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About 2,188 results

ALLMedicine™ Pyoderma Gangrenosum Center

Research & Reviews  743 results

Peristomal Pyoderma Gangrenosum at an Ileostomy Site
https://www.mdedge.com/dermatology/article/256571/rare-diseases/peristomal-pyoderma-gangrenosum-ileostomy-site
Anisha Guda, MD, Ted Rosen, MD

Jul 28th, 2022 - To the Editor: Peristomal pyoderma gangrenosum (PPG) is a rare entity first described in 1984. 1 Lesions usually begin as pustules that coalesce into an erythematous skin ulceration that contains purulent material.

Characterization of Legal Claims Involving Patients with Pyoderma Gangrenosum.
https://doi.org/10.1097/01.ASW.0000855052.83443.d8
Advances in Skin & Wound Care; Pfeifer HJ, Orfaly VE et. al.

Jul 28th, 2022 - To review of the litigation of literature related to patients with pyoderma gangrenosum (PG) to characterize the legal issues they face. Data sources include law databases Casetext and Lexis Nexis. All disability and medical liability claims direc...

A Study to Assess Adverse Events and Change in Disease State in Adult Participants Being Treated With Humira in Participants Diagnosed With Pyoderma Gangrenosum (PG)
https://clinicaltrials.gov/ct2/show/NCT04750213

Jul 28th, 2022 - Pyoderma Gangrenosum (PG) is a rapidly progressive disease and presents as painful, single or multiple lesions, with several clinical variants, in different locations, with a nonspecific histology, which makes the diagnosis challenging and often d...

Clinical efficacy of human split-thickness skin allograft in patients with pyoderma gan...
https://www.ncbi.nlm.nih.gov/pubmed/35881426
Wounds : a Compendium of Clinical Research and Practice; Anaeme AN, Darnall AR et. al.

Jul 27th, 2022 - Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disease that is characterized clinically by the development of painful pustules that subsequently progress to large cutaneous ulcers. There is no universally effective treatment for PG, an...

Exploratory Study of IFX-1 in Subjects With Pyoderma Gangrenosum
https://clinicaltrials.gov/ct2/show/NCT03971643

Jul 26th, 2022 - Neutrophilic dermatoses are a spectrum of inflammatory disorders characterized by skin lesions resulting from a neutrophil-rich inflammatory infiltrate in the absence of infection. Pyoderma gangrenosum is associated with a neutrophilic leukocytosi...

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Drugs  9 results see all →

Clinicaltrials.gov  29 results

A Study to Assess Adverse Events and Change in Disease State in Adult Participants Being Treated With Humira in Participants Diagnosed With Pyoderma Gangrenosum (PG)
https://clinicaltrials.gov/ct2/show/NCT04750213

Jul 28th, 2022 - Pyoderma Gangrenosum (PG) is a rapidly progressive disease and presents as painful, single or multiple lesions, with several clinical variants, in different locations, with a nonspecific histology, which makes the diagnosis challenging and often d...

Exploratory Study of IFX-1 in Subjects With Pyoderma Gangrenosum
https://clinicaltrials.gov/ct2/show/NCT03971643

Jul 26th, 2022 - Neutrophilic dermatoses are a spectrum of inflammatory disorders characterized by skin lesions resulting from a neutrophil-rich inflammatory infiltrate in the absence of infection. Pyoderma gangrenosum is associated with a neutrophilic leukocytosi...

Hyperbaric Oxygen Therapy for Pyoderma Gangrenosum
https://clinicaltrials.gov/ct2/show/NCT05343754

Jul 18th, 2022 - INTRODUCTION AND RATIONALE Pyoderma gangrenosum (PG) Background information Pyoderma gangrenosum (PG) is a rare, uncommon auto-inflammatory neutrophilic dermatosis characterized by a spectrum of clinical presentations including painful chronic and...

Phase 0/1 Local Application of the Monoclonal Antibody (Mab) sB24M in Patients With Purulent Pyoderma
https://clinicaltrials.gov/ct2/show/NCT04895566

Jul 11th, 2022 - This is an open-label Phase 0 trial that will enroll up to 10 participants with purulent pyoderma (chronic ulcerative pyoderma) by injecting 200 mg of the monoclonal antibody (Mab) sB24M into the areas affected by pyoderma. Monoclonal antibody (Ma...

An Open-Label, Proof-of-Concept Study of Ixekizumab in the Treatment of Pyoderma Gangrenosum
https://clinicaltrials.gov/ct2/show/NCT03137160

Jun 6th, 2022 - This is a Phase II study that will be open label and include a total of five patients who will receive the investigational product. These patients will have histological testing to rule out competing etiologies and require 3rd party adjudication/c...

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News  92 results

Peristomal Pyoderma Gangrenosum at an Ileostomy Site
https://www.mdedge.com/dermatology/article/256571/rare-diseases/peristomal-pyoderma-gangrenosum-ileostomy-site
Anisha Guda, MD, Ted Rosen, MD

Jul 28th, 2022 - To the Editor: Peristomal pyoderma gangrenosum (PPG) is a rare entity first described in 1984. 1 Lesions usually begin as pustules that coalesce into an erythematous skin ulceration that contains purulent material.

Rapidly Enlarging Bullous Plaque
https://www.mdedge.com/dermatology/article/252463/dermatopathology/rapidly-enlarging-bullous-plaque
Marina Kristy Ibraheim, MD, Katherine Martin, MD et. al.

Mar 7th, 2022 - The Diagnosis: Bullous Pyoderma Gangrenosum A bone marrow biopsy revealed 60% myeloblasts, leading to a diagnosis of acute myeloid leukemia (AML). A biopsy obtained from the edge of the bullous plaque demonstrated a dense dermal neutrophilic infil.

Large Leg Ulcers After Swimming in the Ocean
https://www.mdedge.com/dermatology/article/249007/infectious-diseases/large-leg-ulcers-after-swimming-ocean
Paul Macklis, MD, MS, Cory Pettit, MD et. al.

Nov 22nd, 2021 - The Diagnosis: Vibrio vulnificus Infection At the initial presentation, the differential diagnosis included infectious processes such as bacterial or angioinvasive fungal infections or an inflammatory process such as pyoderma gangrenosum. Blood cu.

Nonhealing incision and drainage site
https://www.mdedge.com/familymedicine/article/248539/dermatology/nonhealing-incision-and-drainage-site
MDedge Family Medicine;

Nov 11th, 2021 - Additional history from the family revealed that they were cleaning the wound with copious amounts of hydrogen peroxide twice a week—a practice that impedes wound healing and was ultimately the cause of this patient’s wound closure delay. A nonhea.

Skin ulcers can pose tricky diagnostic challenges
https://www.mdedge.com/dermatology/article/246224/wounds/skin-ulcers-can-pose-tricky-diagnostic-challenges
Doug Brunk

Sep 17th, 2021 - In the clinical opinion of Alex G. Ortega-Loayza, MD, MCR, few absolutes drive the initial assessment of patients who present with skin ulcers.

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Patient Education  2 results see all →