×
About 528 results

ALLMedicine™ Xanthomas Center

Research & Reviews  186 results

Causes and Natural History of Dyslipidemias
https://clinicaltrials.gov/ct2/show/NCT00353782

May 13th, 2022 - The lipoprotein transport system is vital to the delivery of the hydrophobic fats that are carried in the aqueous environment of the blood. The lipoprotein particles that comprise this system are polydisperse and contain triglycerides, free and es...

An update on lipid apheresis for familial hypercholesterolemia.
https://doi.org/10.1007/s00467-022-05541-1 10.3181/00379727-80-19629 10.1016/s0140-6736(76)93089-0 10.1046/j.1537-2995.1999.39399219285.x 10.1172/JCI107332 10.1172/JCI114531 10.1016/j.jacc.2020.03.057 10.2147/tacg.s8285 10.1093/aje/kwh236 10.5551/jat.CR003 10.1210/jc.2002-021487 10.1016/j.atherosclerosis.2012.02.019 10.1016/j.atherosclerosis.2013.12.020 10.1016/j.amjcard.2008.07.035 10.1136/hrt.80.6.583 10.1016/S0140-6736(04)15467-6 10.1016/j.amjcard.2020.09.015 10.1097/CRD.0000000000000014 10.1016/j.pcad.2015.04.004 10.1056/NEJM198006263022607 10.1016/j.atherosclerosis.2009.06.010 10.1046/j.1526-0968.2001.00328.x 10.1046/j.1526-0968.2003.00073.x 10.1371/journal.pone.0101290 10.1097/01.ccx.0000244119.16377.75 10.1016/S1567-5688(09)71812-4 10.1111/j.1744-9987.2006.00441.x 10.1161/01.cir.96.5.1381 10.1007/s00467-018-3906-6 10.1016/j.jacl.2016.08.006 10.1161/CIRCULATIONAHA.106.671016 10.1161/01.cir.0000058166.99182.54 10.1016/j.jacc.2016.03.520 10.4158/EP171764.APPGL 10.1016/j.atherosclerosis.2011.06.016 10.1093/eurheartj/ehu274 10.1093/eurheartj/eht273 10.1093/eurheartj/ehz455 10.1002/jca.21743 10.1111/1744-9987.13799 10.1111/trf.14479 10.1111/trf.15512
Pediatric Nephrology (Berlin, Germany); Taylan C, Weber LT

Apr 26th, 2022 - Familial hypercholesterolemia (FH) is an inherited metabolic defect leading to increased total cholesterol and low-density cholesterol (LDL) from birth onwards. Homozygous FH, presenting with clear clinical features, has a prevalence of ~ 1 per mi...

Cerebrotendinous Xanthomatosis - GeneReviews® - NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/n/gene/ctx/

Mar 17th, 2022 - Cerebrotendinous xanthomatosis (CTX) is a lipid storage disease characterized by infantile-onset diarrhea, childhood-onset cataract, adolescent- to young adult-onset tendon xanthomas, and adult-onset progressive neurologic dysfunction (dementia, p...

New diagnosis of diabetes and severe hyperlipidemia at 3 months postpartum presenting a...
https://doi.org/10.1111/jog.15123
The Journal of Obstetrics and Gynaecology Research; Zhen XM, Lee KL et. al.

Feb 3rd, 2022 - A 33-year-old woman presented to the Emergency Department at 3 months postpartum with a 2-day history of a partial left sixth cranial nerve palsy, and several weeks' history of bilateral blurred vision and papular skin lesions. Brain imaging and u...

Association between Achilles Tendon Softness and Atherosclerotic Cardiovascular Disease...
https://doi.org/10.5551/jat.63151
Journal of Atherosclerosis and Thrombosis; Michikura M, Ogura M et. al.

