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About 3,033 results

ALLMedicine™ Growth Hormone Deficiency Center

Research & Reviews  956 results

Genetic Causes of Growth Disorders
https://clinicaltrials.gov/ct2/show/NCT02311322

Sep 28th, 2022 - Children often present to pediatricians and pediatric endocrinologists because of abnormal body growth, including both childhood growth failure and, less commonly, overgrowth. Sometimes the cause is evident, for example, growth hormone deficiency ...

Endocrine complications after hematopoietic stem cell transplantation during childhood ...
https://doi.org/10.1111/cen.14826
Clinical Endocrinology; Figueiredo AA, Cavaco D et. al.

Sep 27th, 2022 - Hematopoietic stem cell transplantation (HSCT) is a therapeutic option in numerous hematologic diseases and solid tumours. Increasing indications for HSCT and reduction in associated mortality have been raising the number of paediatric HSCT surviv...

Bone health in adults with Prader-Willi syndrome: clinical recommendations based on a m...
https://doi.org/10.1210/clinem/dgac556
The Journal of Clinical Endocrinology and Metabolism; van Abswoude DH, Pellikaan K et. al.

Sep 24th, 2022 - Prader-Willi syndrome (PWS) is a rare complex genetic syndrome, characterized by delayed psychomotor development, hypotonia and hyperphagia. Hormone deficiencies like hypogonadism, hypothyroidism and growth hormone deficiency are common. The combi...

Pediatric Craniopharyngioma: The Impact of Visual Deficits and Hormone Deficiencies on ...
https://doi.org/10.1016/j.ijrobp.2022.09.061
International Journal of Radiation Oncology, Biology, Phy... Merchant TE, Dangda S et. al.

Sep 22nd, 2022 - . Pediatric patients diagnosed with craniopharyngioma risk cognitive deficits when treated with radiation therapy. We investigated cognitive outcomes after conformal photon radiation therapy (CRT), the impact of visual deficits, and hormone defici...

Identification of a novel MAP3K1 variant in a family with 46, XY DSD and partial growth...
https://doi.org/10.3892/mmr.2022.12854
Molecular Medicine Reports; Cheng Y, Xu C et. al.

Sep 15th, 2022 - The 46, XY disorder of sex development (DSD) is the main cause of birth defects; however, as it is a group of highly heterogeneous diseases, >50% of cases are not accurately diagnosed. Identification of more cases will improve understanding of the...

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Guidelines  1 results

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline for Pr...
https://doi.org/10.1227/NEU.0000000000001387
Neurosurgery Fleseriu M, Bodach ME et. al.

Sep 17th, 2016 - Nonfunctioning pituitary adenomas (NFPAs) are among the most common pituitary lesions and may present with hypopituitarism and/or hyperprolactinemia. To review the existing literature as it pertains to preoperative endocrine assessment in the work...

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Drugs  14 results see all →

Clinicaltrials.gov  165 results

Genetic Causes of Growth Disorders
https://clinicaltrials.gov/ct2/show/NCT02311322

Sep 28th, 2022 - Children often present to pediatricians and pediatric endocrinologists because of abnormal body growth, including both childhood growth failure and, less commonly, overgrowth. Sometimes the cause is evident, for example, growth hormone deficiency ...

A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT05171855

Sep 2nd, 2022 - This is a phase 3 open-label multicenter extension study designed to evaluate the long-term safety and efficacy of Lonapegsomatropin administered once-weekly. The study participants are adults (males and females) with confirmed growth hormone defi...

Phase 2 Study of LUM-201 in Children With Growth Hormone Deficiency (OraGrowtH210 Trial)
https://clinicaltrials.gov/ct2/show/NCT04614337

Sep 2nd, 2022 - This trial will have one screening visit with tests to assess if subjects are eligible to start study therapy. Once subjects have completed screening, and if they are determined to be eligible, they will be randomized to receive one of three oral ...

A Phase 3, Multicenter Study To Evaluate The Efficacy And Safety Of MOD-4023 In Adults With Growth Hormone Deficiency
https://clinicaltrials.gov/ct2/show/NCT01909479

Aug 12th, 2022 - This will be a randomized, double-blind, placebo-controlled, parallel-group, multicenter study in adult subjects with GHD to assess the safety and efficacy of a long-acting, once weekly injection of modified hGH (MOD-4023).

Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD
https://clinicaltrials.gov/ct2/show/NCT02988687

Aug 4th, 2022 - Growth hormone replacement has consistently shown improvements in body composition, exercise capacity, endothelial function, inflammatory biomarkers, bone mineral density, lipoprotein metabolism, and self-reported quality of Life (QOL) in patients...

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News  76 results

FDA Approves First Once-Weekly Growth Hormone for Children
https://www.medscape.com/viewarticle/958043

Sep 2nd, 2021 - The US Food and Drug Administration (FDA) has approved lonapegsomatropin (Skytrofa, Ascendis Pharma), the first weekly subcutaneous injectable growth hormone for children with growth hormone deficiency (GHD). The approval was based on the findings...

More Promising Tirzepatide Data; Continuous Glucose Monitoring Wins in Diabetes
https://www.medpagetoday.com/endocrinology/generalendocrinology/92929

Jun 6th, 2021 - The investigational dual GIP and GLP-1 receptor agonist tirzepatide significantly reduced HbA1c levels and induced weight loss in patients with type 2 diabetes compared with insulin glargine in the SURPASS-4 trial, Eli Lilly announced. A randomize...

Weight Gain Common in Childhood Brain Tumor Survivors
https://www.medscape.com/viewarticle/947349

Mar 12th, 2021 - Children who have been treated for brain tumors often experience significant weight gain, and new findings suggest that this could be a sign of hypothalamic-pituitary (HP) dysfunction. "We believe that endocrine surveillance should be initiated ea...

Childhood growth hormones raise risk for adult cardiovascular events
https://www.mdedge.com/pediatrics/article/234747/endocrinology/childhood-growth-hormones-raise-risk-adult-cardiovascular
Heidi Splete

Jan 19th, 2021 - Childhood treatment with recombinant human growth hormone was associated with a significantly increased risk of cardiovascular events, based on data from more than 3,000 individuals. “Both excess levels of growth hormone and [growth hormone defici.

First-of-Its Kind Guideline on Lipid Monitoring in Endocrine Diseases
https://www.staging.medscape.com/viewarticle/940135

Nov 2nd, 2020 - Endocrine diseases of any type — not just diabetes — can represent a cardiovascular risk and patients with those disorders should be screened for high cholesterol, according to a new clinical practice guideline from the Endocrine Society. "The sim...

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Patient Education  1 results see all →