ALLMedicine™ Hypercalcemia Center

Jan 25th, 2022 - Advanced cancers can have many complications including paraneoplastic processes such as dermatomyositis, hypercalcemia and encephalitis. Due to the wide-ranging nature of symptoms, the diagnosis requires a high index of suspicion and often require...

Jan 19th, 2022 - This real-world study evaluated whether long-term use of eldecalcitol (ELD) increases the risk of adverse events (AEs), namely, hypercalcemia, acute kidney injury (AKI), and urolithiasis, and analyzed the ELD-induced risk of rare AEs such as osteo...

Jan 12th, 2022 - Practice Essentials Cholangiocarcinomas (CCCs) are malignancies of the biliary duct system that may originate in the liver and extrahepatic bile ducts, which terminate at the ampulla of Vater.[1, 2, 3, 4, 5] CCCs are encountered in three anatomic ...

Jan 12th, 2022 - Practice Essentials Cholangiocarcinomas (CCCs) are malignancies of the biliary duct system that may originate in the liver and extrahepatic bile ducts, which terminate at the ampulla of Vater. [1, 2, 3, 4, 5] CCCs are encountered in three anatomic...

Jan 11th, 2022 - Early electrolyte and mineral imbalances have emerged as a conspicuous problem in very preterm babies since the revision of nutrition guidelines and the eventual implementation of early aggressive parenteral nutrition (PN). We opted to carry out a...

Jan 19th, 2019 - Adult T-cell leukemia-lymphoma (ATL) is a distinct mature T-cell malignancy caused by chronic infection with human T-lymphotropic virus type 1 with diverse clinical features and prognosis. ATL remains a challenging disease as a result of its diver...

Feb 12th, 2017 - Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-r...

Oct 12th, 2014 - Hydroelectrolytic disorders are one of the most common metabolic complications in cancer patients. Although often metabolic alterations affecting various ions are part of the manifestations of the oncological disease, even in the form of paraneopl...

Jan 11th, 2022 - Metabolic bone disorders are very common in the general population and include parathyroid disorders like multiple endocrine neoplasia type 1, jaw tumor syndrome, familial hypocalciuric hypercalcemia, parathyroid cancer, osteoporosis and Paget s d...

Dec 16th, 2021 - This prospective cross-sectional study was conducted at the Section of Chemical Pathology, Department of Pathology and Laboratory Medicine, AKUH Karachi Pakistan after approval from Aga Khan University Hospital's Ethics Review Committee (ERC ID: 2...

Oct 21st, 2021 - Parathyroid hormone, released from the parathyroid gland, plays an important role in keeping the ionized calcium in between the reference values in body. Precise control of ionized calcium is particularly necessary to ensure the optimal function o...

Oct 13th, 2021 - Multiple myeloma (MM) is a neoplastic plasma cell disorder that is characterized by osteolytic bone lesions, anemia, hypercalcemia and renal failure. belantamab mafodotin was well tolerated in previous studies with at least one dose of belantamab ...

Sep 14th, 2021 - Idiopathic infantile hypercalcemia (IIH; omim 143880) is a genetic disorder of mineral metabolism characterized by severe hypercalcemia and/or hypercalciuria, suppressed serum levels of parathyroid hormone (PTH) and elevated levels of the active v...

Jan 10th, 2022 - The FDA has granted a fast track designation to enobosarm as a potential therapeutic option for patients with androgen receptor (AR)–positive, estrogen receptor (ER)–positive, HER2-negative, metastatic breast cancer who progressed on a nonsteroida...

Jan 4th, 2022 - Multiple myeloma at a younger age did not portend more aggressive disease or worse outcomes but significantly shortened lifespan as compared with the general population without myeloma, according to one of the largest studies of its kind. Over a 1...

Oct 20th, 2021 - Key clinical point: Bone-modifying agents (BMAs) are overused in the real world in patients with metastatic castration-sensitive prostate cancer (mCSPC). Major finding: Receipt of BMAs was reported in 23.

Oct 4th, 2021 - Background Osteoporosis is characterized by low bone mass, deterioration of bone tissue and architecture, compromised bone strength, and an increase in fracture risk.1 The World Health Organization (WHO) defines osteoporosis as a bone mineral de...

Sep 4th, 2021 - The addition of selective internal radiation therapy (SIRT) with Y90 resin microspheres to gemcitabine/cisplatin resulted in a median overall survival (OS) of 21.6 months (95% CI, 7.3-25.2) for patients with inoperable intrahepatic cholangiocarcin...