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About 125 results

ALLMedicine™ Acute Hypoglycemia Center

Research & Reviews  47 results

Somatostatin Receptor Antagonism Reverses Glucagon Counterregulatory Failure in Recurre...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482965
Endocrinology Hoffman EG, Jahangiriesmaili M et. al.

Sep 4th, 2021 - Recent antecedent hypoglycemia is a known source of defective glucose counter-regulation in diabetes; the mechanisms perpetuating the cycle of progressive α-cell failure and recurrent hypoglycemia remain unknown. Somatostatin has been shown to sup...

Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8345897
European Journal of Endocrinology; Andersen A, Bagger JI et. al.

Jun 5th, 2021 - Hypoglycemia is associated with an increased risk of cardiovascular disease including cardiac arrhythmias. We investigated the effect of hypoglycemia in the setting of acute glycemic fluctuations on cardiac rhythm and cardiac repolarization in ins...

Interleukin-6 response to insulin-induced hypoglycemia is associated with hypothalamic-...
https://doi.org/10.1016/j.jneuroim.2020.577446
Journal of Neuroimmunology; Drummond JB, Soares BS et. al.

Nov 24th, 2020 - Increased plasma levels of interleukin-6 (IL-6) in response to acute hypoglycemia have been well documented. Aiming to study the interaction between IL-6 and counter-regulatory hormones during hypoglycemic stress we conducted an exploratory single...

Dual self-regulated delivery of insulin and glucagon by a hybrid patch.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7703584
Proceedings of the National Academy of Sciences of the Un... Wang Z, Wang J et. al.

Nov 13th, 2020 - Reduced β-cell function and insulin deficiency are hallmarks of diabetes mellitus, which is often accompanied by the malfunction of glucagon-secreting α-cells. While insulin therapy has been developed to treat insulin deficiency, the on-demand sup...

Rapid gastric emptying in diabetes mellitus: Pathophysiology and clinical importance.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7707148
Journal of Diabetes and Its Complications; Goyal RK, Cristofaro V et. al.

Aug 24th, 2019 - Although slow gastric emptying (gastroparesis) is a well-known complication of chronic hyperglycemia in diabetes mellitus (DM), it recently has become clear that rapid gastric emptying also is a frequent and important diabetic complication. In con...

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Clinicaltrials.gov  3 results

Metabolic Consequences of Heterozygous Hereditary Fructose Intolerance
https://clinicaltrials.gov/ct2/show/NCT02979106

Jul 17th, 2019 - Background: High fructose intake increases blood lactate, triglyceride and uric acid concentrations. Uric acid may contribute to insulin resistance and dyslipidemia in the general population. In patients with hereditary fructose intolerance fructo...

The Effect of Intravenous Lactate on Brain Lactate Concentrations During Hypoglycemia
https://clinicaltrials.gov/ct2/show/NCT03286816

Sep 19th, 2017 - Patients with type 1 diabetes (T1DM) who are unable to perceive symptoms of hypoglycemia, referred to as impaired awareness of hypoglycemia (IAH), are at very high risk of severe hypoglycemia. IAH affects approximately 25% of patients with T1DM. B...

Effect of Medium Chain Fatty Acids on Cognitive Function During Acute Hypoglycemia in Patients With Type 1 Diabetes
https://clinicaltrials.gov/ct2/show/NCT00592072

Jan 22nd, 2015 - Twelve subjects between the ages of 18 years and 55 years who have had Type 1 Diabetes Mellitus for more than five years and have had tight control of their diabetes as determined by screening blood work will be invited to participate. Each study ...

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