com/dermatology/article/227395/rare-diseases/novel-oral-drug-improves-sunlight-tolerance-patients
Bruce Jancin

Aug 24th, 2020 - Dersimelagon, a novel once-daily oral selective melanocortin-1 receptor agonist, significantly boosted sunlight tolerance in patients with erythropoietic protoporphyria in a multicenter, phase 2, randomized trial, Kirstine Belongie, PhD, reported.

Depressed Shiny Scars and Crusted Erosions
https://www.mdedge.com/dermatology/article/227045/dermatopathology/depressed-shiny-scars-and-crusted-erosions
Christina Dai, MD, Alison E. Seline, MD et. al.

Aug 16th, 2020 - The Diagnosis: Erythropoietic Protoporphyria Erythropoietic protoporphyria (EPP) is an autosomal-recessive photodermatosis that results from loss of activity of ferrochelatase, the last enzyme in the heme biosynthetic pathway. 1 Erythropoietic prot.

see more →

Patient Education  1 results see all →