ALLMedicine™ Adrenal Crisis Center

May 8th, 2021 - Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis. We describe the case of a 45-year-...

Apr 9th, 2021 - Adrenal crisis is a life-threatening manifestation of acute adrenal insufficiency. One of the most important underlying causes is Addison disease (primary adrenal insufficiency).A 42-year-old White woman with a medical history of Addison disease o...

Mar 26th, 2021 - The hypothalamo-pituitary-adrenal (HPA) axis is one of the main components of the stress system. Maintenance of normal physiological events, which include stress responses to internal or external stimuli in the body, depends on appropriate HPA axi...

Mar 25th, 2021 - A 53-year-old man presented with 6 months history of weight loss associated with nausea, fatigue, dizziness and headache. On arrival he was in adrenal crisis. Biochemistry revealed anterior hypopituitarism with low cortisol, thyroxine, testosteron...

Mar 4th, 2021 - Adrenal insufficiency (AI) is a life-threatening condition requiring life-long glucocorticoid (GC) substitution therapy, as well as stress adaptation to prevent adrenal crises. The number of individuals with primary and secondary adrenal insuffici...

Jun 27th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Aug 31st, 2016 - Acute adrenal insufficiency, also termed adrenal crisis, is a life-threatening endocrine emergency brought about by a lack of production of the adrenal hormone cortisol, the major glucocorticoid. Identifying patients at risk and prompt management.

Jun 28th, 2016 - This clinical practice guideline of the diagnosis and treatment of adrenal insufficiency (AI) including adrenal crisis was produced on behalf of the Japan Endocrine Society. This evidence-based guideline was developed by a committee including all ...

May 8th, 2021 - Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis. We describe the case of a 45-year-...

Apr 9th, 2021 - Adrenal crisis is a life-threatening manifestation of acute adrenal insufficiency. One of the most important underlying causes is Addison disease (primary adrenal insufficiency).A 42-year-old White woman with a medical history of Addison disease o...

Mar 26th, 2021 - The hypothalamo-pituitary-adrenal (HPA) axis is one of the main components of the stress system. Maintenance of normal physiological events, which include stress responses to internal or external stimuli in the body, depends on appropriate HPA axi...

Mar 25th, 2021 - A 53-year-old man presented with 6 months history of weight loss associated with nausea, fatigue, dizziness and headache. On arrival he was in adrenal crisis. Biochemistry revealed anterior hypopituitarism with low cortisol, thyroxine, testosteron...

Mar 4th, 2021 - Adrenal insufficiency (AI) is a life-threatening condition requiring life-long glucocorticoid (GC) substitution therapy, as well as stress adaptation to prevent adrenal crises. The number of individuals with primary and secondary adrenal insuffici...

Feb 22nd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

Oct 24th, 2016 - Action Points Adrenal suppression (AS) following glucocorticoid (GC) therapy in children with rheumatic diseases is common and persistent. Note that some individuals with AS can experience biochemical changes without exhibiting symptoms, leading t...

Jun 3rd, 2016 - Steroid Dysregulation Steroid dysregulation, either endogenous or iatrogenic in nature, has been reported to cause neuropsychiatric symptoms. Major depression with psychotic features can be an initial presentation of Cushing disease, especially in.

Mar 11th, 2016 - The Endocrine Society guidelines for diagnosis and treatment of primary adrenal insufficiency recommend that acutely ill patients with unexplained symptoms have diagnostic testing to rule out primary adrenal insufficiency, those who have severe sy.

Jan 20th, 2016 - The first-ever guidelines from the Endocrine Society on diagnosis and management of primary adrenal insufficiency (PAI) call for the use of the high-dose corticotropin stimulatory test as the gold standard for diagnosis in adults, hydrocortisone a...