ALLMedicine™ Metabolic Acidosis Center

Sep 16th, 2020 - An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas showed a marked metabolic acidosis with a high anion gap. Lactate and ket...

Sep 14th, 2020 - Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is known abo...

Sep 13th, 2020 - Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of CKD but associated concerns center on administering sodium to patients with hypertension and sodium-retentive states. Veverimer (formerly TRC101) is a novel, non-absorbable ...

Sep 9th, 2020 - To help shape the design of a future double blind placebo-controlled randomised clinical trial of bicarbonate therapy for metabolic acidosis, based on opinions of intensive care clinicians in Australia and New Zealand. An online survey was designe...

Sep 8th, 2020 - The risk factors for peri-intubation cardiac arrest in critically ill children are incompletely understood. The study objective was to derive physiologic risk factors for deterioration during tracheal intubation in a pediatric emergency department...

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hyp...

Jun 12th, 2018 - Metabolic acidosis is commonly found in patients with chronic kidney disease (CKD), and its causes are: impaired ammonia excretion, reduced tubular bicarbonate reabsorption and insufficient renal bicarbonate production in relation to the amount of...

Feb 1st, 2016 - A panel of internists and nephrologists developed this practical approach for the Kidney Disease Outcomes Quality Initiative to guide assessment and care of chronic kidney disease (CKD) by primary care clinicians. Chronic kidney disease is defined...

May 23rd, 2013 - Protein energy wasting (PEW) is common in patients with chronic kidney disease (CKD) and is associated with adverse clinical outcomes, especially in individuals receiving maintenance dialysis therapy. A multitude of factors can affect the nutritio...

Sep 16th, 2020 - An 84-year-old woman presented in extremis with confusion and Kussmaul respiration. She had a history of urosepsis, renal impairment and osteoarthrosis. The venous blood gas showed a marked metabolic acidosis with a high anion gap. Lactate and ket...

Sep 14th, 2020 - Diabetic ketoacidosis (DKA) is a medical emergency with a high mortality rate and is associated with severe metabolic acidosis and dehydration. DKA patients have an increased risk of arterial and venous thromboembolism, however little is known abo...

Sep 13th, 2020 - Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of CKD but associated concerns center on administering sodium to patients with hypertension and sodium-retentive states. Veverimer (formerly TRC101) is a novel, non-absorbable ...

Sep 9th, 2020 - To help shape the design of a future double blind placebo-controlled randomised clinical trial of bicarbonate therapy for metabolic acidosis, based on opinions of intensive care clinicians in Australia and New Zealand. An online survey was designe...

Sep 8th, 2020 - The risk factors for peri-intubation cardiac arrest in critically ill children are incompletely understood. The study objective was to derive physiologic risk factors for deterioration during tracheal intubation in a pediatric emergency department...

Jun 27th, 2019 - The investigational drug veverimer was safe and effective for treating patients with metabolic acidosis from chronic kidney disease, according to phase III data. In a 40-week extension study, only 2% of those on veverimer had serious adverse event...

Dec 12th, 2018 - Patients with moderate ulcerative colitis may benefit from cannabis, according to a new study that reported a decrease in disease activity index in patients who used the drug. A recent analysis found that consuming probiotics may contribute to sma...

Nov 17th, 2018 - Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hyp...

Feb 14th, 2018 - Question: Paramedics brought an unconscious 70-year-old man to a Florida hospital emergency department. The patient had the words “Do Not Resuscitate” tattooed onto his chest.

Mar 1st, 2017 - In the article “ A patient with altered mental status and an acid-base disturbance ” (Mani S, Rutecki GW, Cleve Clin J Med 2017; 84:27–34), 2 errors occurred in Table 2. The corrected table appears with corrections shown in red: In addition, two s.