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ALLMedicine™ Diabetes Insipidus Center

Research & Reviews  889 results

Congenital nephrogenic diabetes insipidus presenting as osmotic demyelination syndrome ...
Medicine Kobayashi S, Mizuno N et. al.

Jan 22nd, 2022 - Almost 90% of congenital nephrogenic diabetes insipidus (NDI) cases are caused by mutations in the arginine vasopressin receptor 2 gene, which has X-linked recessive inheritance. Although NDI is commonly diagnosed in early infancy based on its cha...

Diabetes Insipidus

Jan 20th, 2022 - Practice Essentials Diabetes insipidus (DI) is defined as the passage of large volumes (>3 L/24 hr) of dilute urine (< 300 mOsm/kg). It has the following 2 major forms: Central (neurogenic, pituitary, or neurohypophyseal) DI, characterized by decr...

Diabetes Insipidus

Jan 20th, 2022 - Practice Essentials Diabetes insipidus (DI) is defined as the passage of large volumes (>3 L/24 hr) of dilute urine (< 300 mOsm/kg). It has the following 2 major forms: Central (neurogenic, pituitary, or neurohypophyseal) DI, characterized by decr...

Diabetes Insipidus Workup

Jan 20th, 2022 - Approach Considerations In a patient whose clinical presentation suggests diabetes insipidus (DI), laboratory tests must be performed to confirm the diagnosis. A 24-hour urine collection for determination of urine volume is required. In addition, ...

Diabetes Insipidus Treatment & Management

Jan 20th, 2022 - Approach Considerations Fluid replacement Most patients with diabetes insipidus (DI) can drink enough fluid to replace their urine losses. When oral intake is inadequate and hypernatremia is present, replace losses with dextrose and water or an in...

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Guidelines  1 results

ENDOCRINOLOGY IN THE TIME OF COVID-19-2021 UPDATES: The management of diabetes insipidu...
European Journal of Endocrinology; Christ-Crain M, Hoorn EJ et. al.

Jul 23rd, 2021 - COVID-19 has changed the nature of medical consultations, emphasizing virtual patient counselling, with relevance for patients with diabetes insipidus (DI) or hyponatraemia. The main complication of desmopressin treatment in DI is dilutional hypon...

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Drugs  38 results see all →

Clinicaltrials.gov  18 results

PB to Treat Hereditary Nephrogenic Diabetes Insipidus, ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration

Jan 13th, 2022 - The purpose of this research is to study the effectiveness and safety of the medication PB in slowing the frequent urination related to tolvaptan as long-term treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD), or frequent urination...

Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome

Dec 9th, 2021 - Open label, phase II study non randomized single group assignment of 20 evaluable patients 13 years and older, over 37,5 kg body-weight, with sensorineural hearing loss of at least 20 dB at 8 kHz in high frequency average (HFA), AND with documente...

Effects of Intranasal Oxytocin in Patients With Central Diabetes Insipidus

Dec 7th, 2021 - This is a randomized, double-blind, placebo-controlled crossover pilot study of single-dose intranasal oxytocin (4 IU and 24 IU) in 18-60-year-old men and women with central diabetes insipidus to evaluate the effect of oxytocin on anxiety, depress...

AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium

Nov 19th, 2021 - Patients will be referred to the nephrology or the renal physiology department for the usual follow-up of the lithium treatment. After verification of eligilibity criteria, information and collection of consent, patient will be randomized. During ...

Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study

Apr 28th, 2021 - The differential diagnosis of central diabetes insipidus (cDI) is difficult and the current test with the highest diagnostic accuracy is copeptin measurement after hypertonic saline infusion (HIS). Although the HIS improved diagnostic accuracy com...

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News  33 results

Weight Gain Common in Childhood Brain Tumor Survivors

Mar 12th, 2021 - Children who have been treated for brain tumors often experience significant weight gain, and new findings suggest that this could be a sign of hypothalamic-pituitary (HP) dysfunction. "We believe that endocrine surveillance should be initiated ea...

Fast Five Quiz: Unusual Breast Cancer Presentations

Mar 26th, 2020 - Answer 2/5 Which of the following signs and symptoms is most suggestive of pituitary metastasis in patients with a history of breast cancer? Your peers chose: Neurocognitive impairment with headache 0% Worsening of an existing seizure disorder and...

A 6-Year-Old Boy With Fever and Bone Swelling: Osmosis USMLE Study Question

Mar 6th, 2020 - Langerhans cell histiocytosis (LCH) is a neoproliferative disorder of Langerhans cells, the dendritic cells of the skin the mucosa. It often involves osteolytic bone lesions and invasion of multiple organs. There are tennis racket-shaped inclusion...

Hemorrhagic Crusted Papule on the Arm
Somya Abubucker, MD, Jonathan Cuda, MD et. al.

Oct 31st, 2018 - The Diagnosis: Self-healing Langerhans Cell Histiocytosis Histopathologic examination showed an infiltrate of mononuclear cells with indented nuclei admixed with a variable dermal inflammatory infiltrate. Immunohistochemistry demonstrated cells th.

Copeptin Test Can Detect Diabetes Insipidus vs Other Polyuria

Aug 9th, 2018 - A blood test for copeptin, a precursor of antidiuretic hormone (ADH, vasopressin), differentiates between "harmless" polydipsia-polyuria and diabetes insipidus more quickly and accurately than a traditional water-deprivation test, researchers repo...

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Patient Education  3 results see all →