ALLMedicine™ Acute Lactic Acidosis Center

Oct 18th, 2022 - Pearson syndrome (PS) is a rare fatal mitochondrial disorder caused by single large-scale mitochondrial DNA deletions (SLSMDs). Most patients present with anemia in infancy. Bone marrow cytology with vacuolization in erythroid and myeloid precurso...

Jun 14th, 2016 - Mortality rates associated with severe lactic acidosis (blood pH<7.2) due to sepsis or low-flow states are high. Eliminating the triggering conditions remains the most effective therapy. Although recommended by some, administration of sodium bicar...

Jan 17th, 2015 - Thiamine is a water-soluble vitamin implicated in several metabolic processes. Its deficiency, due to prolonged parenteral nutrition without adequate vitamin supplementation, can lead to multiorgan failure characterized by cardiovascular impairmen...

Jan 15th, 2014 - Lactic acidosis is a rare and potentially lethal complication of metformin therapy. We present a case of a middle-aged diabetic man with metformin-induced acute lactic acidosis successfully managed with timely hemodialysis.

Sep 5th, 2012 - Acute metabolic acidosis is associated with increased morbidity and mortality because of its depressive effects on cardiovascular function, facilitation of cardiac arrhythmias, stimulation of inflammation, suppression of the immune response, and o...

Jun 8th, 2005 - Action Points Cardiotoxicity is a well-recognized side effect of Adriamycin treatment, but typically heart failure develops over time and is dose dependent. Advanced age is an important risk factor. This case report suggests that Adriamycin may al...

Abstract and Introduction Abstract Mortality rates associated with severe lactic acidosis (blood pH < 7.2) due to sepsis or low-flow states are high. Eliminating the triggering conditions remains the most effective therapy. Although recommended by...

Abstract and Introduction Abstract Mortality rates associated with severe lactic acidosis (blood pH < 7.2) due to sepsis or low-flow states are high. Eliminating the triggering conditions remains the most effective therapy. Although recommended by...