ALLMedicine™ Adrenal Crisis Center

Mar 4th, 2021 - Adrenal insufficiency (AI) is a life-threatening condition requiring life-long glucocorticoid (GC) substitution therapy, as well as stress adaptation to prevent adrenal crises. The number of individuals with primary and secondary adrenal insuffici...

Feb 18th, 2021 - Secondary adrenal insufficiency (AI) occurs as the result of any process that disrupts normal hypothalamic and/or anterior pituitary function and causes a decrease in the secretion of steroid hormones from the adrenal cortex. The most common cause...

Feb 17th, 2021 - Mortality data in patients with adrenal insufficiency are inconsistent, possibly due to temporal and geographical differences between patients and their reference populations. To compare mortality risk and causes of death in adrenal insufficiency ...

Dec 29th, 2020 - Bilateral adrenal haemorrhage is a rare and often fatal condition that most commonly occurs under conditions of severe physiological stress. We describe a 33-year-old male patient with ulcerative colitis who presented with acute worsening epigastr...

Dec 28th, 2020 - Patients with rheumatic diseases are often treated with prolonged, high-dose systemic glucocorticoids which can cause hypothalamic-pituitary-adrenal (HPA) axis suppression and development of tertiary adrenal insufficiency. Adrenal insufficiency ca...

Jun 27th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Aug 31st, 2016 - Acute adrenal insufficiency, also termed adrenal crisis, is a life-threatening endocrine emergency brought about by a lack of production of the adrenal hormone cortisol, the major glucocorticoid. Identifying patients at risk and prompt management.

Jun 28th, 2016 - This clinical practice guideline of the diagnosis and treatment of adrenal insufficiency (AI) including adrenal crisis was produced on behalf of the Japan Endocrine Society. This evidence-based guideline was developed by a committee including all ...

Mar 4th, 2021 - Adrenal insufficiency (AI) is a life-threatening condition requiring life-long glucocorticoid (GC) substitution therapy, as well as stress adaptation to prevent adrenal crises. The number of individuals with primary and secondary adrenal insuffici...

Feb 22nd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

Feb 18th, 2021 - Secondary adrenal insufficiency (AI) occurs as the result of any process that disrupts normal hypothalamic and/or anterior pituitary function and causes a decrease in the secretion of steroid hormones from the adrenal cortex. The most common cause...

Feb 17th, 2021 - Mortality data in patients with adrenal insufficiency are inconsistent, possibly due to temporal and geographical differences between patients and their reference populations. To compare mortality risk and causes of death in adrenal insufficiency ...

Dec 29th, 2020 - Bilateral adrenal haemorrhage is a rare and often fatal condition that most commonly occurs under conditions of severe physiological stress. We describe a 33-year-old male patient with ulcerative colitis who presented with acute worsening epigastr...

Feb 22nd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

Oct 24th, 2016 - Action Points Adrenal suppression (AS) following glucocorticoid (GC) therapy in children with rheumatic diseases is common and persistent. Note that some individuals with AS can experience biochemical changes without exhibiting symptoms, leading t...

Jun 3rd, 2016 - Steroid Dysregulation Steroid dysregulation, either endogenous or iatrogenic in nature, has been reported to cause neuropsychiatric symptoms. Major depression with psychotic features can be an initial presentation of Cushing disease, especially in.

Mar 11th, 2016 - The Endocrine Society guidelines for diagnosis and treatment of primary adrenal insufficiency recommend that acutely ill patients with unexplained symptoms have diagnostic testing to rule out primary adrenal insufficiency, those who have severe sy.

Jan 20th, 2016 - The first-ever guidelines from the Endocrine Society on diagnosis and management of primary adrenal insufficiency (PAI) call for the use of the high-dose corticotropin stimulatory test as the gold standard for diagnosis in adults, hydrocortisone a...