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About 668 results

ALLMedicine™ Adrenal Crisis Center

Research & Reviews  213 results

Isolated ACTH deficiency following immunization with the BNT162b2 SARS-CoV-2 vaccine: a...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297640
BMC Endocrine Disorders; Morita S, Tsuji T et. al.

Jul 20th, 2022 - The global COVID-19 pandemic requires urgent development of new vaccines. Endocrinological adverse effects following the new mRNA vaccine against COVID-19 have been reported in several cases. Specific to the involvement of pituitary function; howe...

Adrenal insufficiency in pregnancy: Physiology, diagnosis, management and areas for fut...
https://doi.org/10.1007/s11154-022-09745-6
Reviews in Endocrine & Metabolic Disorders; Lee JH, Torpy DJ

Jul 12th, 2022 - Adrenal insufficiency requires prompt diagnosis in pregnancy, as untreated, it can lead to serious consequences such as adrenal crisis, intrauterine growth restriction and even foetal demise. Similarities between symptoms of adrenal insufficiency ...

Adrenal insufficiency among children treated with hormonal therapy for infantile spasms.
https://doi.org/10.1111/epi.17348
Epilepsia Doré-Brabant G, Laflamme G et. al.

Jun 28th, 2022 - Hormonal therapy is a standard treatment for children with infantile spasms. However, the high doses given and long treatment duration expose patients to the risk of adrenal insufficiency (AI). This study aims to quantify the cumulative incidence ...

Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
https://clinicaltrials.gov/ct2/show/NCT05435781

Jun 28th, 2022 - The study will include patients with PMR/GCA on ongoing prednisolone treatment in a low dose of > 0 mg/day and ≤5mg/day. Eligible patients will undergo a Synacthen® test and 250 patients with a stimulated cortisol level <420 nmol/l (biochemical ad...

Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226983
Journal for Immunotherapy of Cancer; Rouhani SJ, Yu J et. al.

Jun 23rd, 2022 - Patients with cancer were excluded from phase 3 COVID-19 vaccine trials, and the immunogenicity and side effect profiles of these vaccines in this population is not well understood. Patients with cancer can be immunocompromised from chemotherapy, ...

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Guidelines  2 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

Consensus statement on the diagnosis, treatment and follow-up of patients with primary ...
https://doi.org/10.1111/joim.12162
Journal of Internal Medicine; Husebye ES, Allolio B et. al.

Dec 18th, 2013 - Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex. Consequently, patients with PAI are at higher risk of de...

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Clinicaltrials.gov  13 results

Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
https://clinicaltrials.gov/ct2/show/NCT05435781

Jun 28th, 2022 - The study will include patients with PMR/GCA on ongoing prednisolone treatment in a low dose of > 0 mg/day and ≤5mg/day. Eligible patients will undergo a Synacthen® test and 250 patients with a stimulated cortisol level <420 nmol/l (biochemical ad...

Predisposing Factors for the Incidence of Adrenal Crisis
https://clinicaltrials.gov/ct2/show/NCT03410160

Oct 14th, 2019 - Patients with chronic adrenal insufficiency (AI) are at risk of suffering from life-threatening adrenal crisis (AC), despite established hormone replacement therapies and patient education. Recent retrospective analyses observed different risk fac...

Rheumatoid Arthritis Adrenal Recovery Study
https://clinicaltrials.gov/ct2/show/NCT03294876

Oct 11th, 2018 - Cortisol is a naturally occurring stress hormone. It is made by the adrenal glands in response to hormones produced by the pituitary and hypothalamus. Man-made forms of cortisol ('steroids', for example prednisolone) have been used for the treatme...

Study to Investigate Adrenal Crisis (Six-year Follow-up)
https://clinicaltrials.gov/ct2/show/NCT03499990

Apr 18th, 2018 - Despite established hormone replacement therapy, patients with chronic adrenal insufficiency are at risk of suffering from life threatening adrenal crisis with a considerable mortality. A former prospective study revealed a frequency of about 8 ad...

Management of Adrenal Emergency in Germany
https://clinicaltrials.gov/ct2/show/NCT03426332

Feb 8th, 2018 - Despite established hormone replacement therapy, patients with chronic adrenal insufficiency (AI) are at risk of suffering from adrenal crisis (AC). Further data suggests that the management of AC is often problematic and the time to adequate trea...

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News  37 results

Opioid-Induced Adrenal Insufficiency for the Hospitalist
https://www.medscape.com/viewarticle/961663

Oct 27th, 2021 - Case A 60-year-old woman with metastatic breast cancer using morphine extended release 30 mg twice daily and as-needed oxycodone for cancer-related pain presents with fever, dyspnea, and productive cough for 2 days. She also notes several weeks of...

Immunotherapy Transforms Melanoma Care, But Challenges Remain
https://www.onclive.com/view/immunotherapy-transforms-melanoma-care-but-challenges-remain

Oct 6th, 2021 - Norman E. Sharpless, MD Today, the field of melanoma is virtually unrecognizable from what it was not that long ago, says Norman E. Sharpless, MD. Most of us are old enough to remember a time when there was nothing going on in melanoma, said Sha...

Drug Safety Update on Hydrocortisone Granules in Young Children
https://www.medscape.com/viewarticle/946284

Feb 23rd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

Practical Advice for Immunotherapy Era Emerges From ASCO
https://www.onclive.com/view/practical-advice-for-immunotherapy-era-emerges-from-asco

Dec 20th, 2020 - Jedd D. Wolchok, MD, PhD Three years ago, Jedd D. Wolchok, MD, PhD, sat in the lobby of a Chicago hotel at midnight during the ASCO annual meeting with several of his colleagues and sketched out on a napkin a dream trial that would simultaneously...

New adventures of an old device: Clinic delivers cortisol via the insulin pump
https://www.mdedge.com/endocrinology/article/200246/pituitary-thyroid-adrenal-disorders/new-adventures-old-device-clinic
Randy Dotinga

May 6th, 2019 - LOS ANGELES – The venerable insulin pump is being repurposed: A Detroit-area endocrinology team reports successfully using insulin pumps to deliver hydrocortisone to patients with adrenal insufficiency who have fared poorly on oral medications. “W.

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Patient Education  2 results see all →