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About 3,743 results

ALLMedicine Growth Hormone Deficiency Center

Research & Reviews  1,757 results

Expanding the phenotype of biallelic RNPC3 variants associated with growth hormone defi...
https://doi.org/10.1002/ajmg.a.61632
American Journal of Medical Genetics. Part A REFERENCES; Verberne EA, Faries S et. al.

May 27th, 2020 - Pathogenic variants in components of the minor spliceosome have been associated with several human diseases. Recently, it was reported that biallelic RNPC3 variants lead to severe isolated growth hormone deficiency and pituitary hypoplasia. The RN...

Growth hormone therapy for people with thalassaemia.
https://doi.org/10.1002/14651858.CD012284.pub3
The Cochrane Database of Systematic Reviews References; Ngim CF, Lai NM et. al.

May 27th, 2020 - Thalassaemia is a recessively-inherited blood disorder that leads to anaemia of varying severity. In those affected by the more severe forms, regular blood transfusions are required which may lead to iron overload. Accumulated iron from blood tran...

A novel diagnostic tool for the evaluation of hypothalamic-pituitary region and diagnos...
https://doi.org/10.1515/jpem-2019-0321
Journal of Pediatric Endocrinology & Metabolism : JPEM; Demiral M, Salih Karaca M et. al.

May 20th, 2020 - Backgrounds Limitations in the evaluation of the pituitary size and changes according to pubertal status make its validity questionable. Recently, in a small-scale study, pons ratio (PR) has been suggested as a more sensitive tool for diagnosis an...

How to interpret IGF-1 and growth hormone stimulation tests.
https://doi.org/10.1136/archdischild-2019-318466
Archives of Disease in Childhood. Education and Practice Edition; Tseretopoulou X, Mushtaq T

May 4th, 2020 - You are seeing an 11-year-old boy in a general paediatric clinic referred with short stature. His height is below the 0.4th centile. The mid-parental height is on 50th centile. Baseline investigations, including renal and liver function, coeliac s...

Biochemical bone turnover markers in hormonal disorders in adults: a narrative review.
https://doi.org/10.1007/s40618-020-01269-7
Journal of Endocrinological Investigation; Szulc P

Apr 26th, 2020 - Hormonal disorders are often associated with abnormal levels of bone turnover markers (BTMs). N-terminal propeptide of type I procollagen (PINP) and serum C-terminal cross-linking telopeptide of type I collagen (CTX-I) are the reference markers of...

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Guidelines  4 results

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO...
https://journals.aace.com/doi/full/10.4158/GL-2019-0405
Endocrine Practice; Yuen KCJ,et al

Oct 31st, 2019 - The development of these guidelines is sponsored by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols for the sta...

Growth hormone treatment of adolescents with growth hormone deficiency (GHD) during the...
https://doi.org/10.1007/s40618-014-0201-7
Journal of Endocrinological Investigation; Aimaretti G, Attanasio R et. al.

Nov 4th, 2014 - Treatment of adolescents with growth hormone deficiency (GHD) during the transition period is a controversial issue. This paper is a contribution from the Italian community of paediatric and adult endocrinologists surveyed in a Delphi panel. The D...

Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clini...
https://doi.org/10.1210/jc.2011-0179
The Journal of Clinical Endocrinology and Metabolism; Molitch ME, Clemmons DR et. al.

May 23rd, 2011 - The aim was to update The Endocrine Society Clinical Practice Guideline on Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published in 2006. Consensus was guided by systematic reviews of evidence and discussions throu...

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS MEDICAL GUIDELINES FOR CLINICAL PRACTICE F...
https://www.aace.com/files/growth-hormone-guidelines.pdf
David M. Cook

Sep 30th, 2009 - This report consists of recommendations for indications, diagnosis, and clinical use of GH in patients with biochemically proven GHD in transition years and in adulthood. However, it must be emphasized that physicians should use these guidelines c.

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Drugs  21 results see all →

Clinicaltrials.gov  1,863 results

Expanding the phenotype of biallelic RNPC3 variants associated with growth hormone defi...
https://doi.org/10.1002/ajmg.a.61632
American Journal of Medical Genetics. Part A REFERENCES; Verberne EA, Faries S et. al.

