About 1,845 results

ALLMedicine™ Hypopituitarism Center

Research & Reviews  681 results

Apoplexy in a previously undiagnosed pituitary macroadenoma in the setting of recent CO...
BMJ Case Reports; Liew SY, Seese R et. al.

Jul 30th, 2021 - Pituitary apoplexy is an endocrine emergency, which commonly presents as hypopituitarism. Prompt diagnosis and treatment can be both life and vision saving. There are a growing number of published case reports postulating a link between COVID-19 a...

Sexual dysfunctions in Sheehan's syndrome.
Endocrine Practice : Official Journal of the American Col... Mandal S, Mukhopadhyay P et. al.

Jul 27th, 2021 - Sheehan's syndrome (SS) is not an uncommon cause of hypopituitarism in developing countries. Lack of sex-steroids both from ovaries and adrenals could lead to sexual dysfunction in SS. Sexual function is a neglected aspect of health in women in de...

Retracing the tracks for SIAD: hyponatraemia due to post-traumatic brain injury hypopit...
BMJ Case Reports; Awan NM, Mat A et. al.

Jul 22nd, 2021 - Hyponatraemia is common in hospital practice, with the syndrome of inappropriate antidiuresis (SIAD) being the most common underlying aetiology. A relatively less frequent but important cause is adrenal insufficiency (AI). We describe the case of ...

High-throughput splicing assays identify missense and silent splice-disruptive POU1F1 v...
American Journal of Human Genetics; Gergics P, Smith C et. al.

Jul 17th, 2021 - Pituitary hormone deficiency occurs in ∼1:4,000 live births. Approximately 3% of the cases are due to mutations in the alpha isoform of POU1F1, a pituitary-specific transcriptional activator. We found four separate heterozygous missense variants i...

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Guidelines  5 results

Management of immune-related adverse events in endocrine organs induced by immune check...
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practi...
The Journal of Clinical Endocrinology and Metabolism; Fleseriu M, Hashim IA et. al.

Nov 5th, 2016 - To formulate clinical practice guidelines for hormonal replacement in hypopituitarism in adults. The participants include an Endocrine Society-appointed Task Force of six experts, a methodologist, and a medical writer. The American Association for...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for Pr...
Neurosurgery Fleseriu M, Bodach ME et. al.

Sep 17th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present with hypopituitarism and/or hyperprolactinemia. To review the existing literature as it pertains to preoperative endocrine assessment in the work...

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Pri...
Neurosurgery Lucas JW, Bodach ME et. al.

Sep 17th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present clinically with vision loss and hypopituitarism. To characterize the existing literature as it pertains to the initial management of NFPAs. A sys...

Pituitary incidentaloma: an endocrine society clinical practice guideline.
The Journal of Clinical Endocrinology and Metabolism; Freda PU, Beckers AM et. al.

Apr 9th, 2011 - The aim was to formulate practice guidelines for endocrine evaluation and treatment of pituitary incidentalomas. Consensus was guided by systematic reviews of evidence and discussions through a series of conference calls and e-mails and one in-per...

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Drugs  1 results see all →

Clinicaltrials.gov  12 results

Next Day Growth Hormone Predicting Pituitary Function After Adenomectomy

Oct 17th, 2018 - Transsphenoidal adenomectomy usually accompanied by the failure or recovery of the pituitary gland, which usually causing further hypopituitarism and hormone recovery. In order to prevent the potential applications of adrenal cortical malfunction ...

The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic Hypopituitarism

Oct 9th, 2018 - Background The investigators and others have shown that long-term hydrocortisone replacement therapy at higher doses of hydrocortisone replacement therapy at higher doses of hydrocortisone replacement (as previously recommended) is associated with...

Treatment of Adrenal Insufficiency in Children

May 19th, 2017 - This is a Phase 3, open label, single centre study of Infacort® in neonates, infants and children less than 6 years of age with adrenal insufficiency. The study will be conducted in a total of 24 subjects, before their 6th birthday, requiring repl...

Baseline Sexual Function, Cognitive Function, Body Composition and Muscle Parameters and Pharmacokinetics of Transdermal Testosterone Gel in Women With Hypopituitarism

Apr 18th, 2017 - The ovaries and the adrenal glands contribute to the daily production of 300 micrograms of testosterone in healthy, menstruating women. The physiologic role of testosterone in women, however, remains poorly understood. Previous studies of testoste...

Androgen Replacement Therapy in Women With Hypopituitarism

Mar 25th, 2015 - Patients will be randomized into 2 groups to receive testosterone replacement therapy or placebo. Group 1 will receive 2 testosterone patches and estrogen pills for 12 months. Group 2 will receive 2 placebo patches and estrogen pills for 12 months...

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News  33 results

Patients on Steroids With COVID-19 Might Need Rescue Steroids

Apr 3rd, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. Endocrinologists have underlined the importance that physicians consider "a stress dose" of glucocorticoids in the event of severe COVID-19 infec...

Chronic blistering rash on hands
MDedge Family Medicine;

Nov 7th, 2019 - Pseudoporphyria has a similar presentation to PCT but with no abnormalities in porphyrin metabolism. Risk factors include UV radiation exposure; use of medications such as nonsteroidal anti-inflammatory drugs, diuretics, and retinoids; chronic ren.

Pituitary Hormones Should Be 'Restored to Healthy Levels'

Oct 20th, 2016 - Patients with hypopituitarism should have their hormone levels restored as close to physiologic levels as possible, while taking into account potential interactions between hormones and other medications, say new guidelines on diagnosing and manag...

Fast Five Quiz: How Much Do You Know About Depression?

Jan 20th, 2016 - Neuroimaging can help clarify the nature of the neurologic illness that may produce psychiatric symptoms, but these studies are costly and may be of questionable value in patients without discrete neurologic deficits. CT scanning or MRI of the bra...

AACE: Endocrine treatment of childhood cancer survivors needs improvement
Deepak Chitnis

Jun 2nd, 2015 - NASHVILLE – Endocrinologists dealing with adult patients who survived cancer during childhood should ensure that they have an adequate understanding of the elevated risk that such patients are at for various endocrine conditions, such as hypogonad.

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Patient Education  6 results see all →