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ALLMedicine™ Adrenal Crisis Center

Research & Reviews  168 results

Addison Disease
https://emedicine.medscape.com/article/116467-overview

Jan 13th, 2022 - Practice Essentials Addison disease (or Addison's disease) is adrenocortical insufficiency due to the destruction or dysfunction of the entire adrenal cortex. It affects glucocorticoid and mineralocorticoid function. The onset of disease usually o...

Adrenal Crisis
http://emedicine.medscape.com/article/116716-overview

Jan 13th, 2022 - Practice Essentials Do not confuse acute adrenal crisis with Addison disease. In 1855, Thomas Addison described a syndrome of long-term adrenal insufficiency that develops over months to years, with weakness, fatigue, anorexia, weight loss, and hy...

Adrenal Insufficiency at the Time of COVID-19: A Retrospective Study in Patients Referr...
https://doi.org/10.1210/clinem/dgaa793
The Journal of Clinical Endocrinology and Metabolism; Carosi G, Morelli V et. al.

Dec 22nd, 2021 - Coronavirus disease 2019 (COVID-19) represents a global health emergency, and infected patients with chronic diseases often present with a severe impairment. Adrenal insufficiency (AI) is supposed to be associated with an increased infection risk,...

An autopsy case of unexpected death due to Addison's disease caused by adrenal tubercul...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8642993
European Journal of Medical Research; Zhao N, Gao Y et. al.

Dec 6th, 2021 - Adrenal tuberculosis is difficult to diagnose due to non-specific symptom. Unexpected death due to adrenal insufficiency after trauma surgery is rare. A 45-year-old man, who was admitted to hospital because of trauma to the right hand, died unexpe...

Adrenal Crisis Presenting as Recurrent Encephalopathy Mimicking Autoimmune, Infectious ...
https://doi.org/10.1097/NRL.0000000000000374
The Neurologist; Poon JT, Salzman K et. al.

Dec 3rd, 2021 - Adrenal crisis can present with life-threatening complications and mimic autoimmune or infectious encephalitis, and common variable immune deficiency (CVID). The literature regarding the neurological complications of adrenal crisis is limited and ...

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Guidelines  1 results

Management of immune-related adverse events in endocrine organs induced by immune check...
https://doi.org/10.1507/endocrj.EJ19-0163
Endocrine Journal; Arima H, Iwama S et. al.

Jun 28th, 2019 - Immune checkpoint inhibitors (ICIs) have become a promising treatment for advanced malignancies. However, these drugs can induce immune-related adverse events (irAEs) in several organs, including skin, gastrointestinal tract, liver, muscle, nerve,...

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Clinicaltrials.gov  5 results

Predisposing Factors for the Incidence of Adrenal Crisis
https://clinicaltrials.gov/ct2/show/NCT03410160

Oct 14th, 2019 - Patients with chronic adrenal insufficiency (AI) are at risk of suffering from life-threatening adrenal crisis (AC), despite established hormone replacement therapies and patient education. Recent retrospective analyses observed different risk fac...

Rheumatoid Arthritis Adrenal Recovery Study
https://clinicaltrials.gov/ct2/show/NCT03294876

Oct 11th, 2018 - Cortisol is a naturally occurring stress hormone. It is made by the adrenal glands in response to hormones produced by the pituitary and hypothalamus. Man-made forms of cortisol ('steroids', for example prednisolone) have been used for the treatme...

Continuous Subcutaneous Hydrocortisone Infusion In Addison's Disease and Type 1 Diabetes
https://clinicaltrials.gov/ct2/show/NCT01840189

Feb 1st, 2017 - Treatment of Addison's disease includes glucocorticoid and mineralocorticoid replacement. Despite optimized therapy with these steroids, many patients suffer from impaired quality of life and increased mortality. The etiology of the premature deat...

Pharmacokinetics of Hydrocortisone After Subcutaneous Administration in Chronic Adrenal Insufficiency
https://clinicaltrials.gov/ct2/show/NCT01450930

Aug 1st, 2012 - Patients with chronic adrenal insufficiency need to adapt their hydrocortisone replacement dose in conditions of physical or psychological stress to prevent life threatening adrenal crisis. In cases of more severe impairment or unsecure gastrointe...

Survey in Patients With Chronic Adrenal Insufficiency in Germany
https://clinicaltrials.gov/ct2/show/NCT00444119

Mar 7th, 2007 - The purpose of this survey is to assess patients with chronic primary or secondary adrenal failure regarding subjective health status, incidence and causes of adrenal crisis, hormone replacement regimens and concomitant endocrine or non endocrine ...

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News  32 results

Opioid-Induced Adrenal Insufficiency for the Hospitalist
https://www.medscape.com/viewarticle/961663

Oct 27th, 2021 - Case A 60-year-old woman with metastatic breast cancer using morphine extended release 30 mg twice daily and as-needed oxycodone for cancer-related pain presents with fever, dyspnea, and productive cough for 2 days. She also notes several weeks of...

Drug Safety Update on Hydrocortisone Granules in Young Children
https://www.medscape.com/viewarticle/946284

Feb 23rd, 2021 - The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a drug safety update on Alkindi (hydrocortisone granules, Diurnal), after a report of severe adrenal insufficiency in an infant who was switched from hydrocortisone soluble ...

Endocrinopathies: The New Price of Cancer Treatment
https://www.staging.medscape.com/viewarticle/910969

Mar 29th, 2019 - Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block checkpoints—namely cytotoxic T lymphocyte antigen 4 (CTLA-4), programmed cell death protein 1 (PD-1), and programmed cell death protein-ligand 1 (PD-L1)—thus leading to de-re...

Endocrinopathies: The New Price of Cancer Treatment
https://www.medscape.com/viewarticle/910969

Mar 29th, 2019 - Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that block checkpoints—namely cytotoxic T lymphocyte antigen 4 (CTLA-4), programmed cell death protein 1 (PD-1), and programmed cell death protein-ligand 1 (PD-L1)—thus leading to de-re...

AS After GC Common, Persistent in Children With Rheumatic Disease
https://www.medpagetoday.com/rheumatology/arthritis/60986

Oct 24th, 2016 - Action Points Adrenal suppression (AS) following glucocorticoid (GC) therapy in children with rheumatic diseases is common and persistent. Note that some individuals with AS can experience biochemical changes without exhibiting symptoms, leading t...

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Patient Education  2 results see all →