May 27th, 2020 - Pathogenic variants in components of the minor spliceosome have been associated with several human diseases. Recently, it was reported that biallelic RNPC3 variants lead to severe isolated growth hormone deficiency and pituitary hypoplasia. The RN...

Growth hormone therapy for people with thalassaemia.
https://doi.org/10.1002/14651858.CD012284.pub3
The Cochrane Database of Systematic Reviews References; Ngim CF, Lai NM et. al.

May 27th, 2020 - Thalassaemia is a recessively-inherited blood disorder that leads to anaemia of varying severity. In those affected by the more severe forms, regular blood transfusions are required which may lead to iron overload. Accumulated iron from blood tran...

A novel diagnostic tool for the evaluation of hypothalamic-pituitary region and diagnos...
https://doi.org/10.1515/jpem-2019-0321
Journal of Pediatric Endocrinology & Metabolism : JPEM; Demiral M, Salih Karaca M et. al.

May 20th, 2020 - Backgrounds Limitations in the evaluation of the pituitary size and changes according to pubertal status make its validity questionable. Recently, in a small-scale study, pons ratio (PR) has been suggested as a more sensitive tool for diagnosis an...

How to interpret IGF-1 and growth hormone stimulation tests.
https://doi.org/10.1136/archdischild-2019-318466
Archives of Disease in Childhood. Education and Practice Edition; Tseretopoulou X, Mushtaq T

May 4th, 2020 - You are seeing an 11-year-old boy in a general paediatric clinic referred with short stature. His height is below the 0.4th centile. The mid-parental height is on 50th centile. Baseline investigations, including renal and liver function, coeliac s...

Biochemical bone turnover markers in hormonal disorders in adults: a narrative review.
https://doi.org/10.1007/s40618-020-01269-7
Journal of Endocrinological Investigation; Szulc P

Apr 26th, 2020 - Hormonal disorders are often associated with abnormal levels of bone turnover markers (BTMs). N-terminal propeptide of type I procollagen (PINP) and serum C-terminal cross-linking telopeptide of type I collagen (CTX-I) are the reference markers of...

see more →

News  97 results

Growth Hormone Deficiency Clinical Practice Guidelines (AACE/ACE, 2019)
https://www.medscape.com/viewarticle/924401

Jan 30th, 2020 - Guidelines for the management of growth hormone deficiency in adults and patients transitioning from pediatric to adult care were published in 2019 by the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinolo...

Don't Use Growth Hormone for Anti-Aging, Say New Guidelines
https://www.medscape.com/viewarticle/922195

Dec 4th, 2019 - The 2019 Guidelines for Management of Growth Hormone Deficiency in Adults and Patients Transitioning from Pediatric to Adult Care issued by two key US endocrine societies cover important developments in the decade since the previous version.   The...

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY GUIDELINES FOR MANAGEMENT OF GROWTH HORMONE DEFICIENCY IN ADULTS AND PATIENTS TRANSITIONING FROM PEDIATRIC TO...
https://journals.aace.com/doi/full/10.4158/GL-2019-0405
Endocrine Practice; Yuen KCJ,et al

Oct 31st, 2019 - The development of these guidelines is sponsored by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols for the sta...

New insights, advances offer better perspective on AGHD
https://www.mdedge.com/familymedicine/article/200908/pituitary-thyroid-adrenal-disorders/new-insights-advances-offer-better?channel=39313
MDedge Endocrinology; Randy Dotinga

May 14th, 2019 - LOS ANGELES – Recent research, a new test, and upcoming guidelines are providing insight into the diagnosis of adult growth hormone deficiency and the importance of treatment, Kevin C. J.

Macimorelin for Diagnosis of Adult Growth Hormone Deficiency in EU
https://www.medscape.com/viewarticle/905314

Nov 18th, 2018 - The Committee for Medicinal Products for Human Use of the European Medicines Agency (EMA) has issued a positive opinion on an orally available ghrelin agonist macimorelin (Macimorelin, Aeterna Zentaris) to be used in the diagnosis of patients with...

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Patient Education  1 results see all →