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About 2,273 results

ALLMedicine™ Pyoderma Gangrenosum Center

Research & Reviews  768 results

Limb amputation in patients with pyoderma gangrenosum: a multi-institutional case series.
https://doi.org/10.1007/s00403-022-02484-3
Archives of Dermatological Research; Shakshouk H, Lehman JS et. al.

Nov 30th, 2022 - Pyoderma gangrenosum (PG) can represent a diagnostic challenge, leading to missed or delayed diagnosis. With prolonged immunosuppressive therapy, the risk of infections is elevated, predisposing patients to receive anti-infective treatments and, i...

Pyoderma Gangrenosum Triggered by COVID-19 Vaccination in a Patient with Ulcerative Col...
https://doi.org/10.1177/15347346221141173
The International Journal of Lower Extremity Wounds; Kim YC, Shim HS et. al.

Nov 26th, 2022 - Pyoderma gangrenosum (PG) is a rare inflammatory skin disease that is difficult to diagnose. PG may be an extra-intestinal manifestation of ulcerative colitis (UC). In recent times, coronavirus disease (COVID-19) vaccines have caused various adver...

Negative-pressure wound therapy as an adjunct to treating pyoderma gangrenosum.
https://doi.org/10.1177/14782715221126768
The Journal of the Royal College of Physicians of Edinburgh; Mulholland O, Middleton D et. al.

Nov 13th, 2022 - Negative-pressure wound therapy has been shown to be effective in re-epithelialisation in recalcitrant pyoderma gangrenosum. This case documents a patient whose co-morbidities limited the standard treatment options and required an alternative mana...

Pyoderma Gangrenosum.
https://doi.org/10.1056/NEJMicm2204111
The New England Journal of Medicine; Zhou HY, Liu ZH

Nov 10th, 2022 - Pyoderma Gangrenosum.|2022|Zhou HY,Liu ZH,|diagnosis,

Clinical efficacy of flap transplantation combined with vacuum sealing drainage and met...
https://doi.org/10.1111/iwj.14003
International Wound Journal; Hao Y, He J et. al.

Nov 3rd, 2022 - This study was aimed to evaluate the clinical efficacy of flap transplantation combined with vacuum sealing drainage and methylprednisolone and cyclosporine in the treatment of ulcer wound of patients with pyoderma gangrenosum (PG). From August 20...

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Drugs  9 results see all →

Clinicaltrials.gov  29 results

Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)
https://clinicaltrials.gov/ct2/show/NCT04901325

Sep 2nd, 2022 - This is a Phase II study that will be open label and include a total of 20 patients who will receive the investigational product. PG will be defined by the investigator and a second reviewer on the basis of results from clinical, histological and ...

A Study to Assess Adverse Events and Change in Disease State in Adult Participants Being Treated With Humira in Participants Diagnosed With Pyoderma Gangrenosum (PG)
https://clinicaltrials.gov/ct2/show/NCT04750213

Aug 29th, 2022 - Pyoderma Gangrenosum (PG) is a rapidly progressive disease and presents as painful, single or multiple lesions, with several clinical variants, in different locations, with a nonspecific histology, which makes the diagnosis challenging and often d...

Exploratory Study of IFX-1 in Subjects With Pyoderma Gangrenosum
https://clinicaltrials.gov/ct2/show/NCT03971643

Jul 26th, 2022 - Neutrophilic dermatoses are a spectrum of inflammatory disorders characterized by skin lesions resulting from a neutrophil-rich inflammatory infiltrate in the absence of infection. Pyoderma gangrenosum is associated with a neutrophilic leukocytosi...

Hyperbaric Oxygen Therapy for Pyoderma Gangrenosum
https://clinicaltrials.gov/ct2/show/NCT05343754

Jul 18th, 2022 - INTRODUCTION AND RATIONALE Pyoderma gangrenosum (PG) Background information Pyoderma gangrenosum (PG) is a rare, uncommon auto-inflammatory neutrophilic dermatosis characterized by a spectrum of clinical presentations including painful chronic and...

Phase 0/1 Local Application of the Monoclonal Antibody (Mab) sB24M in Patients With Purulent Pyoderma
https://clinicaltrials.gov/ct2/show/NCT04895566

Jul 11th, 2022 - This is an open-label Phase 0 trial that will enroll up to 10 participants with purulent pyoderma (chronic ulcerative pyoderma) by injecting 200 mg of the monoclonal antibody (Mab) sB24M into the areas affected by pyoderma. Monoclonal antibody (Ma...

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News  93 results

Cracking the “MGUS” Code Reveals Monoclonal Gammopathy of Clinical Significance:
https://www.onclive.com/view/cracking-the-mgus-code-reveals-monoclonal-gammopathy-of-clinical-significance-

Nov 1st, 2022 - When assessing monoclonal gammopathy it is important to rule out clinically significant associations requiring treatment. On initial patient consultation, gathering a detailed patient history and thorough physical exam can catch clinically signifi...

Peristomal Pyoderma Gangrenosum at an Ileostomy Site
https://www.mdedge.com/dermatology/article/256571/rare-diseases/peristomal-pyoderma-gangrenosum-ileostomy-site
Anisha Guda, MD, Ted Rosen, MD

Jul 28th, 2022 - To the Editor: Peristomal pyoderma gangrenosum (PPG) is a rare entity first described in 1984. 1 Lesions usually begin as pustules that coalesce into an erythematous skin ulceration that contains purulent material.

Rapidly Enlarging Bullous Plaque
https://www.mdedge.com/dermatology/article/252463/dermatopathology/rapidly-enlarging-bullous-plaque
Marina Kristy Ibraheim, MD, Katherine Martin, MD et. al.

Mar 7th, 2022 - The Diagnosis: Bullous Pyoderma Gangrenosum A bone marrow biopsy revealed 60% myeloblasts, leading to a diagnosis of acute myeloid leukemia (AML). A biopsy obtained from the edge of the bullous plaque demonstrated a dense dermal neutrophilic infil.

Large Leg Ulcers After Swimming in the Ocean
https://www.mdedge.com/dermatology/article/249007/infectious-diseases/large-leg-ulcers-after-swimming-ocean
Paul Macklis, MD, MS, Cory Pettit, MD et. al.

Nov 22nd, 2021 - The Diagnosis: Vibrio vulnificus Infection At the initial presentation, the differential diagnosis included infectious processes such as bacterial or angioinvasive fungal infections or an inflammatory process such as pyoderma gangrenosum. Blood cu.

Nonhealing incision and drainage site
https://www.mdedge.com/familymedicine/article/248539/dermatology/nonhealing-incision-and-drainage-site
MDedge Family Medicine;

Nov 11th, 2021 - Additional history from the family revealed that they were cleaning the wound with copious amounts of hydrogen peroxide twice a week—a practice that impedes wound healing and was ultimately the cause of this patient’s wound closure delay. A nonhea.

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Patient Education  10 results see all →