Jan 12th, 2022 - Achilles tendon (AT) xanthomas are a specific physical finding of familial hypercholesterolemia (FH) and AT thickness has been used for its diagnosis and evaluation of its severity. Recently, we reported that the AT of FH patients was softer than ...

see more →

Clinicaltrials.gov  5 results

Causes and Natural History of Dyslipidemias
https://clinicaltrials.gov/ct2/show/NCT00353782

May 13th, 2022 - The lipoprotein transport system is vital to the delivery of the hydrophobic fats that are carried in the aqueous environment of the blood. The lipoprotein particles that comprise this system are polydisperse and contain triglycerides, free and es...

Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada
https://clinicaltrials.gov/ct2/show/NCT02009345

Oct 12th, 2021 - Familial hypercholesterolemia (FH) is a genetic lipoprotein disorder characterized by elevations in low-density lipoprotein cholesterol (LDL-C) >95th percentile for age and gender. Affected individuals may show clinical manifestations (xanthomas, ...

A Registration Study for Familial Hypercholesterolemia in Taiwan
https://clinicaltrials.gov/ct2/show/NCT03152656

May 15th, 2017 - Familial hypercholesterolemia (FH) is an inherited disorder of lipoprotein metabolism, transmitted in an autosomal dominant manner and clinically characterized by elevated levels of total cholesterol (TC) and low-density lipoprotein (LDL) choleste...

Cardiovascular Disease in FH Heterozygous
https://clinicaltrials.gov/ct2/show/NCT01783405

Jun 10th, 2014 - Familial hypercholesterolemia (FH) is the most common autosomal dominant disease in most countries, including Spain. Its prevalence is estimated at one in every 350-500 people being higher in certain areas with certain genetic isolation as French ...

Cholestanol in Humans
https://clinicaltrials.gov/ct2/show/NCT00018694

Oct 14th, 2013 - Cerebrotendinous xanthomatosis is a recessively inherited in born of bile acid synthesis due to a mutation in sterol 27-hydroxylase (CYP27A1). Patients with this disease suffer from xanthomas located in the brain and tendon, accelerated atheroscle...

see more →

News  19 results

Fast Five Quiz: Heterozygous Familial Hypercholesterolemia Presentation and Diagnosis
https://reference.medscape.com/viewarticle/930070_3

Jun 3rd, 2020 - Most patients (60%) with untreated heterozygous FH develop tendon xanthomas by the third decade of life. However, tendon xanthomas are not pathognomonic for heterozygous FH, and careful differential diagnosis is required. Tendon xanthomas in patie...

Fast Five Quiz: Heterozygous Familial Hypercholesterolemia Presentation and Diagnosis
https://reference.medscape.com/viewarticle/930070_6

Jun 3rd, 2020 - Figure 2. Xanthelasmata around the eyelids. Biopsy of cutaneous lesions, such as xanthomas and xanthelasmas, can be helpful in cases in which the diagnosis of FH is unclear. Xanthelasmas and xanthomas of FH will contain accumulated cholesterol, wh...

Fast Five Quiz: Heterozygous Familial Hypercholesterolemia Presentation and Diagnosis
https://reference.medscape.com/viewarticle/930070_2

Jun 3rd, 2020 - Physical examination findings of individuals with heterozygous FH may include corneal arcus in individuals younger than 45 years; tendon xanthomas and tuberous xanthomas or xanthelasma that present at an early age should also trigger suspicion for...

'What Are These Bumps I See All Over?'
https://www.staging.medscape.com/viewarticle/893920

Mar 22nd, 2018 - Charles P. Vega, MD: A 55-year-old woman comes to see her primary care physician with a chief complaint of "What are all these bumps I see all over?" She has noted an increasing number of asymptomatic, small yellow and red papules on her buttocks ...

'What Are These Bumps I See All Over?'
https://www.medscape.com/viewarticle/893920

Mar 22nd, 2018 - Charles P. Vega, MD: A 55-year-old woman comes to see her primary care physician with a chief complaint of "What are all these bumps I see all over?" She has noted an increasing number of asymptomatic, small yellow and red papules on her buttocks ...

see more →

Patient Education  1 results see all →