×
About 333 results

ALLMedicine™ Hyperglucagonemia Center

Research & Reviews  165 results

A review of the Efficacy and Cardiovascular Safety of Amylin Analogues.
https://doi.org/10.2174/1574886315999201105153852
Current Drug Safety; Koshy RM, Fernandez CJ et. al.

Nov 6th, 2020 - A large proportion of persons with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) do not reach the glycosylated haemoglobin (HbA1c) target of < 7% (53 mmol/mol) with an increasing proportion of them being overweight or obese. ...

Pseudo-hyperglucagonemia was observed in pancreatectomized patients when measured by gl...
https://doi.org/10.1111/jdi.13325
Journal of Diabetes Investigation References; Kobayashi M, Waki H et. al.

Jun 17th, 2020 - Glucagon is detected in plasma even after total pancreatectomy, and it is debated whether this glucagon is derived from the gastrointestinal tract. Here, we applied sandwich enzyme-linked immunosorbent assay (ELISA) and liquid chromatography-high-...

Effect of short-term intensive insulin therapy on α-cell function in patients with newl...
https://doi.org/10.1097/MD.0000000000019685
Medicine Zheng HL, Xing Y et. al.

Apr 3rd, 2020 - The effect of intensive insulin therapy on hyperglucagonemia in newly diagnosed type 2 diabetes (T2DM), and its associations with β-cell function, has not been elucidated. This study assessed the effect of 12 weeks of intensive insulin therapy on ...

Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic ...
https://doi.org/10.2337/db19-0715
Diabetes Suppli MP, Bagger JI et. al.

Jan 24th, 2020 - Glucagon secretion is regulated by circulating glucose, but it has turned out that amino acids also play an important role and that hepatic amino acid metabolism and glucagon are linked in a mutual feedback cycle, the liver-α-cell axis. On the bas...

A Primary Role for α-Cells as Amino Acid Sensors.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085241
Diabetes Dean ED

Oct 27th, 2019 - Glucagon and its partner insulin are dually linked in both their secretion from islet cells and their action in the liver. Glucagon signaling increases hepatic glucose output, and hyperglucagonemia is partly responsible for the hyperglycemia in di...

see more →

Clinicaltrials.gov  167 results

A review of the Efficacy and Cardiovascular Safety of Amylin Analogues.
https://doi.org/10.2174/1574886315999201105153852
Current Drug Safety; Koshy RM, Fernandez CJ et. al.

Nov 6th, 2020 - A large proportion of persons with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) do not reach the glycosylated haemoglobin (HbA1c) target of < 7% (53 mmol/mol) with an increasing proportion of them being overweight or obese. ...

Pseudo-hyperglucagonemia was observed in pancreatectomized patients when measured by gl...
https://doi.org/10.1111/jdi.13325
Journal of Diabetes Investigation References; Kobayashi M, Waki H et. al.

Jun 17th, 2020 - Glucagon is detected in plasma even after total pancreatectomy, and it is debated whether this glucagon is derived from the gastrointestinal tract. Here, we applied sandwich enzyme-linked immunosorbent assay (ELISA) and liquid chromatography-high-...

Effect of short-term intensive insulin therapy on α-cell function in patients with newl...
https://doi.org/10.1097/MD.0000000000019685
Medicine Zheng HL, Xing Y et. al.

Apr 3rd, 2020 - The effect of intensive insulin therapy on hyperglucagonemia in newly diagnosed type 2 diabetes (T2DM), and its associations with β-cell function, has not been elucidated. This study assessed the effect of 12 weeks of intensive insulin therapy on ...

Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic ...
https://doi.org/10.2337/db19-0715
Diabetes Suppli MP, Bagger JI et. al.

Jan 24th, 2020 - Glucagon secretion is regulated by circulating glucose, but it has turned out that amino acids also play an important role and that hepatic amino acid metabolism and glucagon are linked in a mutual feedback cycle, the liver-α-cell axis. On the bas...

A Primary Role for α-Cells as Amino Acid Sensors.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085241
Diabetes Dean ED

Oct 27th, 2019 - Glucagon and its partner insulin are dually linked in both their secretion from islet cells and their action in the liver. Glucagon signaling increases hepatic glucose output, and hyperglucagonemia is partly responsible for the hyperglycemia in di...

see more →

News  1 results

Multiple Metabolic Abnormalities Seen in Lupus
https://www.medpagetoday.com/rheumatology/lupus/64321

Apr 4th, 2017 - Action Points Note that this meal-tolerance study suggested that patients with mild or inactive lupus had greater indices of insulin resistance than healthy controls. Be aware that the small sample size precluded final adjustment for potential con...

see more →