About 795 results

ALLMedicine™ Drooling Center

Research & Reviews  235 results

Placebo-Controlled Clinical Trial of IncobotulinumtoxinA for Sialorrhea in Children: SI...
Neurology Berweck S, Bonikowski M et. al.

Aug 4th, 2021 - This prospective phase III study (SIPEXI) investigated efficacy and safety of repeated injections of incobotulinumtoxinA (incoBoNT/A) for treatment of chronic sialorrhea (drooling) associated with neurological disorders (e.g., cerebral palsy, trau...

The Pediatric Infectious Disease Journal; de Koff EM, Euser SM et. al.

Jul 15th, 2021 - We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% C...

Effect of orofacial physiotherapeutic and hygiene interventions on oral health related ...
Journal of Oral Rehabilitation; Baram S, Karlsborg M et. al.

Jun 16th, 2021 - Parkinson's disease (PD) has a negative effect on oral health and orofacial function, but the subjective experience of orofacial symptoms and their impact on the quality of life is not fully investigated. In addition, knowledge of how to improve t...

Cannabis induced thermal epiglottitis in a pediatric patient.
The American Journal of Emergency Medicine; Rao SJ, Kirse DJ et. al.

Jun 8th, 2021 - Acute epiglottitis is an airway emergency presenting with edema and inflammation of the epiglottis and aryepiglottic folds [1]. Infectious and other non-infectious etiologies may cause significant airway injury presenting with similar clinical sym...

Natural history of alpha-thalassemia X-linked intellectual disability syndrome: A case ...
American Journal of Medical Genetics. Part A; Arvio M, Lähdetie J

May 5th, 2021 - We have followed the clinical course of a 45-year-old man with a severe form of alpha-thalassemia X-linked intellectual disability syndrome for 40 years. The most challenging health issue is the combination of rumination, drooling, and vomiting. T...

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Drugs  32 results see all →

Clinicaltrials.gov  11 results

Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disab...

Oct 29th, 2018 - The objective of this study is to investigate the efficacy and safety of NT 201 compared with placebo for the treatment of chronic troublesome sialorrhea associated with neurological disorders (e.g. cerebral palsy, traumatic brain injury) and/or i...

Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects

Jun 1st, 2018 - This study will evaluate the efficacy and safety of MYOBLOC in the treatment of Sialorrhea (drooling), which can be a symptom of many disease conditions. MYOBLOC will be injected directly into the salivary glands. MYOBLOC has been shown in previou...

Lengthening Temporalis Myoplasty and Improvement of Primary Swallowing Disorders in Facial Paralysis

Oct 27th, 2017 - The facial paralysis is a frequent disease causing important functionals swallowing dysfunctions. The purpose of our study was to evaluate the improvement of the swallowing disorders after surgery by lengthening temporalis myoplasty (LTM) in the f...

Botulinum Toxin-A for Sialorrhoea Treatment in Asian Adults With Neurological Diseases

Apr 23rd, 2015 - Study Objectives: To determine the efficacy, safety, tolerability and adverse effects of three doses of Dysport® (50MU, 100MU and 200MU) in the treatment of sialorrhoea in Asian patients with neurological disorders/diseases and to determine the mo...

Efficacy of Passive Oral Motor Therapy on Drooling in Children With Multiple Disabilities

Jan 8th, 2015 - Title To formulate and see efficacy of passive oral motor regimen for drooling in children with multiple disabilities Background Drooling ranges from mild embarrassment and discomfort for the intellectually intact patient with minimal drooling to ...

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News  31 results

Excessive Drooling a Sign of Greater Dysfunction in Parkinson's Disease

Jun 24th, 2021 - Excessive drooling by patients with advanced Parkinson's disease is an indicator of greater motor and nonmotor dysfunction, new research shows. "Sialorrhea is not just a cosmetic problem," study investigator Francesca Morgante, MD, associate profe...

An Unvaccinated Girl With Wheezing After Foreign Body Removal

Feb 10th, 2020 - Question 1 of 2 Which of the following signs or symptoms is more commonly associated with an impacted esophageal foreign body? Your Peers Chose: Absence of drool 0% Chest pain 0% Diarrhea 0% Lower abdominal pain 0% When present, symptoms of esopha...

Pseudo-Ludwig angina
Andrew Tiu, MD, Kamolyut Lapumnuaypol, MD

Sep 3rd, 2019 - An 83-year-old woman with hypertension, hypothyroidism, and a history of depression presented to the emergency department with acute shortness of breath and hypoxia. She was found to have submassive pulmonary embolism, and a heparin infusion was s.

FDA OKs IncobotulinumtoxinA (Xeomin) First-Line in Blepharospasm

May 13th, 2019 - PHILADELPHIA — The US Food and Drug Administration (FDA) has approved broadening the indication for incobotulinumtoxinA (Xeomin, Merz Pharmaceuticals) as first-line therapy for blepharospasm in adult patients, the manufacturer has announced. Benig...

Drug Derived from Botulinum Toxin Curbs Excessive Drooling

Apr 8th, 2019 - IncobotulinumtoxinA (Xeomin, Merz Pharmaceutials) injected into the salivary glands provides lasting improvement in chronic sialorrhea (excessive drooling), new research shows. Results of the Sialorrhea in Adults Xeomin Investigation (SIAXI) study...

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Patient Education  9 results see all →